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Found 7 clinical trials
Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression

Asymptomatic men without pain due to prostate cancer progressing with metastatic CRPC after treatment with combination or sequential ADT + Abi will be treated on a randomized, open label study to determine if sequential treatment with high dose T and Enza will improve primary and secondary objectives vs. continuous Enza …

  • 0 views
  • 14 Feb, 2021
  • 1 location
Goserelin Acetate Sustained Release Microspheres Injection LY01005 for Prostate Cancer

This is a multicenter, randomized and open label Phase Clinical Study, comparing the efficacy and safety of LY01005 with Zoladex in patients with prostate cancer.

  • 0 views
  • 25 Jan, 2021
  • 1 location
Androgen Deprivation Therapy Muscle Protein Metabolism and Blood Glucose

Prostate cancer (PCa) patients receiving androgen deprivation therapy (ADT) (e.g., Zoladex), experience troublesome side effects during and after treatment (e.g., loss of lean body mass (LBM

androgens
insulin
antiandrogen therapy
androgen suppression
zoladex
  • 45 views
  • 22 Jan, 2021
  • 1 location
Nivolumab + Docetaxel + ADT in mHSPC Patients With DDRD or Inflamed Tumors

study drugs involved in this study are: Androgen deprivation therapy (ADT) with a drug of your physician's choice. This may include leuprolide (Lupron), goserelin acetate (Zoladex), or

gilbert's syndrome
leuprolide
bone metastases
neutrophil count
endocrine therapy
  • 0 views
  • 22 Mar, 2021
Pilot Study of the IL-1 Antagonist Anakinra for the Treatment of Endometriosis Related Symptoms

All current FDA approved medications to treat endometriosis pain including danazol, GnRH agonists (Lupron, Zoladex and Synarel), GnRH antagonist (elagolix) and depo-provera prevent or contradict

dysmenorrhea
elagolix
gnrh antagonist
zoladex
endometriosis
  • 93 views
  • 24 Jan, 2021
  • 1 location
RE-sensitizing With Supraphysiologic Testosterone to Overcome REsistance (The RESTORE Study)

Single-arm, single site, open label study of the effects of parenteral testosterone followed by enzalutamide, abiraterone or castration-only therapy in men with metastatic CRPC who previously progressed on one of these forms of therapy. The study will enroll four cohorts of patients: men with metastatic CRPC who have progressed on …

bicalutamide
adenocarcinoma
cabazitaxel
arn-509
enzalutamide
  • 14 views
  • 25 Jan, 2021
  • 2 locations
Study of Preservation of Ovarian Reserve During Chemotherapy for Young Breast Cancer Patients

The purpose of this study is to assess efficacy of gonadotropin-releasing hormone agonist (goserelin) on the preservation of ovarian reserve function in breast cancer patients of reproductive age treated with (neo)adjuvant chemotherapy by serial measuring ovarian reserve markers (AMH and AFC.etc) before and after chemotherapy.

breast cancer staging
mammogram
early-stage breast cancer
gonadotropin releasing hormone
immunostimulant
  • 0 views
  • 25 Jan, 2021
  • 1 location