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Found 348 clinical trials
Study of Personalized Instrument in Total Shoulder Arthroplasty The P.I.T.S.A. Study (PITSA)

Total shoulder arthroplasty is an effective procedure to improve patients function and to relieve shoulder pain in cases of glenohumeral arthritis. The main challenge of this procedure is implanting the glenoid component. Indeed, surgical exposure is difficult and proper visualization of the glenoid is demanding. The current free-hand method is …

  • 29 Jun, 2022
  • 1 location
Lymphocyte Depletion and Change in Lymphocyte Functionality

Lymphocytes are a type of white blood cell (WBC) found in the participant's blood. During radiation treatment, moving blood is exposed to radiation. This may cause a decrease in the amount of lymphocytes. A researcher at UVA has created a system to predict and reduce the immune cell reduction following …

  • 28 Feb, 2022
  • 1 location
Optimizing Brachytherapy Application and Delivery With MRI Guidance for Gynecologic Cancer

The aim of this study is to develop new tools using magnetic resonance imaging (MRI) that will improve the brachytherapy procedure and treatment for participants with gynecologic cancer.

  • 16 Mar, 2022
  • 1 location
Clinical Evaluation of Vertical Inter-implant Papilla Height in Platform Matched Implants in Comparison to Morse Connection Abutments

The complete fill of the inter-implant mucosa is much more challenging between two implants, than single implants, and is considered to be unpredictable (Tymstra et al., 2011). However, previous clinical studies have pointed to a relationship between the inter-implant mucosa fill and the horizontal distance between two adjacent implants. In …

  • 26 Sep, 2021
  • 1 location
Cam Decompression Utilizing the Stryker Hip-Check Software Platform

Accurate femoroplasty has been shown to be critical in achieving success following treatment of femoroacetabular impingement (Matsuda, Schnieder, and Sehgal 2014; Mansor et al. 2018; Larson et al. 2014). Nearly 75% of cases undergoing revision hip arthroscopy do so due to residual femoroacetabular impingement (Ricciardi et al. 2014). Femoroplasty remains …

  • 28 Aug, 2021
  • 1 location
Post-Operative Kinesio Taping Impact on Pain in Thoracotomy vs Thoracoscopy

The project is of a comparative nature. It seeks to study pain reduction following two forms of chest surgery and compare results between both procedures. It will use kinesio taping as the studied pain reducer. It will involve 4 study groups, 2 per surgical procedure, and among those 2 main …

  • 21 Mar, 2022
  • 1 location
Mandibular Reconstruction With Axially Vascularised Bone Substitutes

Mandibular reconstruction is necessary following trauma, tumour resections and extensive infections resulting in severe defects of the mandibular arch. For reconstructing large and recurrent defects, the vascularized free flaps are currently regarded as the gold standard. The use of these flaps, however, presents several major inconveniences. Although regenerative medicine in …

  • 05 Jun, 2022
  • 1 location
VR to Reduce Pain/Anxiety During Painful Procedures

This study aims to test the effectiveness of virtual reality (VR) as a non-pharmaceutical intervention to reduce pain and anxiety in children undergoing painful procedures in Phlebotomy, Radiology, Infusion, Orthopedics, Gastroenterology, and Immunology, amongst others, at CHLA, as measured by self- and proxy-report. Examples of the painful procedures include IV …

Accepts healthy volunteers
  • 19 Apr, 2022
  • 1 location
Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

by surgery. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors.

intracranial meningioma
tumor cells
step 2
ct scan
central pathology review
  • 21 Mar, 2022
  • 131 locations
Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated With Chemotherapy

previously treated with chemotherapy and surgery. Lymph node dissection may remove cancer cells that have spread to nearby lymph nodes in patients with breast cancer. Radiation therapy uses high-energy x

lobular carcinoma in situ
invasive breast cancer
  • 18 Jun, 2022
  • 5 locations