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Dementia Clinical Trials

A listing of Dementia medical research trials actively recruiting patient volunteers. Search for the closest city to find more detailed information on a research study in your area.

RESULTS

Found (913) clinical trials

Family Telemental Health Intervention for Veterans With Dementia

Background The increase in prevalence of dementia over the last 50 years has resulted in a concomitant rise in the number of families facing the physical, emotional, and psychological stress associated with caregiving. Behavioral symptoms that occur in persons with dementia (PWD) lead to negative mental and physical health outcomes ...

Phase N/A

2.14 miles

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Improving Accessibility and Personalization of CR for Schizophrenia

Cognitive remediation (CR) is an evidence-based practice to treat the pervasive and significant cognitive deficits that contribute to functional decline in schizophrenia. The New York State Office of Mental Health (OMH) has teamed with the Principal Investigator to be the first, and largest state system of care to implement a ...

Phase N/A

2.55 miles

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A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

This study will assess the effects of each of the two therapies given separately, both targeting amyloid, on cognition, global clinical status, and underlying pathology in participants at risk for the onset of clinical symptoms of Alzheimer's disease (AD). Cognitively unimpaired individuals with two APOE4 genes and age 60 to ...

Phase

2.62 miles

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A Proof of Concept Study of the Prevention of Mild Cognitive Impairment and Eventual Alzheimer's Disease Using F18 Flutemetamol

This is an investigator-initiated study comparing two types of FDA-approved anti-depressants, Escitalopram and Venlafaxine, to placebo, in order to determine if these medications have positive effects on cognition and memory in those who are between the ages of 50 to 89 years old, who are cognitively normal, and who have ...

Phase

2.62 miles

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A Study of LY3154207 in Participants With Parkinson's Disease Dementia

A randomized placebo-controlled trial in individuals with Parkinson's disease dementia to evaluate the safety and efficacy of three doses of study drug LY3154207 in participants with mild-to-moderate Parkinson's disease dementia treated for 12 weeks.

Phase

2.62 miles

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Predictors of Cognitive Decline in Normal Aging

Studies of normal aging and mild cognitive impairment (MCI) show that loss of neurons and reduction in size of the hippocampal part of the brain predict a person's conversion from MCI to Alzheimer's disease (AD). Increases in tangle-related abnormal tau proteins, specifically P-tau231, also appear to be related. This study ...

Phase N/A

2.62 miles

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Biomarkers and Early Alzheimer's Disease

The goal of this project is to use magnetic resonance imaging (MRI) and cerebrospinal fluid (CSF) biomarkers to identify cognitively normal participants who show the earliest clinically detectable brain changes of Alzheimer's disease (AD). The major hypothesis for this study is that CSF P-tau231 measurement improves the accuracy of MRI ...

Phase N/A

2.62 miles

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An Innovative Psychosocial Intervention for Adult-Child Caregivers of Parents With Alzheimer's Disease

Caring for an elderly parent is a growing societal problem, and many studies have shown that caring for a person with dementia can have a negative impact on a caregiver's psychological and physical health, social life and career, and relationship with the patient. Stress and coping models proposed in the ...

Phase N/A

2.62 miles

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Couples Coping With Alzheimer's Disease

The majority of people with Alzheimer's disease (AD) live at home with their spouses. AD erodes the ability of each member of the couple to support each other. Moreover, couples may be unaccustomed to seeking or accepting emotional and practical support from family members or formal resources. Even though AD ...

Phase N/A

2.62 miles

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Anti-viral Therapy in Alzheimer's Disease

Many viruses are latent for decades before being reactivated in the brain by stress, immune compromise, or other factors. After the initial oral infection, herpes simplex virus-1 (HSV1) becomes latent in the trigeminal ganglion and can later enter the brain via retrograde axonal transport, often targeting the temporal lobes. HSV1 ...

Phase

2.62 miles

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