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Found 267 clinical trials
Featured trial
Duke Clinical Rsearch Unit Research Volunteer Registry

Duke Clinical Rsearch Unit Research Volunteer Registry

  • 23 Nov, 2020
  • 1 location
SC IL-1Ra in SAH - Phase III Trial (SCIL) (SCIL)

, patients will be randomised to receive either IL-1Ra or placebo for a maximum of 21 days from onset of symptoms. Patients who are found to be non-aneurysmal following randomisation will be withdrawn from

  • 11 Feb, 2022
  • 11 locations
Adapting Treatment to the Tumor Molecular Alterations for Patients With Advanced Solid Tumors: MyOwnSpecificTreatment

will discontinue the targeted therapy and will be withdrawn from study and oriented towards standard treatments patients with a stable disease at 12 weeks will be randomized in order to

  • 22 Sep, 2021
  • 14 locations
Open Label Randomized Clinical Trial to Assess the Safety of Teleconsultation

conducted on a per-protocol study sample, which will include all participants who have finished the study and have not been withdrawn because of non-allowed visits using modalities other than scheduled.

  • 01 Dec, 2021
  • 3 locations
Treatment of Hemochromatosis

This study will evaluate the effectiveness of a test called MCV in guiding phlebotomy (blood drawing) therapy in patients with hemochromatosis an inherited disorder that causes too much iron to be absorbed by the intestine. The excess damages body tissues, most severely in the liver, heart, pancreas and joints. Because …

Accepts healthy volunteers
  • 14 May, 2022
  • 1 location
Impact of SFV of Proximal Colon on ADR

To evaluate the impact of second forward view examination of the proximal colon on adenoma detection rate Inclusion criteriaPatients 18 years of age undergoing screening, follow-up monitoring, and diagnostic colonoscopy Exclusion criteriaCecal intubation failed. Have a history of colorectal surgery. Insufficient bowel preparation, Boston Bowel Preparation Score (BBPS) <6 points. …

  • 23 Jul, 2021
  • 1 location
Outcome Research to Confirm the Anti-anginal Effect of T89 in Patients With Stable Angina

This is a multi-center, double-blind, randomized, placebo-controlled, parallel-group phase 3 clinical study to confirm the safety and efficacy of T89 in patients with stable angina pectoris, with an extended open-label period to evaluate the long-term safety of T89. This study includes three main periods: the first study period is a …

  • 04 Mar, 2022
  • 1 location
PD1 Combined With Chemotherapy for Adjuvant Treatment of Gastric Cancer

"This is an international, multicenter, randomized, double-blind phase III study, plans to recruit 680 patients who received radical gastrectomy (R0, D2 or higher lymphadenectomy) with postoperative pathological stage II (T4aN0M0) or III (the 8th Edition American Joint Committee on Cancer [AJCC] Cancer Staging Manual) gastric adenocarcinoma and gastroesophageal junction adenocarcinoma, …

  • 22 Apr, 2022
  • 4 locations
Effects of High FIO2 on Post-ERCP Pancreatitis.

Post-ERCP pancreatitis is one of the most common complications accounting for substantial morbidity and mortality. The incidence of post-ERCP pancreatitis (PEP) has been studied in several large clinical trials and ranges from 1.6-15%. However most studies have demonstrated rates around 5%. This complication alone is estimated to cost the US …

  • 29 May, 2021
  • 1 location
Gel for Early Hypoglycaemia Prevention in Preterm Infants

The GEHPPI study is a multicentre placebo controlled randomized controlled trial that aims to prevent early hypoglycaemia in preterm newborns born at 32 week's gestation. To do this we will prophylactically administer to these newborns either a small amount of dextrose 40% gel early as possible after birth via the …

Accepts healthy volunteers
  • 10 Oct, 2021
  • 5 locations