Biaxin XL Tablets is an extended-release form of the antibiotic Biaxin (clarithromycin). Biaxin XL is indicated for the treatment of:
[Biaxin Tablets (non extended-release) are also indicated for pharyngitis/tonsillitis, pneumonia, and uncomplicated skin and skin structure.]
Biaxin XL should be taken with food even though Biaxin Tablets and oral suspension may be taken with or without food.
94% of patients with Acute Exacerbation of Chronic Bronchitis (AECB) and 97% of patients with Acute Maxillary Sinusitis (AMS) taking Biaxin Tablets in clinical studies were cured or showed significant improvement.
The most common side effects are:
Discontinuation of treatment due to these adverse events occurred in fewer patients taking Biaxin XL than patients taking Biaxin Tablets.
Post-marketing spontaneously-reported adverse events included:
Biaxin XL is contraindicated in patients with allergies to
clarithromycin, erythromycin, or any macrolide antibiotic.
Concomitant administration of Biaxin with cisapride, pimozide, or terfenadine is contraindicated. Fatalities due to interactions between clarithromycin and these drugs have been reported.
Clarithromycin should not be administered to pregnant women.