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Found 57 clinical trials
9-ING-41 in Patients With Advanced Cancers

GSK-3β is a potentially important therapeutic target in human malignancies. The Actuate 1801 Phase 1/2 study is designed to evaluate the safety and efficacy of 9-ING-41, a potent GSK-3β inhibitor, as a single agent and in combination with cytotoxic agents, in patients with refractory cancers.

metastatic malignancy
HER2
amylase
lomustine
kidney function tests
  • 795 views
  • 15 May, 2022
  • 10 locations
The Impact of Infant Formula With Probiotics on Infants Health

The trial will be divided into three groups, the experimental group: (I) probiotic A formula, (II) probiotic B formula; control group: (III) regular formula (Youluck infant formula). Inclusion criteria included: (1) the normal spontaneous delivery (NSD) full-term health infants (≧37 weeks) and birth weight more than 2500 grams and (2) …

Accepts healthy volunteers
  • 0 views
  • 05 May, 2022
  • 1 location
School-Based Nutrition Education in Improving Dietary Diversity Among Adolescent Girls

The investigators hypothesize that school-based nutrition education will increase dietary diversity among the adolescent girls. The investigators propose a matched, pair-cluster randomized controlled trial to measure the efficacy of school-based nutrition education on dietary diversity of the adolescent girls in Bangladesh. This study will have two arms (one intervention and …

folic acid
nutrition education
iron
Accepts healthy volunteers
  • 1 views
  • 07 Apr, 2022
  • 1 location
Impact of Pancreatic Endoscopic Drainage on Exocrine Pancreatic Function in Unresectable Pancreatic Cancer (DEPARA)

Background: exocrine pancreatic insufficiency (IPE), frequent in patients with pancreatic cancer, plays a major role in malnutrition and cachexia with a significant impact on survival, quality of life and tumor progression. IPE due to obstruction of the main pancreatic duct and atrophy of pancreatic parenchyma proximal to the tumor could …

  • 0 views
  • 22 Mar, 2022
  • 1 location
Tooth Retention After Root Canal Treatment With Endomethasone N (ENDO2021-02)

examinations. Different families of root canal sealers are used in endodontics: cements based on zinc oxide-eugenol (ZOE), resin-based materials, and calcium silicate-based cements. They provide a

  • 0 views
  • 23 Mar, 2022
  • 5 locations
Mineral Status in Pregnant Women (PREDISH)

and psychomotor development. In women of procreative age, an adequate supply of minerals, especially iron, calcium, zinc, magnesium and copper, is very important. The results of clinical trials

Accepts healthy volunteers
  • 4 views
  • 22 Apr, 2022
  • 1 location
Detection of High Expression Levels of EMT-Transcription Factor mRNAs in Patients With Pancreatic Cancer and Their Diagnostic Potential

The present study is aimed at detecting and measuring mRNA levels of genes involved in epithelial to mesenchymal transition (EMT) in biological samples, i.e. in peripheral blood samples of pancreatic cancer (PC) patients and healthy controls, to determine the presence of disease, its progression and risk of recurrence.

carcinoma
Accepts healthy volunteers
  • 2 views
  • 02 Mar, 2022
  • 1 location
Immune Cell Response to Stimuli

This study will investigate the response of immune cells (neutrophils, monocytes) to various signals in the test tube to determine how they sense the signals in the body and what substances they produce in response to them. It will determine how the cells may, under certain circumstances, contribute to inflammation, …

leukocyte count
monocytes
Accepts healthy volunteers
  • 282 views
  • 11 May, 2022
  • 1 location
International Milk Composition (IMiC) Consortium (IMiC)

The IMiC Consortium will analyze milk from 1000 mother-infant dyads across 4 diverse settings (Tanzania, Pakistan, Burkina Faso and Canada). Samples will be stored centrally at the Manitoba Interdisciplinary Lactation Centre (MILC) biorepository and distributed to multiple laboratories for analysis of macronutrients, micronutrients, oligosaccharides, growth factors, immunoglobulins, cytokines, metabolites and …

  • 0 views
  • 26 Mar, 2022
  • 1 location
Observational Study for Patients With Hemoglobinopathies and Rare Inherited Anemia and Covid 19

The COVID-19 pandemic is causing many deaths around the world, putting a strain on health services. Patients with pre-existing chronic conditions are most affected by the SARS-COV2 infection. Infectious complications are a common cause of mortality and one of the main causes of morbidity in all these diseases. The main …

  • 0 views
  • 17 May, 2022
  • 2 locations