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Found 130 clinical trials
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Colchicine to Suppress Inflammation and Improve Insulin Resistance in Adults and Adolescents With Obesity

> Participants will be screened with the following: Medical history Physical exam Fasting blood tests Urine tests Electrocardiogram Dual energy x-ray absorptiometry

fatty acids
insulin resistance
sugars
oral glucose tolerance test
body mass index
  • 0 views
  • 25 Nov, 2021
  • 1 location
None
Safety Tolerability Pharmacokinetics and Pharmacodynamics of Long-term Mitapivat Dosing in Subjects With Stable Sickle Cell Disease: An Extension of a Phase I Pilot Study of Mitapivat

heart and lung function. They will have dual-energy X-ray absorptiometry scans to measure bone health. They will complete online questionnaires that measure their overall health and well-being.

a hemoglobin
acute pain
electrophoresis
absolute neutrophil count
glomerular filtration rate
  • 0 views
  • 05 Dec, 2021
  • 1 location
None
CaREFREE Study (Calorie Restriction Environment and Fitness: Reproductive Effects Evaluation Study)

: Participants fast overnight before the test. They lie on their back under a canopy for a half hour. Body composition test: This is done with a dual energy x-ray absorptiometry (DXA

Accepts healthy volunteers
  • 113 views
  • 03 Nov, 2021
  • 1 location
None
Effect of Zoledronic Acid on Prevention of Bone Loss in Acute Phase First-ever Stroke Patients

properties are similar to that of zoledronic acid. Subjects undergo a bone density (BMD-Spine and femur, Whole Body Composition Assessment) test using DEXA (dual energy x-ray absorptiometry) through

  • 0 views
  • 28 Jan, 2021
  • 1 location
None
Sex Differences in Muscle Damage Following Resistance Exercise With or Without Milk Protein Ingestion

participate in this randomised controlled trial. Maximal leg strength and body composition (by dual-energy X-ray absorptiometry; DXA) will be conducted at baseline. In females, all primary outcome measures

Accepts healthy volunteers
  • 0 views
  • 04 Nov, 2021
  • 1 location
None
Phenotyping Genetic Risk for Type 2 Diabetes

This study tests the hypothesis that non-diabetic individuals with a high genetic risk score for type 2 diabetes have impaired glucose tolerance and insulin resistance compared to those with a low genetic risk score for type 2 diabetes.

insulin resistance
impaired glucose tolerance
  • 12 views
  • 25 Jan, 2021
  • 2 locations
None
Haemophilia and Bone Loss - PHILEOS Study

Haemophilia is a rare bleeding disorder, characterized by factor VIII (HA) or factor IX (HB) deficiency. The absence or the reduction of fVIII or fIX result in impaired thrombin generation and clot formation, causing excessive bleeding (mainly haemarthrosis). Osteoporosis is a systemic bone disease characterized by a low bone mineral …

clot
deficiency
severe haemophilia a
factor ix
hemarthrosis
  • 15 views
  • 05 Dec, 2021
  • 19 locations
None
Evaluation and Management of Metabolic Bone Disease in Kidney Transplant Recipients

There is a well-documented increased risk for disordered mineral bone homeostasis in Kidney Transplant Recipients (KTRs) when compared to the general population, leading to a markedly increased risk for fragility fractures and their associated morbidity and mortality. A more uniform and rigorous evaluation of bone and mineral homeostasis,than is afforded …

metabolic bone disease
kidney transplant
  • 1 views
  • 26 Jan, 2021
  • 1 location
None
Evaluation of Intra-Abdominal Fat Extraction Using HydraSolve T2D in Obese Subjects With Type 2 Diabetes

This study will investigate the safety and efficacy of the investigational use of the HydraSolve T2D System in improving blood glucose control and insulin resistance in patients with obesity (Class 1, BMI 30-39.9 kg/m2) and type 2 diabetes who have not achieved targeted levels of blood glucose control using oral …

insulin resistance
insulin treatment
  • 263 views
  • 26 Mar, 2021
  • 1 location
None
The Influence of Time-Restricted Eating in Patients Metabolic Syndrome

In a randomized controlled trial, the investigators intend to measure the health impact of TRE in patients with metabolic syndrome (with three or more of the following criteria: increased waist circumference, abnormal cholesterol levels, elevated blood pressure, or elevated blood sugar), who habitually eat for more than 14 hours every …

blood pressure diastolic
statin
hypertension
plasma glucose
cholesterol level
  • 10 views
  • 28 Jun, 2021
  • 1 location