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Headaches Clinical Trials

A listing of Headaches medical research trials actively recruiting patient volunteers. Search for the closest city to find more detailed information on a research study in your area.

RESULTS

Found (41) clinical trials

A Study to Test if Fremanezumab Reduces Headache in Patients With Posttraumatic Headache (PTH)

This is a 12-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group study to evaluate the safety and efficacy of fremanezumab in adult patients aged 18 to 70 years, inclusive, for the prevention of PTH. Patients will provide written informed consent and during study visits they will use an electronic diary application daily, ...

Phase

161.23 miles

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Stereotactic Body Radiation Therapy and Vertebroplasty in Treating Patients With Localized Spinal Metastasis

OBJECTIVES Primary To determine the efficacy of stereotactic body radiotherapy in reducing pain at 3 months in patients with localized spinal metastasis. Secondary To determine the duration of pain response at the treated site(s) scored as the time of maximal pain relief to an increase of 2 points on the ...

Phase

223.77 miles

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Protocol #: 20150308 Migraine prevention in Subjects with Chronic Migraine (CM) or Episodic Migraine (EM) comparing the treatment medication AMG 301 to placebo.

Phase

226.7 miles

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This time sensitive flu like illness research study is looking for subjects with a current fever of at least 100.4 at time of screening along with flu like symptoms such as headache, tiredness, feverishness, cough, sore throat, nasal congestion. Study has 4 visits and last 14 days. Time sensitive visits ...

Phase

675.5 miles

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This is a Prospective, Randomized, Vehicle‐controlled, Double‐blind, Multi-center, 3-arm study assessing the safety, tolerability, and efficacy of B244 delivered as an intranasal spray for preventive treatment in subjects with episodic migraine.

Phase

708.3 miles

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Spinal and Supra-Spinal Pain Mechanisms in Patients With Fibromyalgia

Fibromyalgia (FM) patients have increased windup (WU). However, WU of FM patients is only quantitatively but not qualitatively different from healthy controls (HC). Thus WU abnormalities of FM patients could be the result of supra-spinal and not the result of spinal pain mechanisms. The study team will test this hypothesis ...

Phase

781.46 miles

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A Study to Examine the Efficacy and Safety of REGN5069 in Patients With Pain Due to Osteoarthritis of the Knee

The primary objective of the study is to evaluate the efficacy of REGN5069 compared to placebo in patients with pain due to radiographically-confirmed OA of the knee who have a history of inadequate joint pain relief or intolerance to current analgesic therapy. The secondary objectives of the study are: To ...

Phase

845.89 miles

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A Pilot Study of TRV130 for the Treatment of Fracture Pain

This study is designed to evaluate the analgesic efficacy of TRV130 for the treatment of moderate to severe acute pain associated with a long bone fracture in patients presenting to the ED. The safety and tolerability of TRV130 will also be evaluated in this open-label pilot study.

Phase

865.82 miles

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Distinct Mechanisms of Cognitive Behavioral Therapy Effects in Youth With Migraine

Pediatric migraine is a prevalent disorder that results in significant pain and disability for children and adolescents. Little is known about the distinct brain changes that occur in youth with migraine when they receive cognitive behavioral therapy, which is known to decrease headache days for these patients. Pediatric medical and ...

Phase

895.89 miles

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D-cycloserine for the Treatment of Chronic Refractory Low Back Pain

This is a 26-week, double-blind, randomized, placebo-controlled two-arm parallel-group trial of d-cycloserine, a pharmacological treatment selected based on positive results from previous preclinical and clinical studies, for the treatment of chronic, refractory low back pain (CBP). After a 2-week screening period, individuals will be randomized to receive either 12 weeks ...

Phase

943.21 miles

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