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Found 118 clinical trials
Metabolic Adaptations in Response to High Intensity Interval Training in Obese Adults (HT)

The overall objectives are to: Assess mechanisms underlying HIIT-induced improvements in insulin resistance at the whole-body, tissue, and cellular levels. Systematically compare different HIIT regimens to help identify effective "doses" of HIIT that may be optimal for improving metabolic health in obese adults. Assess the ability/willingness of obese subjects to …

insulin resistance
glucose concentration
body mass index
  • 27 Apr, 2022
  • 1 location
The Influence of Time-Restricted Eating in Patients With Metabolic Syndrome (TIMET)

In a randomized controlled trial, the investigators intend to measure the health impact of TRE in patients with metabolic syndrome (with three or more of the following criteria: increased waist circumference, abnormal cholesterol levels, elevated blood pressure, or elevated blood sugar), who habitually eat for more than 14 hours every …

blood pressure diastolic
metabolic syndrome
  • 25 Mar, 2022
  • 1 location
A Clinical Trial Investigating the Effect of Salmon Bone Meal on Bone Mass Among Osteopenic Women

The purpose of this study is to evaluate the efficacy of salmon bone meal in preventing bone loss among perimenopausal women with reduced bone mass density.

Accepts healthy volunteers
  • 10 Oct, 2021
  • 2 locations
Evaluation of Ovarian Morphology and Function in Overweight Women During Weight Loss

The objective of this study is to explore the effects of weight loss on body composition, metabolic status, reproductive hormones, and ovarian follicle development in obese women with regular menstrual cycles versus obese women with irregular menstrual cycles and/or polycystic ovary syndrome (PCOS).

Accepts healthy volunteers
regular menstrual cycles
reproductive hormones
  • 04 Mar, 2022
  • 1 location
Coral Calcium's Effect on Bone Density in Postmenopausal Women With and Without Ibandronate

This study will investigate the effect of coral calcium complex supplementation on BMD of osteoporotic individuals either when used alone or in combination with ibandronate. Ibandronate alone will also be tested in comparison to coral calcium supplementation alone or in combination.

bone mineral density
Accepts healthy volunteers
calcium supplementation
  • 02 Mar, 2022
  • 1 location
Romosozumab in Women With Chronic SCI

This two-year open-label pilot clinical trial will evaluate the efficacy and safety of romosozumab to treat bone loss in females with chronic spinal cord injury (SCI) and osteoporosis (OP). Participants will receive monthly injections of romosozumab during the first 12 months of the study. During the second year, participants will …

spinal cord injury
vitamin d
fragility fracture
  • 25 Mar, 2022
  • 1 location
Evaluation and Management of Metabolic Bone Disease in Kidney Transplant Recipients

There is a well-documented increased risk for disordered mineral bone homeostasis in Kidney Transplant Recipients (KTRs) when compared to the general population, leading to a markedly increased risk for fragility fractures and their associated morbidity and mortality. A more uniform and rigorous evaluation of bone and mineral homeostasis,than is afforded …

metabolic bone disease
kidney transplant
Accepts healthy volunteers
  • 08 Feb, 2022
  • 1 location
Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury

This pilot study will determine the feasibility of implementing a combinatory rehabilitation strategy involving testosterone replacement therapy (TRT) with locomotor training (LT; walking on a treadmill with assistance and overground walking) in men with testosterone deficiency and walking dysfunction after incomplete spinal cord injury. The investigators hypothesize that LT+TRT treatment …

locomotor training
testosterone level
replacement therapy
  • 12 Sep, 2021
  • 2 locations
Effect of Weight Loss on Body Composition and Metabolic Function in Women With Lipedema (Lipedema)

Lipedema is a disorder characterized by massive, bilateral accumulation of fat below the waist and in the legs. Enlargement of the lower extremities is often accompanied by leg pain and accumulation of fluid. Little is known about the functional changes that lead to fat accumulation and pain in women with …

Accepts healthy volunteers
  • 09 Apr, 2022
  • 1 location
Incorporating Nutrition, Vests, Education, and Strength Training in Bone Health (INVEST in Bone Health) (INVEST)

The main goal of the proposed study is to compare the effects of weight loss (WL) alone with WL plus weighted vest use or WL plus resistance exercise training (RT) on indicators of bone health and subsequent fracture risk.

  • 13 Mar, 2022
  • 1 location