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Found 21 clinical trials
MRI - Guided Adaptive RadioTHerapy for Reducing XerostomiA in Head and Neck Cancer (MARTHA-trial)

accelerator and an integrated low-field MRI, could allow a) better visualization of tumor and organs at risk, such as parotid glands during patient positioning and daily treatment, b) daily imaging without

squamous cell carcinoma of the oral cavity
intensity-modulated radiation therapy
mouth cancer
locally advanced squamous cell carcinoma
  • 23 Jan, 2021
  • 1 location
A Study of ALM-488 to Highlight Nerves in Patients Undergoing Head & Neck Surgery

Phase 1/2 study of ALM-488 to highlight nerves in patients undergoing head & neck surgery.

serum pregnancy test
neck dissection
hormonal birth control
  • 04 Feb, 2021
  • 2 locations
Prospective Pilot Study Evaluating Dental Side Effects of Radiotherapy on Subjects Treated for Head and Neck Cancer

the pre-treatment imaging. In the same way the mean dose and the V25 (the volume receiving 25 Gy) of the homo- and the heterolateral parotid gland will be calculated. Based on our predictive model

  • 27 Jan, 2021
  • 3 locations
Octreotide VS Placebo in Prevention of Salivary Fistulae After Post Radiation Salvage Surgery

Salivary fistulae have been the bane of surgical salvage in the era of primary chemoradiation for head and neck (H&N) cancers. The "blame"of prior chemoradiation tissue damage encouraged compensatory surgical techniques that focused on the insertion of non-irradiated tissue into the field. This study emphasizes a paradigm shift in the …

  • 23 Jan, 2021
  • 1 location
Multiparametric Magnetic Resonance Imaging Versus Fine Needle Aspiration Cytology for Parotid Gland Neoplasms

Parotid gland tumors are mostly treated surgically, but the extent of parotidectomy is decided upon preoperative work-up information. Preoperative management generally includes clinical

  • 22 Jan, 2021
  • 1 location
FArial NErf MRI in the Preoperative Assessment of PArotide Tumors

st visit: Inclusion, 3Tesla injected parotid MRI performed as part of routine care for characterization, to which two specific high resolution sequences will be added. Evaluation of the

  • 05 Feb, 2021
  • 1 location
Characterization of Diseases With Salivary Gland Involvement

the opening of the parotid gland duct on the inside of the cheek. A saline solution (in a syringe) will fill the duct. Swishing a saltwater solution in the mouth for 10 seconds and then

cancer treatment
dry eyes
  • 14 Apr, 2021
  • 1 location
A Multi-center Retrospective Analysis of Clinical Character Outcome and Prognosis of Lymphoepithelioma-like Carcinoma

The investigators retrospective collect the clinical data of patients diagnosed with lymphoepithelioma-like carcinoma, including primary site, gender, age, smoking history, tumor stage, time of initial treatment, EBV-DNA copy number, first-line treatment and survival status.

  • 26 Jan, 2021
  • 1 location
Post-radiation Dental Disease Amongst Head and Neck Cancer Patients

radiation dose, 'spared' parotid gland radiation dose, tumour location, and post-radiotherapy dental disease. Methods A prospective cohort study will be undertaken in HANC patients treated with

  • 22 Jan, 2021
  • 1 location
Use of Multiparametric MRI in the Management of Head and Neck Cancer: a Prospective Analysis

The investigators aim to validate specific MRI parameters that could improve diagnostic accuracy of metastatic cervical lymph nodes in patients with a squamous cell carcinoma in the head and neck region. Moreover, we aim to explore specific MRI parameters that could improve diagnostic accuracy of bone invasion and tumour relapse, …

squamous cell carcinoma
ct scan
advanced head and neck carcinoma
positron emission tomography
  • 02 Feb, 2021
  • 1 location