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Found 130 clinical trials
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Romosozumab in Women With Chronic SCI

This two-year open-label pilot clinical trial will evaluate the efficacy and safety of romosozumab to treat bone loss in females with chronic spinal cord injury (SCI) and osteoporosis (OP). Participants will receive monthly injections of romosozumab during the first 12 months of the study. During the second year, participants will …

  • 0 views
  • 15 Mar, 2021
  • 1 location
None
Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury

This pilot study will determine the feasibility of implementing a combinatory rehabilitation strategy involving testosterone replacement therapy (TRT) with locomotor training (LT; walking on a treadmill with assistance and overground walking) in men with testosterone deficiency and walking dysfunction after incomplete spinal cord injury. The investigators hypothesize that LT+TRT treatment …

replacement therapy
testosterone level
locomotor training
anemia
spinal cord
  • 0 views
  • 12 Sep, 2021
  • 2 locations
None
Evaluation and Management of Metabolic Bone Disease in Kidney Transplant Recipients

There is a well-documented increased risk for disordered mineral bone homeostasis in Kidney Transplant Recipients (KTRs) when compared to the general population, leading to a markedly increased risk for fragility fractures and their associated morbidity and mortality. A more uniform and rigorous evaluation of bone and mineral homeostasis,than is afforded …

metabolic bone disease
kidney transplant
  • 1 views
  • 26 Jan, 2021
  • 1 location
None
Coral Calcium's Effect on Bone Density in Postmenopausal Women With and Without Ibandronate

This study will investigate the effect of coral calcium complex supplementation on BMD of osteoporotic individuals either when used alone or in combination with ibandronate. Ibandronate alone will also be tested in comparison to coral calcium supplementation alone or in combination.

bone mineral density
calcium supplementation
calcium
cholecalciferol
ibandronate
  • 54 views
  • 24 Jan, 2021
  • 1 location
None
Skeletal Health and Bone Marrow Composition Among Youth

Children and adolescents experiencing gender dysphoria feel increased distress with the onset of puberty. Gender clinics treat these young adolescents by "blocking" puberty using gonadotropin-releasing hormone (GnRH) agonist medications. This has the possibility of impacting bone development as sex steroids are important to bone mass development. In this multi-site study, …

  • 0 views
  • 04 Sep, 2021
  • 1 location
None
The Influence of Time-Restricted Eating in Patients Metabolic Syndrome

In a randomized controlled trial, the investigators intend to measure the health impact of TRE in patients with metabolic syndrome (with three or more of the following criteria: increased waist circumference, abnormal cholesterol levels, elevated blood pressure, or elevated blood sugar), who habitually eat for more than 14 hours every …

diabetes
fasting
statin
hdl cholesterol
hypertension
  • 10 views
  • 28 Jun, 2021
  • 1 location
None
Evaluation of Intra-Abdominal Fat Extraction Using HydraSolve T2D in Obese Subjects With Type 2 Diabetes

This study will investigate the safety and efficacy of the investigational use of the HydraSolve T2D System in improving blood glucose control and insulin resistance in patients with obesity (Class 1, BMI 30-39.9 kg/m2) and type 2 diabetes who have not achieved targeted levels of blood glucose control using oral …

insulin resistance
insulin treatment
  • 997 views
  • 26 Mar, 2021
  • 1 location
None
Evaluation of Ovarian Morphology and Function in Overweight Women During Weight Loss

The objective of this study is to explore the effects of weight loss on body composition, metabolic status, reproductive hormones, and ovarian follicle development in obese women with regular menstrual cycles versus obese women with irregular menstrual cycles and/or polycystic ovary syndrome (PCOS).

reproductive hormones
polycystic ovary syndrome
regular menstrual cycles
insulin
hormonal contraception
  • 247 views
  • 26 Jan, 2021
  • 1 location
None
Effect of Weight Loss on Body Composition and Metabolic Function in Women With Lipedema

Lipedema is a disorder characterized by massive, bilateral accumulation of fat below the waist and in the legs. Enlargement of the lower extremities is often accompanied by leg pain and accumulation of fluid. Little is known about the functional changes that lead to fat accumulation and pain in women with …

Accepts healthy volunteers
  • 316 views
  • 25 Nov, 2021
  • 1 location
None
Beetroot Supplementation in Women Enjoying Exercise Together

This study seeks to determine the feasibility of an exercise training progression with the consumption of beetroot juice or placebo prior to exercise in postmenopausal women. Results from this investigation will be used to determine preliminary effect sizes for exercise training only (control), exercise training + placebo (EX+PL), and exercise …

body mass index
beetroot juice
  • 87 views
  • 25 Jan, 2021
  • 1 location