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Found 118 clinical trials
Molecular Transducers of Physical Activity Consortium (MoTrPAC) - Pediatric Protocol (MoTrPAC)

The goal of the Molecular Transducers of Physical Activity Consortium (MoTrPAC) is to assess molecular changes that occur in response to physical activity (PA). To achieve this aim, studies will be conducted in adults and separately in children and adolescents. The UC Irvine MoTrPAC Pediatric Clinical Center oversees two interrelated …

  • 0 views
  • 08 Jul, 2022
  • 1 location
Feasibility of Low Energy Diet in HFpEF and Type 2 Diabetes (ALLEVIATE)

Open, Single arm intervention, feasibility study

  • 0 views
  • 09 Jun, 2022
  • 1 location
Muscle Stimulation for Physical Function During Stem Cell Transplant

Some blood, bone marrow, and lymphatic (hematologic) cancers such as Hodgkin/Non-Hodgkin lymphomas, chronic lymphocytic leukemia, and multiple myeloma, are over-represented in Veterans due to exposures including Agent Orange and an increased percentage of patients of African American ethnicity. Hematologic transplantation (HCT) is a common treatment for these cancers, but often …

  • 0 views
  • 14 May, 2022
  • 1 location
Combining a Mediterranean Diet With Physical Activity to Address Cardiometabolic Risk

There is little doubt scientifically that healthy eating, such as adhering to the Mediterranean diet (MedDiet) principles, is key for the prevention of cardiovascular disease (CVD). There is also convincing evidence for a strong inverse relationship between moderate intensity physical activity (PA) and mortality. Surprisingly, no study has yet formally …

  • 11 views
  • 24 Jan, 2021
  • 1 location
Trochanteric Femur Fracture Operated With Dynamic Hip Screw System (DHS) Augmented With a Biphasic Apatite Sulphate Combined With Systemic or Local Bisphosphonate

The purpose of this study is to study the process of bone regeneration around a metal device in the femoral neck canal using a synthetic bone substitute Cerament bone void filler (BVF) and bisphosphonate (Zometa) locally or systemically that affects bone metabolism. Furthermore, fracture healing and implant migration will be …

  • 0 views
  • 25 Mar, 2022
  • 1 location
Exercise and Nutrition for Healthy AgeiNg (ENHANce)

The aim of this randomized placebo-controlled 5-arm clinical trial is to evaluate the effect of combined anabolic interventions compared to single or placebo interventions on physical performance in community-dwelling (pre)sarcopenic elderly ( 65 years) and to determine the underlying mechanisms of action. Important secondary outcome measures are muscle mass, muscle …

protein supplement
omega-3 fatty acids
fatty acids
heart failure
nutritional supplementation
  • 1 views
  • 13 Feb, 2022
  • 1 location
The Effects of Ketogenic Diet on the Heart and Brain

A ketogenic diet consists of a high intake of fats and a limited intake of carbohydrates, which causes an increased level of ketone bodies in the body. In recent years, it has been shown that the diet has cardiovascular protective effects. The investigators have also shown that ketone bodies act …

  • 0 views
  • 27 Aug, 2021
  • 1 location
Evaluation of a New Screening Method for Sarcopenia in Rheumatoid Arthritis

Evaluation of a new screening method for sarcopenia in rheumatoid arthritis

  • 0 views
  • 05 Sep, 2021
  • 1 location
Nutritional Stimulation of Muscle Protein Synthesis and Metabolic Rate After Bariatric Surgery

Bariatric surgery is an effective treatment for severe obesity but results in loss of muscle mass. The investigators will test the hypothesis that consumption of an Essential Amino Acid-based nutritional formulation will maintain muscle mass while stimulating fat loss after bariatric surgery.

bariatric surgery
protein supplement
sleeve gastrectomy
roux-en-y
  • 4 views
  • 21 Mar, 2022
  • 1 location
PTH Analog Type II Odontoid Fracture

This is a prospective cohort study with a historical control group involving patients >=50 years-old with an acute (<3 weeks) Anderson & D'Alonzo type II dens fractures identified on cervical spine CT scan. This will be a pilot efficacy trial to compare treatment of odontoid fractures with 8 weeks of …

  • 0 views
  • 12 Jul, 2022
  • 1 location