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Home » Directories » FDA Approved Drugs » Femara (letrozole)

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Femara (letrozole)

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    General Information

    Femara (letrozole), a late-term hormonal therapy, has been approved as a treatment for breast cancer. Femara comes in 2.5 mg doses, recommended once daily.

    Clinical Results

    In a randomized study, 18.4% of patients reported a complete or partial tumor response.

    Side Effects

    Common side effects reported include musculoskeletal pain (21%), nausea (13%), headache (9%), joint pain (8%), or fatigue (8%).

    Mechanism of Action

    A second-line anti-estrogen therapy, the drug prevents the transformation of androgen compounds into estrogen by blocking the effects of the aromatase enzyme.

    Approval Date: 1997-07-01
    Company Name: Novartis
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