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Found 9 clinical trials
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Response to the SHINGRIX Varicella Zoster Virus (VZV) Vaccine in Chronic Lymphocytic Leukemia (CLL) Patients that are Treatment Naive or Receiving Bruton s-Tyrosine Kinase Inhibitor (BTK-I) Therapy

. Scientists had thought people with chronic lymphocytic leukemia (CLL) should not get the shingles vaccine. Now there is a new shingles vaccine that is not live and cannot cause shingles. The new shingles

ibrutinib
cancer
lymphoma
acalabrutinib
chronic lymphocytic leukemia
  • 216 views
  • 09 Apr, 2019
  • 1 location
None
Systems Biology of Zoster Vaccine

The purpose of the study is to better understand how the immune system responds to the new herpes zoster (shingles) vaccine (Shingrix). The study will be looking at certain markers in the blood

herpes
vaccination
zoster vaccine
shingrix
  • 86 views
  • 26 Dec, 2021
  • 1 location
None
Age Differences in Influenza and Herpes Zoster Vaccine Responses (INFLUENZA-SHINGRIX)

Vaccines are used to prevent infectious diseases worldwide. Unfortunately, many vaccines, like the flu vaccine, are less effective in older adults. This single-centre open label partially randomised, partially placebo-controlled trial evaluates the differences in immune response between young and older adults after vaccination with a quadrivalent inactivated influenza vaccine and …

quadrivalent inactivated influenza vaccine
fluarix
Accepts healthy volunteers
zoster vaccine
vaccination
  • 0 views
  • 16 Dec, 2021
  • 1 location
None
Recombinant Zoster Vaccine in Stable SLE Patients

reactivation limited the use of live-attenuated shingles vaccine in SLE patients, especially in whom with high dose of prednisone or immunosuppressants. Whether the introduction of recombinant zoster vaccine

treatment regimen
varicella
prednisone
belimumab
mycophenolate
  • 0 views
  • 10 Oct, 2021
None
Persistence of Protection by Shingrix

The study plans to learn more about how the shingles vaccine, Shingrix (SRX), successfully prevents shingles in older people. Two vaccines are currently approved by the Food and Drug

varicella
zoster vaccine
chickenpox
shingrix
hysterectomy
  • 99 views
  • 18 Feb, 2021
  • 1 location
None
Immunogenicity of Herpes Zoster Subunit Vaccine in Inflammatory Bowel Disease Patients Treated With Vedolizumab

Inflammatory bowel disease (IBD) is a chronic inflammatory state of the gastrointestinal tract(1) affecting 1.6-3.1 million people in the United States. Patients with IBD are treated with immunosuppressants that increase their risk of herpes zoster (HZ), also known as shingles. Those with IBD have a two-fold increased risk for HZ …

varicella
herpes
golimumab
certolizumab pegol
subunit vaccine
  • 36 views
  • 19 Jan, 2022
  • 1 location
None
The Immunogenicity and Safety of Zostavax in Rheumatoid Arthritis Patients Using Abatacept

This investigator-initiated study will serve as a sub-study for the American College of Rheumatology-sponsored VERVE protocol currently funded by the NIH. This double-blinded multicenter randomized pragmatic trial is designed to determine whether Zostavax or Shingrix are safe and effective in patients with rheumatoid arthritis (RA) currently using anti-tumor necrosis factor …

varicella
arthritis
abatacept
abatacept therapy
chickenpox
  • 151 views
  • 20 Aug, 2021
  • 4 locations
None
Solid Organ Transplant SHINGRIX

This study will assess the immune responses to the recombinant, AS01-adjuvanted varicella zoster virus subunit (HZ/su) vaccine or SHINGRIX in immunosuppressed patients, particularly those who have received a renal transplant, and to better understand if the vaccine and perhaps other adjuvanted vaccines are safe in these patients. 30 participants will …

varicella
organ transplantation
solid organ transplant
immunosuppression
vaccination
  • 48 views
  • 16 Feb, 2021
  • 4 locations
None
Long-term Immunogenicity of a Live Herpes Zoster Vaccine in Systemic Lupus Erythematosus (SLE) Patients

A recent randomized controlled trial (RCT) from our group has demonstrated safety and immune response (both humoral and cell-mediated) of the live-attenuated herpes zoster (HZ) vaccine (Zostavax) in stable systemic lupus erythematosus (SLE) patients with a previous history of HZ or varicella infection. An important research question is whether the …

  • 0 views
  • 26 Dec, 2021
  • 1 location