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Found 7 clinical trials
A Clinical Study to Evaluate the Use of a Cryopreserved Formulation of OTL-103 in Subjects With Wiskott-Aldrich Syndrome

encoding for the Wiskott-Aldrich Syndrome is introduced by means of a third generation lentiviral vector.

  • 0 views
  • 22 Mar, 2022
  • 2 locations
  • 6 views
  • 04 Mar, 2022
  • 1 location
Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies

This is a standard of care treatment guideline for allogeneic hematopoetic stem cell transplant (HSCT) in patients with primary immune deficiencies.

bone marrow transplant
chediak-higashi syndrome
busulfan
griscelli syndrome
treatment guideline
  • 299 views
  • 29 Apr, 2022
  • 1 location
Immune Disorder HSCT Protocol

This study hypothesizes that a reduced intensity immunosuppressive preparative regimen will establish engraftment of donor hematopoietic cells with acceptable early and delayed toxicity in patients with immune function disorders. A regimen that maximizes host immune suppression is expected to reduce graft rejection and optimize donor cell engraftment.

stem cell transplantation
g-csf
stem cell infusion
hsct
immunosuppression
  • 125 views
  • 11 May, 2022
  • 1 location
Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer

This phase II trial studies how well fludarabine phosphate, cyclophosphamide, total body irradiation, and donor stem cell transplant work in treating patients with blood cancer. Drugs used in chemotherapy, such as fludarabine phosphate and cyclophosphamide, work in different ways to stop the growth of cancer cells, either by killing the …

carbon monoxide
flt3-itd
polycythemia vera
myelofibrosis
kostmann's syndrome
  • 134 views
  • 30 Apr, 2022
  • 1 location
Participation in a Research Registry for Immune Disorders

Background People with primary immune deficiency diseases (PIDD) have weak immune systems. This makes it hard for their bodies to fight infection. The Immune Deficiency Foundation has a network to collect data about people with PIDD. It is called the United States Immunodeficiency Network. It will help doctors and scientists …

undernutrition
primary immunodeficiency
  • 113 views
  • 06 May, 2022
  • 1 location
Studies of Skin Microbes in Healthy People and in People With Skin Conditions

syndrome), WAS (Wiskott-Aldrich syndrome), or DOCK8 immunodeficiency because they frequently have skin problems similar to AD. Eligible participants undergo the following tests and procedures:

Accepts healthy volunteers
immune disorder
serum ige
examination skin
blood test
  • 232 views
  • 12 May, 2022
  • 1 location