• SKIP TO CONTENT
  • SKIP NAVIGATION
  • Patient Resources
    • COVID-19 Patient Resource Center
    • Clinical Trials
    • Search Clinical Trials
    • Patient Notification System
    • What is Clinical Research?
    • Volunteering for a Clinical Trial
    • Understanding Informed Consent
    • Useful Resources
    • FDA Approved Drugs
  • Professional Resources
    • Research Center Profiles
    • Clinical Trial Listings
    • Market Research
    • FDA Approved Drugs
    • Training Guides
    • Books
    • Events
    • Newsletters
    • JobWatch
    • White Papers
    • Patient Education
    • SOPs
    • eCFR and Guidances
  • White Papers
  • Trial Listings
  • Advertise
  • COVID-19
  • iConnect
  • Sign In
  • Create Account
  • Sign Out
  • My Account
Home » Directories » FDA Approved Drugs » Humalog (insulin lispro)

AND
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

Humalog (insulin lispro)

  • Profile

Profile

Contact Information

Currently Enrolling Trials

    Show More

    General Information

    Humalog, an insulin analog of recombinant DNA origin, has been approved for the treatment of type I and type II diabetes. Humalog is the first of a new type of insulin that is designed to mimic the body's own normal rapid insulin response.

    A?

    Clinical Results

    The approval of Humalog was based on data from worldwide clinical studies that included approximately 3,000 subjects who were evaluated over three years. Diabetics who participated in clinical trials injected Humalog within 15 minutes of eating a meal instead of injecting regular human insulin between 20 and 45 minutes before. Clinical trial evidence showed that Humalog acted faster than regular human insulin to control blood-glucose levels after a meal.

    Mechanism of Action

    Humalog was discovered and developed by scientists who found that the absorption of insulin injected under the skin could be accelerated by changing the order of two amino acids in the human insulin molecule. Humalog is designed to more closely mimic the body's own natural output in response to eating a meal.

    Additional Information

    More than 16 million people in the United States suffer from diabetes, which is the fourth-leading cause of death each year. In the United States alone, the disease costs society some $92 billion each year, according to the American Diabetes Association.

    People with diabetes have to monitor blood-glucose levels and sometimes inject insulin several times a day to help their bodies process food. For people who are using regular human insulin, health care professionals recommend that injections be timed at least 30 to 45 minutes prior to a meal to allow the medication to begin working.

    A 1995 survey of 453 insulin-using subjects with type 1 and type 2 diabetes showed that 43% injected insulin closer to their meals than recommended. Only 25% of the subjects surveyed took their insulin more than 30 minutes before they ate. Taking insulin too close to a meal can increase a subject's risk of hyperglycemia (high blood sugar) shortly after the meal and hypoglycemia (low blood sugar) before the next meal.

    Approval Date: 1996-06-01
    Company Name: Eli Lilly
    Back to Listings

    Upcoming Events

    • 26Jan

      Reducing Complexity in Starting Clinical Trials – More Patients, Faster Startup

    • 27Jan

      Medical Device Clinical Trials in China: Latest Regulatory Developments

    • 11Feb

      Lab X.0: Addressing Quality and Compliance Challenges in Laboratory Operations in the COVID-19 All-Digital Era

    • 23Mar

      Data Integrity for GCP Professionals: Core Requirements, Expectations and Challenges

    • 26Apr

      MAGI's Clinical Research vConference — Spring 2021

    Featured Products

    • Regenerative Medicine – Steps to Accelerate Development : PDF

      Regenerative Medicine: Steps to Accelerate Development

    • Clinical Trial Agreements — A Guide to Key Words and Phrases : PDF

      Clinical Trial Agreements: A Guide to Key Words and Phrases

    Featured Stories

    • Virtual Doctoer

      Simple Changes Can Make Trials More Patient Friendly

    • Drug approval

      Two-Thirds of Trial Subjects for Drug Approvals Are Outside the U.S.

    • VaccinewithNeedle-360x240.png

      Rules of Vaccine Approval May Be Changing, But Statistical Analysis Tools Remain Constant

    • AskTheExperts-360x240.png

      Ask the Experts: Trial Operations Adjustments in a Remote World

    Standard Operating Procedures for Risk-Based Monitoring of Clinical Trials

    The information you need to adapt your monitoring plan to changing times.

    Learn More Here
    • About Us
    • Contact Us
    • Privacy Policy
    • Do Not Sell My Personal Information

    Footer Logo

    300 N. Washington St., Suite 200, Falls Church, VA 22046, USA

    Phone 617.948.5100 – Toll free 866.219.3440

    Copyright © 2021. All Rights Reserved. Design, CMS, Hosting & Web Development :: ePublishing