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Found 118 clinical trials
Renal Function Assessment in the Elderly Using Plasma Creatinine Assay and Lean Body Mass Measurement

and, henceforth, a lower SCr value, which gives an overestimation of eGFR. Muscular mass is closely linked to lean body mass (LBM), which can be properly assessed by whole-body dual X-ray

  • 0 views
  • 24 Jun, 2021
  • 1 location
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Long-term Mitapivat Dosing in Subjects With Stable Sickle Cell Disease: An Extension of a Phase I Pilot Study of Mitapivat

heart and lung function. They will have dual-energy X-ray absorptiometry scans to measure bone health. They will complete online questionnaires that measure their overall health and well-being.

blood transfusion
platelet count
hemolysis
glomerular filtration rate
absolute neutrophil count
  • 0 views
  • 27 Jul, 2022
  • 1 location
The POWER BARIATRIC Trial: Physical Outcomes With Exercise Regimens on BARIATRIC Patients

mass, will be measured by a Dual-energy X-ray absorptiometry (DEXA); microbiota composition and changes will be evaluated by stool samples that will be subjected to 16S ribosomal ribonucleic acid (16s

bariatric surgery
body mass index
fasting
fats
  • 0 views
  • 22 Aug, 2021
  • 1 location
Colchicine to Suppress Inflammation and Improve Insulin Resistance in Adults and Adolescents With Obesity

> Participants will be screened with the following: Medical history Physical exam Fasting blood tests Urine tests Electrocardiogram Dual energy x-ray absorptiometry

body mass index
cardiovascular disease
insulin
a 12
electrocardiogram
  • 4 views
  • 10 Aug, 2022
  • 1 location
Effect of Zoledronic Acid on Prevention of Bone Loss in Acute Phase First-ever Stroke Patients

properties are similar to that of zoledronic acid. Subjects undergo a bone density (BMD-Spine and femur, Whole Body Composition Assessment) test using DEXA (dual energy x-ray absorptiometry) through

  • 0 views
  • 28 Jan, 2021
  • 1 location
Sex Differences in Muscle Damage Following Resistance Exercise With or Without Milk Protein Ingestion

participate in this randomised controlled trial. Maximal leg strength and body composition (by dual-energy X-ray absorptiometry; DXA) will be conducted at baseline. In females, all primary outcome measures

Accepts healthy volunteers
  • 0 views
  • 04 Nov, 2021
  • 1 location
Phenotyping Genetic Risk for Type 2 Diabetes

This study tests the hypothesis that non-diabetic individuals with a high genetic risk score for type 2 diabetes have impaired glucose tolerance and insulin resistance compared to those with a low genetic risk score for type 2 diabetes.

impaired glucose tolerance
Accepts healthy volunteers
insulin resistance
  • 12 views
  • 22 Mar, 2022
  • 1 location
Haemophilia and Bone Loss - PHILEOS Study (PHILEOS)

Haemophilia is a rare bleeding disorder, characterized by factor VIII (HA) or factor IX (HB) deficiency. The absence or the reduction of fVIII or fIX result in impaired thrombin generation and clot formation, causing excessive bleeding (mainly haemarthrosis). Osteoporosis is a systemic bone disease characterized by a low bone mineral …

clot formation
clot
deficiency
Accepts healthy volunteers
hemarthrosis
  • 15 views
  • 11 Jul, 2022
  • 16 locations
Treatment With Romosozumab to Improve Bone Mineral Density and Architecture in Chronic SCI

The objective of the proposed work is to determine whether administration for 12 months of romosozumab (evenity) followed by 12 months of denosumab (prolia) will maintain bone mass at the knee in subjects with chronic SCI.

spinal cord injury
bone mineral density
denosumab
spinal cord disorder
spinal cord
  • 0 views
  • 21 Apr, 2022
  • 2 locations
Skeletal Health and Bone Marrow Composition Among Youth

Children and adolescents experiencing gender dysphoria feel increased distress with the onset of puberty. Gender clinics treat these young adolescents by "blocking" puberty using gonadotropin-releasing hormone (GnRH) agonist medications. This has the possibility of impacting bone development as sex steroids are important to bone mass development. In this multi-site study, …

  • 0 views
  • 04 Sep, 2021
  • 1 location