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Headaches Clinical Trials

A listing of Headaches medical research trials actively recruiting patient volunteers. Search for the closest city to find more detailed information on a research study in your area.

RESULTS

Found (65) clinical trials

Evaluate The Pharmacokinetics and Safety Of Oxycodone Oral Solution In Pediatric and Adolescent Subjects

This is a Phase IV study to characterize the pharmacokinetics and to evaluate the safety of Oxycodone Oral Solution administered to pediatric and adolescent subjects for postoperative pain. It is an open label, multicenter study conducted at up to 10 sites. Subjects will be enrolled preoperatively up to 14 days ...

Phase

4.32 miles

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Embrace TDD: Post-Market Study to Evaluate Intrathecal Morphine as an Alternative to Systemic Opioids for Chronic Pain

Subjects will be assessed for pain control and opioid-related side effects following a route of delivery change from systemic opioids to IT morphine therapy.

Phase

45.33 miles

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Epidural and Intravenous Patient-Controlled Analgesia Following Lumbar Spinal Fusion Surgery

Study Design: Prospective study of 58 subjects undergoing elective Lumbar Spinal Fusion (1-3 levels- posterior approach) at UTSW Zale Lipshy University Hospital with: Continuous Lumbar Epidural Analgesia (Patient-Controlled Epidural Analgesia- PCEA groups) Intravenous Patient-Controlled Analgesia (IV PCA) Study Interventions - The intervention to be evaluated in this study is epidural ...

Phase

223.77 miles

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A Study to Evaluate the Efficacy and Safety of Erenumab in Adults With Medication Overuse Headache

Study 20170703 is a phase 4, randomized, double-blind, double-dummy, parallel-group, placebo-controlled study to evaluate the safety and efficacy of erenumab against placebo in a chronic migraine (CM) population with medication overuse headache (MOH) and prior history of treatment failure. Subjects will be enrolled based on fulfilment of the International Classification ...

Phase

226.86 miles

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Effect of Erenumab-aooe on Disability and Work Productivity in Employed Subjects With Episodic Migraine

Migraine prevention continues to be an area of large, unmet medical need, with existing therapies often having modest efficacy and poor tolerability. Calcitonin gene-related peptide (CGRP) has an important role in the pathophysiology of migraine. Erenumab-aooe is a fully human monoclonal antibody that targets the CGRP receptor, and interrupts its ...

Phase

249.37 miles

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A Study to Evaluate the Efficacy and Safety of Fremanezumab for Preventive Treatment of Migraine in Patients With Major Depressive Disorder

The primary objective is to evaluate the efficacy of monthly 225 mg sc fremanezumab in adult patients with migraine and major depressive disorder (MDD) The secondary objectives are to evaluate the efficacy of monthly 225 mg sc of fremanezumab in adult patients with migraine and MDD on the reduction of ...

Phase

387.4 miles

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Baclofen as a Perioperative Analgesic Adjuvant

Postoperative pain continues to be a significant clinical problem. Use of perioperative adjuvants has improved postoperative pain control. The GABA-B receptor agonist, baclofen, is an appropriate drug to trial as such an analgesic adjuvant. Therefore, the investigators will conduct a study designed to determine whether or not a single, oral ...

Phase

566.39 miles

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Surgery Prevention by Transforaminal Injection of Epidural Steroids for Cervical Radicular Pain

Cervical radicular pain is a common cause of disability and pain in the upper extremity and neck with an annual incidence of 83.2/100,000 (1). The initial treatment is conservative and includes relative rest, use of anti-inflammatory and analgesic medication, as well as physical therapy and home exercise. For patients who ...

Phase

925.81 miles

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A Comparison of Dexamethasone and Triamcinolone for Ultrasound-guided Occipital C2 Nerve Blocks

Greater occipital nerve (GON) injection is a commonly performed diagnostic and therapeutic procedure in headache patients. GON blocks have been shown to be effective in the treatment of a variety of headaches including occipital neuralgia, migraine, vascular headache, cluster headache, cervicogenic headache, and post-concussive headache.The GON provides sensory innervation to ...

Phase

943.21 miles

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Do Cervical Interlaminar Epidural Steroid Injections With Low-dose Lidocaine Cause Transient Objective Upper Extremity Weakness? A Prospective Randomized Controlled Trial

Control Group: Prospective observational cohort study of UE strength in pain clinic patients undergoing trigger point injections and occipital nerve injections to serve as controls to measure variability of strength testing before and 30 min after such an intervention. Experimental Groups: Prospective, randomized, controlled, double blinded trial in patients undergoing ...

Phase

943.21 miles

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