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Found 130 clinical trials
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Incorporating Nutrition Vests Education and Strength Training in Bone Health (INVEST in Bone Health)

The main goal of the proposed study is to compare the effects of weight loss (WL) alone with WL plus weighted vest use or WL plus resistance exercise training (RT) on indicators of bone health and subsequent fracture risk.

  • 108 views
  • 23 Mar, 2021
  • 1 location
None
A Comparison of Two Different Surgical Techniques in Hip Resurfacing Arthroplasty

The purpose of the study is to compare two different surgical techniques in hip resurfacing arthroplasty (RHA), comparing bloodflow and metabolism in the femoral head, as well as implant migration, periprosthetic bone mineral density, gait function and patient recovery.

bone mineral density
osteoarthritis
  • 9 views
  • 07 Nov, 2020
  • 1 location
None
Effect of Soluble Corn Fiber Supplementation for 1 Year on Bone Metabolism in Adolescents

The primary aim of this proposal is to determine the effects of soluble corn fiber (SCF) supplementation for 1 year on bone metabolism in growing adolescents compared to controls. For the proposed study, a randomized double-blinded placebo controlled clinical trial will be conducted in 236 healthy adolescents aged 10-13 years, …

calcium
bone mineral density
body mass index
  • 34 views
  • 14 May, 2021
  • 1 location
None
Comparison Between Mirtazapine and Megestrol for the Control of Anorexia-cachexia in Cancer Patients in Palliative Care.

Cancer-associated anorexia-cachexia is an insidious syndrome that has a major impact on the patient's quality of life, but is also associated with a significant reduction in survival. Despite its clinical importance, it remains a widely underestimated and untreated condition. Considering the scarcity of pharmacological measures, it is necessary to invest …

anorexia
metastatic cancer
cancer
mirtazapine
palliative care
  • 0 views
  • 24 Jan, 2021
  • 1 location
None
Healthy Body Healthy Bones After Bariatric Surgery Trial

One in three adults in the United States suffers from obesity. Bariatric surgery is an increasingly utilized and effective treatment for obesity and obesity-related comorbidities, however, the massive weight loss associated with bariatric surgery adversely affects bone leads to an increased risk of fracture. Bisphosphonate medications, such as zoledronic acid, …

bisphosphonate
osteoporosis
Accepts healthy volunteers
zoledronic acid
  • 0 views
  • 19 Nov, 2021
  • 1 location
None
Dental Implants Rehabilitation in Patients With Vitamin D3 Imbalance

Interventional retrospective prospective randomized clinical trial (RCT) in parallel groups. The sample size is 384 patients with loss of teeth and vitamin D imbalance. All patients will undergo or underwent dental implantation after additional investigations which reveal vitamin D imbalance (<30 ng/ml or <75 nmol/l). The 1 group will include …

  • 0 views
  • 15 May, 2021
  • 2 locations
None
Treatment of Osteogenesis Imperfecta With Parathyroid Hormone and Zoledronic Acid

Osteogenesis imperfecta (OI) is an inherited skeletal disorder characterised by increased risk of fragility fractures. Bisphosphonates are frequently prescribed for adult patients with OI with the aim of preventing fractures but the evidence base for efficacy is poor. Recent evidence suggests that the bone anabolic agent teriparatide (TPTD) increases bone …

bone mineral density
zoledronic acid
parathyroid hormone
teriparatide
care adult
  • 156 views
  • 22 Jan, 2021
  • 24 locations
None
Cardiovascular Risk and Chronic Inflammatory Rheumatism

Chronic inflammatory rheumatism and inflammation can increase the risk of cardiovascular problems. Indeed, these diseases can increase the risk of myocardial infarction. The objective of this project is a better understanding and preventing the risk of cardiovascular problems in chronic inflammatory rheumatism through the study on the long-term flexibility of …

rheumatism
NSAID
psoriatic arthritis
tumor necrosis factor
biological treatment
  • 6 views
  • 21 Jan, 2021
None
Long-term Consumption of Resistant Starch Type-4 (RS4)

The primary objective of the current proposal is to determine the effectiveness of long-term consumption of Fibersym RW for improving blood lipids (including cholesterol) and body composition. The overall goal of this clinical research is to determine the potential effects that RS4 consumption may have on the prevention of obesity …

cholesterol measurement
LDL Cholesterol
blood lipids
  • 8 views
  • 11 Apr, 2021
  • 2 locations
None
Targeting Risk Factors for Diabetes in Subjects With Normal Blood Cholesterol Using Omega-3 Fatty Acids

Every 3 minutes a new case of diabetes is diagnosed in Canada, mostly type 2 diabetes (T2D) increasing the risk for heart disease. T2D and heart disease share many common risk factors such as aging, obesity and unhealthy lifestyle. Paradoxically however, while lowering blood LDL, commonly known as "bad cholesterol", …

heart disease
omega-3 fatty acids
fish oil
hmg-coa reductase inhibitors
diabetes
  • 0 views
  • 09 Sep, 2021
  • 1 location