Marjorie Pazzi, RN, BSN, CCRP
Center for Neurosciences
2450 E. River Road
Tucson, AZ 85718
Currently Enrolling Trials
The Center for Neurosciences (CNS) clinical research program is dedicated to delivering excellence in neuroscience research. Board-certified neurologists, pediatric neurologists and neurosurgeons are expert in their respective specialties and have extensive clinical and research experience in a broad range of neurologic diseases affecting adults and children. Therapeutic areas include:
- Epilepsy (both adult and pediatric);
- Parkinson’s disease;
- Alzheimer’s disease;
- Malignant brain tumors;
- Multiple sclerosis;
- Hearing loss; and
- Autism spectrum disorders.
Our program is primarily involved with sponsored phase 2 to 4 clinical trials, but several of our investigators have developed and conducted investigator-initiated studies and compassionate-use trials. Our clinic is always growing and currently has a database of more than 67,000 active patients.
All CNS principal investigators and sub-investigators are certified in good clinical practice and human subjects protection.
Adult Neurology and Neurosurgery
- Michael Badruddoja, MD, is a board-certified neurologist with fellowship training in neuro-oncology; his special interest is in the treatment of malignant gliomas and Alzheimer’s disease. He is a principal investigator on phase 2 to 3 Alzheimer’s disease and phase 1 to 2 glioblastoma trials, including several cancer immunotherapy studies.
- Abhay Sanan, MD, is board-certified by the American Board of Neurological Surgery. He completed his fellowship in skull base/cerebrovascular surgery. He is the chief of neurosurgery at Northwest Medical Center and St. Mary’s Hospital. Dr. Sanan is also a principal investigator for several neurosurgical device studies.
Francisco Valdivia, MD, is a board-certified neurologist, a member of the Consortium of Multiple Sclerosis Centers and a multiple sclerosis-certified specialist. He is a principal investigator on several multiple sclerosis trials. He is also the medical director of stroke at St. Mary’s Hospital. Dr. Valdivia speaks fluent Spanish.
- Abraham Jacob, MD, specializes in otology, neurotology and cranial base surgery. He is the medical director of ear and hearing at The Center for Neurosciences and the medical director for neurotology services at Tucson Medical Center. He is principal investigator for several ear and hearing studies.
- Dinesh Talwar, MD, is a board-certified child neurologist and clinical neurophysiologist. He has fellowship training in EEG and neurophysiology. Dr. Talwar’s special interests include childhood epilepsy and migraines, and he is principal investigator on multiple pediatric epilepsy and migraine trials.
- Marjorie Pazzi, RN, BSN, clinical research director, has coordinated clinical trials since 2003 and has more than 20 years’ experience in neurology nursing. Ms. Pazzi manages clinical research operations and is the primary point of contact for sponsors and contract research organizations. She is a certified clinical research professional. She speaks proficient Spanish.
- Ashley Nix (Burleigh), lead CRC, earned her associate of applied science degree in clinical research at Pima Community College. She has many years of experience in coordinating neuroscience clinical trials. She supervises the clinical research team.
- The CNS clinical research program partners with highly skilled professionals in the community who specialize in neuro-radiology, nuclear medicine, dermatology, cardiology and ophthalmology when consultations or services are required for research protocols. Our contracted, board-certified psychologists perform a variety of psychometric assessments in adults and children.
CNS not only serves the metropolitan Tucson area but also, due to several outreach clinics in small communities throughout the state, reaches about 1.5 million people in southern Arizona. This region has a culturally and ethnically diverse patient population, with 60 percent Caucasian, 33 percent Hispanic, 2 percent African American, 3 percent Native American and 2 percent Asian. Several of our investigators are fluent Spanish speakers.
CNS has collaborated with numerous pharmaceutical companies and contract research organizations on all phases of research. We offer expeditious study startup with prompt contract execution and regulatory approval. We utilize centralized IRBs such as Copernicus, Quorum, Schulman, Western and New England IRBs. With access to an extensive patient base from which to draw as well as a comprehensive research database, we are frequently an early-enrolling site and typically meet or exceed enrollment goals.