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Found 11 clinical trials
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Pilot study to evaluate the next-dose transition from Zolpidem to Lemborexant for treatment of insomnia.

The purpose of this study is to evaluate the next-dose transition from Zolpidem (Ambien) to Lamborexant for treatment of insomnia.  

zolpidem
  • 193 views
  • 23 Nov, 2020
  • 1 location
Randomized Controlled Trial of Extended-Release Buprenorphine vs. Sublingual Buprenorphine for the Treatment of Opioid Use Disorder Patients Using Fentanyl

The study is 12-week, randomized, open-label study comparing injectable extended-release buprenorphine (Sublocade) to standard therapy (sublingual buprenorphine), to see if Sublocade will be more helpful in treating opiate use for individuals testing positive for fentanyl and related high potency drugs (HPSO). Those receiving Sublocade will have it administered monthly and …

  • 26 views
  • 25 Oct, 2022
  • 1 location
CBT-I or Zolpidem/Trazodone for Insomnia (COZI)

This study is a randomized (1:1:1) comparative effectiveness trial of medication (zolpidem or trazodone), cognitive-behavioral therapy for insomnia (CBT-I), and the combination (medication + CBT

zolpidem
chronic insomnia
cognitive behavioral therapy for insomnia
trazodone
behavior therapy
  • 0 views
  • 05 Jul, 2022
  • 8 locations
A Single-Dose, Double-Blind, Placebo-Controlled, Randomized, Crossover Study to Determine the Abuse Potential of Single Oral Dose of Seltorexant Compared To Suvorexant and Zolpidem

The purpose of this study is to evaluate the abuse potential of seltorexant compared to placebo and two active comparators (zolpidem and suvorexant) in non-dependent, recreational sedative users

Accepts healthy volunteers
  • 0 views
  • 25 Oct, 2022
  • 1 location
A Pilot Study to Evaluate the Effects of Castration on the Pharmacokinetics of Zolpidem After Single Dose Administration in Men With Prostate Cancer Undergoing Androgen Deprivation Therapy Compared to Normal Healthy Females

Background Insomnia is associated with difficulty sleeping. The drug zolpidem is widely prescribed for insomnia. Women have reported worse effects from the drug

cancer treatment
testosterone
blood test
neutrophil count
antiandrogen therapy
  • 5 views
  • 22 Oct, 2022
  • 1 location
Treatment of Disturbed Sleep in Progressive Supranuclear Palsy (PSP)

: suvorexant- which targets a wake promoting system, zolpidem- a standard hypnotic that engages sleep promoting systems, versus placebo. Each condition will last 1 week and will be separated by a 1 week

  • 24 views
  • 10 May, 2022
  • 1 location
Partial Reinforcement II: Three Approaches to Maintenance Therapy for Chronic Insomnia (R01)

The study is a three phase sequential study of the medical treatment of insomnia with zolpidem. All participating subjects will receive one month of standard nightly treatment. If the subject

zolpidem
chronic insomnia
cbt-i
cognitive behavioral therapy for insomnia
behavior therapy
  • 60 views
  • 04 Oct, 2022
  • 1 location
Interest of Auriculotherapy in the Management of Chronic Insomnia (AURICULO-DODO)

The aim of the study is to show that auriculotherapy is effective in the treatment of chronic insomnia.

chronic insomnia
  • 4 views
  • 25 Mar, 2022
  • 2 locations
Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment (CSA)

Central sleep apnea (CSA) is common in patients with heart failure and those using opioid analgesics. Unfortunately, effective treatment of central apnea remains elusive, pressure therapy given the modest efficiency of positive airway pressure therapy. The focus of this proposal is to identify mechanistic pathways to guide future therapeutic interventions …

opioid
heart failure
apnea-hypopnea index
central sleep apnea
Accepts healthy volunteers
  • 35 views
  • 23 Mar, 2022
  • 1 location
Confirm the Effectiveness of Predictix Genetics Antidepressant -Guided Treatment in Adults With MDD

A randomized, controlled, prospective, multicenter, patient and rater blinded study with 2 arms: Treatment as Usual (TAU) and Predictix Guided Treatment (PGT). The study will compare the rate of treatment response and remission among both groups; TAU vs PGT.

  • 0 views
  • 07 Dec, 2021
  • 4 locations