• SKIP TO CONTENT
  • SKIP NAVIGATION
  • Patient Resources
    • COVID-19 Patient Resource Center
    • Clinical Trials
    • Search Clinical Trials
    • Patient Notification System
    • What is Clinical Research?
    • Volunteering for a Clinical Trial
    • Understanding Informed Consent
    • Useful Resources
    • FDA Approved Drugs
  • Professional Resources
    • Research Center Profiles
    • Clinical Trial Listings
    • Market Research
    • FDA Approved Drugs
    • Training Guides
    • Books
    • eLearning
    • Events
    • Newsletters
    • JobWatch
    • White Papers
    • SOPs
    • eCFR and Guidances
  • White Papers
  • Trial Listings
  • Advertise
  • COVID-19
  • iConnect
  • Sign In
  • Create Account
  • Sign Out
  • My Account
Home » Directories » FDA Approved Drugs » Cinqair (reslizumab)

AND
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

Cinqair (reslizumab)

  • Profile

Profile

Contact Information

Contact: Teva Pharmaceuticals
Website: www.cinqair.com

Currently Enrolling Trials

    Show More

    General Information

    Cinqair (reslizumab) is an interleukin-5 antagonist monoclonal antibody (IgG4 kappa).

    Cinqair is specifically indicated for the add-on maintenance treatment of patients with severe asthma aged 18 years and older with an eosinophilic phenotype.

    Cinqair is supplied as a solution for intravenous administration. The recommended dose is 3 mg/kg once every 4 weeks administered by intravenous infusion over 20-50 minutes.

    Mechanism of Action

    Cinqair (reslizumab) is an interleukin-5 antagonist monoclonal antibody (IgG4 kappa). IL-5 is the major cytokine responsible for the growth and differentiation, recruitment, activation, and survival of eosinophils. By inhibiting IL-5 signaling, reslizumab reduces the production and survival of eosinophils; however, the mechanism of reslizumab action in asthma has not been definitively established. 

    Side Effects

    Adverse effects associated with the use of Cinqair may include, but is not limited to, the following:

    • oropharyngeal pain

    Cinqair comes with a black box warning of the potential for anaphylaxis.

    Clinical Trial Results

    The FDA approval of Cinqair was based on four double-blind, randomized, placebo‑controlled trials in 1,028 adult and adolescent patients with severe asthma on currently available therapies. Cinqair 3 mg/kg or a placebo was administered to patients every four weeks as an add-on asthma treatment. Compared with placebo, patients receiving Cinqair had reductions in asthma exacerbations of up to 59% as well as significant improvement in lung function, symptoms, and asthma-related quality of life. 

    Approval Date: 2016-03-01
    Company Name: Teva Pharmaceuticals
    Back to Listings

    Upcoming Events

    • 24May

      Powering an Effective Oversight Strategy with Clinical and Operational Insights

    • 25May

      2022 WCG Avoca Quality & Innovation Summit: Own the Future

    • 28Jun

      Effective Root Cause Analysis and CAPA Investigations for the Life Sciences

    • 16Oct

      WCG MAGI's Clinical Research Hybrid Conference - 2022 West

    Featured Products

    • Spreadsheet Validation: Tools and Techniques to Make Data in Excel Compliant

      Spreadsheet Validation: Tools and Techniques to Make Data in Excel Compliant

    • Surviving an FDA GCP Inspection

      Surviving an FDA GCP Inspection: Resources for Investigators, Sponsors, CROs and IRBs

    Featured Stories

    • Protocol-360x240.png

      Avoid Deviations by Making Protocol Review a Team Effort

    • SelectionProcess-360x240.png

      Give Us a Voice: Sites Clamor for a Say on Vendor Selection

    • Convince-360x240.png

      Use Data and Details to Convince Site Leadership to Add Staff

    • AsktheExpertsBadge-360x240.png

      Ask the Experts: Listing Trial Staff and Others on the Statement of Investigator

    Standard Operating Procedures for Risk-Based Monitoring of Clinical Trials

    The information you need to adapt your monitoring plan to changing times.

    Learn More Here
    • About Us
    • Contact Us
    • Privacy Policy
    • Do Not Sell My Personal Information

    Footer Logo

    300 N. Washington St., Suite 200, Falls Church, VA 22046, USA

    Phone 617.948.5100 – Toll free 866.219.3440

    Copyright © 2022. All Rights Reserved. Design, CMS, Hosting & Web Development :: ePublishing