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Covid Clinical Trials

A listing of Covid medical research trials actively recruiting patient volunteers. Search for the closest city to find more detailed information on a research study in your area.

RESULTS

Found (858) clinical trials

The Kentucky Neuroscience Institute is conducting a study to learn how the 2020 Coronavirus pandemic (COVID-19) has affected people. We are studying the psychological, social, physical, and emotional effects of social/physical distancing during this time, and what activities people are engaging in. People who complete the 30-minute survey can enter …

Phase N/A

The study is designed to compare two COVID-19 treatment regimens in hospitalized adult subjects who are diagnosed with severe COVID 19.  The investigational medication is called CD24Fc. Participants will be randomly assigned to one of two treatment "arms" for the study and neither the participant, nor the study team will …

Phase

Prone Positioning and Regional Ventilation in Mechanically Ventilated COVID-19 Patients

Patients with acute respiratory distress syndrome (ARDS) frequently develop atelectasis in dorsal lung regions because of gravity and the compression by the heart and the diaphragm. Since lung perfusion is predominantly distributed in lower lung regions, a reduction of ventilation in these areas results in further ventilation-perfusion mismatch, called shunt. …

Phase N/A

A Study to Assess the Feasibility of Screening for SARS-CoV-2 Among Healthy Workers

This study has been designed to assess the feasibility of screening asymptomatic workers and to investigate the extent of infection, as determined by pharyngeal swaps analysis and immune response against the virus and virus specific CD4+ and CD8+ T-cell analysis. Furthermore, the extent to which virus-specific CD4+ and CD8+ T-cells …

Phase N/A

Low Dose Anti-inflammatory Radiotherapy for the Treatment of Pneumonia by COVID-19

Study design: This is a prospective multicenter study in 2 phases: Exploratory phase. It will include 10 patients, to assess the feasibility and efficacy of low-dose lung irradiation. If a minimum efficiency of 30% is not achieved, the study will not be continued. Comparative phase in two groups, a control …

Phase N/A

A Study to Assess the Efficacy and Safety of Gimsilumab in Subjects With Lung Injury or Acute Respiratory Distress Syndrome Secondary to COVID-19 (BREATHE).

Gimsilumab is a monoclonal antibody against granulocyte macrophage-colony stimulating factor (GM-CSF), which is a myeloid cell growth factor and pro- inflammatory cytokine. Late stages of COVID-19 can be marked by a "cytokine storm" and the overactivation of inflammatory myeloid cells that infiltrate and damage tissue, such as the lungs. Inhibition …

Phase

Efficacy and Safety of Novel Treatment Options for Adults With COVID-19 Pneumonia

The study is a randomized, double blinded, placebo-controlled, multicenter, multi-stage study with six parallel treatment arms consisting of either convalescent plasma, sarilumab, hydroxychloroquine, baricitinib, intravenous and subcutaneous placebo, or oral placebo. We plan to enroll 250 patients in each arm, with a total of 1500 patients yielding a statistical power …

Phase

Investigation of the B- and T-cell Repertoire and Immune Response in Patients With Acute and Resolved COVID-19 Infection

Background Patients infected with COVID-19 have an unpredictable risk to worsen and die, making it difficult to decide who can quarantine at home and who should be monitored for respiratory failure as an inpatient. This risk may be related in part to the patient s immune response which can be …

Phase N/A

Endovascular Thrombectomy in COVID-19 Infected Patients

Since the identification of the first case of Severe Acute Respiratory Syndrome (SARS) CoV-2 infection in December 2019 in Wuhan, China, the global number of confirmed COVID-19 cases is roughly 5 000 000, with 216 involved countries. Increasing evidence shows that SARS-CoV-2 may be associated with neurological manifestations, with up …

Phase N/A

Microvascular Flow and Reactivity in Patients Presenting in the Acute Phase of COVID-19.

An association between the presence of previous cardiovascular disease and adverse prognosis has been demonstrated in patients with COVID-19 (coronavirus disease-19), presenting increases of up to 5-10 times in mortality. As an initial process, the SARS-CoV-2 virus, anchored in the transmembrane angiotensin-converting enzyme 2 (ECA2), penetrates host cells, including endothelial …

Phase N/A