Overview

The Northwest Clinical Research Center (NWCRC) is one of the largest independent research site dedicated to providing the highest quality medical research and care to our patients. We take exceptional pride in the care of our patients as well as integrity in the data provided to our sponsors. Research sponsored by NWCRC has been published in the best of medical journals and presented at national and international scientific meetings.

Each patient receives psychological assessments and health evaluations by our medical staff. Our specialty is psychiatry and the treatment of mood disorders, however we do conduct a variety of medical studies. Arif Khan, M.D., Medical Director and Principal Investigator at the Center, is a Board Certified Psychiatrist and an Adjunct Professor of Psychiatry at Duke University School of Medicine. Dr. Khan has published more than 150 scientific papers. He serves as a reviewer for such journals as The Archives of General Psychiatry, The American Journal of Psychiatry, and Biological Psychiatry. He was extensively involved in research leading to the development of medications such as Prozac, Zoloft, Paxil, Wellbutrin, Effexor, Serzone, Remeron, Celexa, Buspar, Zyprexa, Risperdal, Seroquel, Lexapro, Cymbalta, and Abilify.

Experience

Major Depressive Disorder, Treatment Resistant Depression, Schizophrenia, Bipolar, General Anxiety Disorder, Pediatric constipation, Pediatric Depression, Pediatric ADHD, Insomnia, Diabetes, Low Back Pain, Osteoarthritis, PTSD, Panic Disorders, Social Anxiety, Mania, Autism, ADHD, OCD, Pediatric Bipolar and Schizophrenia, Tourette's, Migraine, Pediatric Migraine, Alzheimer's, Bronchitis, Pneumonia, Neuropathic Pain, Fibromyalgia, Arthritis, Gout, Complex Regional Pain Syndrome (RSD), Chronic Pain, Diabetic Neuralgia, Postherpetic Neuralgia, Cholesterol, Erectile Dysfunction, Constipation, Irritable Bowel Syndrome, Sleep Apnea, Hypertension, Hyperlipidemia, Low Testosterone, COPD, Binge Eating Disorder, Parkinson’s Disease, Cluster Headaches, Uterine Fibroids.

We are proud to have provided medical, psychiatric, and psychological services to the community through our partnership with the pharmaceutical industry since 1995. Our participation has helped to bring over 30 medications to the public.

We have worked with the following CROs: INC Research, Inventive, PPD, ICON, Chiltern, Cognitive, Covance, DSP Research, Jubilant, MedPace, Parexel, Pharmanet, PRA, Premier Research, Quintiles, Stiris Research, World Wide Clinical Trials, Synteract, Syneos, IQVIA.

Some of the sponsors we have worked with include: Abbvie, Abbott, Acasti, Accera, AGI Therapeutics, Akili, Akros, Alder Pharmaceuticals, Alexza, Alkermes, Ampio, Arena, AssureRx, Astrazeneca, Aventis, Avanir Pharmaceuticals, Axsome, Berlex, Biocryst, Biohaven, Boehringer-Ingelheim, Bristol Meyer Squibb, Cenerx, Cephalon, Cerecor, Collegium, Corcept, Cubist, Cyberonics, Daiichi Sankyo, Dr. Reddy’s, Duke Institute, EIP, Eisai, Eli Lilly, EPIX, Fabre-Krame, Forest, Actavis, Allergen, Forum, Envivo, Genaissance, GlaxoSmith, Grunenthal, Impax, Janssen, Roche, Jazz, Johnson and Johnson, Lundbeck, Merck, Methylation Sciences, Neuromed, Neurosearch, Novartis, Organon, Otsuka, Parke-Davis, Pearl, Pfizer, PGX Health, Progenix, Purdue, Renew Research, Repligen, Rexahn, Rhodes, Roche, Sage, Sanofi, Sepracor, Shire, SmithKline, Solvay, Somerset, Spinifex, Sucampo, Sunovian, Supernus, Tal Medical, Teva Pharmaceuticals, Tonix, Vanguard, VistaGen, Vela, Wyeth, Zalicus, and Zogenix.

Facility

We offer inpatient and outpatient services for Phase I-IV studies. We have multiple infusion pumps and chairs, Telemetry machines, ECG machines, refrigerated and ambient centrifuge, -20 and -70 Celsius freezers, dry ice onsite, AED defibrillator, CPR and ACLS certified staff, CLIA waiver, three IATA certified Laboratory Coordinators, complimentary transportation, and separate dedicated staff members for patient visits, recruitment, pharmacy, laboratory, regulatory, and data entry. We average a 1-2 week Contract turnaround timeframe and a 1-2 business day turnaround for Regulatory packages/documents. Our site utilize Central IRBs and have no additional Ethics Committees. We are two miles away from a major hospital and have easy accessibility to public transportation.

Investigator

Arifulla Khan, MD - Over 30 years of Psychiatry (Board Certified) practice and over 25 years in clinical research. Principal Investigator for over 550 studies and Sub-Investigator on over 25 studies.Dr. Khan has been conducting clinical trials in the greater Seattle area since 1984 and founded NWCRC in 1995. In addition, he has published more than 150 scientific papers in leading medical journals. His work on clinical trial design, safety and efficacy is widely recognized and presented at national and international scientific meetings.

Gaylon Kipp, MD - Over 30 years of General Medicine (Board Certified) practice and 12 years of clinical research. Principal Investigator on around 25 studies and Sub-Investigator on over 150 studies.Dr. Kipp is a Board Certified primary care physician and has provided care to patients for over 30 years.  When asked about his work, he says, "I enjoy patient contact and knowing that I’m making a difference through research."

Nalini Reddy, MD - Over 10 years of General Medicine practice and 6 years of clinical research. Sub-Investigator on over 100 studies.

Maria Agrella Diaz, MD - Anesthesiologist/General Practitioner Sub-Investigator on over 50 studies.

Shirin Schilling, MD – Board Certified Psychiatrist Principal Investigator and Sub-Investigator.

Staff

Heather Modeen, Laboratory Technician with over 9 years of experience in clinical research.

Leslie Gills, Lead Regulatory and Data Entry Coordinator with over 9 years of experience in clinical research.

Smitha Sudhakar, Lead Screen Team Coordinator with over 11 years of experience in clinical research.

Lisa Matriccino, Lead Recruitment Coordinator with over 4 years of experience in clinical research.

Gunasheela Jagadeesh, Lead Study Coordinator with over 4 years of experience in clinical research

Patients

Urban and Rural Patient Population
All races and ethnicities in the diverse Pacific Northwest
Children, Adolescents, and Adult studies are available (Ages 4 and up)
No language translations for Informed Consents required

Other

www.facebook.com/NWCRC/

Central IRB