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Found 41 clinical trials
The Role of Meningeal Lymphatic Vessels in the Absorption of Chronic Subdural Hematoma and Its Injury Mechanism

Chronic subdural hematoma (CSDH) is a very common hemorrhagic disease of the nervous system, accounting for about 10% of hemorrhagic strokes. The incidence rate of elderly people over 65 years old is 58.1/100,000, and the incidence rate is increasing year by year, and it may reach 121/100,000 by 2030. At …

Accepts healthy volunteers
  • 0 views
  • 07 Jul, 2022
  • 1 location
Efficacy of Clopidogrel on Incidence of Silent Brain Infarction (ECISBI)

Silent brain infarctions (SBIs) are a manifestation of covert cerebrovascular disease, without obvious clinical deficit, noted very often in patients presenting with a new stroke or new transient ischemic attack. SBIs are linked to a significant increase in risk for subsequent stroke and cognitive decline. However, no biomarker is currently …

  • 0 views
  • 22 Apr, 2022
  • 1 location
Topical Vancomycin Over Sternal Edge in Cardiac Surgery

This is a single-blind 1:1 randomized controlled trial based on the hypothesis that topical application of vancomycin paste over sternum edge is safe and can reduce sternal wound infection after elective cardiac surgery. Vancomycin paste will be prepared using 2.5 g of vancomycin mixed with 2 ml normal saline. Vancomycin …

  • 0 views
  • 12 Sep, 2021
  • 1 location
Safety and Feasibility Study of Methylene Blue Photodynamic Therapy to Sterilize Deep Tissue Abscess Cavities

The objectives of this Phase 1 study are to evaluate the safety and feasibility of methylene-blue-mediated photodynamic therapy (MB-PDT) performed at the time of abscess drainage to treat deep tissue abscesses. Safety will be evaluated by physical examination and imaging and laboratory studies in order to identify adverse events that …

drainage
cavities
methylene
  • 26 views
  • 05 Apr, 2022
  • 1 location
Treatment of Ocular Demodex Infestation With Topical Ivermectin Cream 1%

Patients with Demodex infestation of the eyelids will have the sleeves from both eyes cleaned off with microblepharoexfoliation. Afterwards, one eye will be randomly selected for treatment with topical ivermectin 1% cream. The treatment will be repeated on that eye 2 weeks later. Afterwards, the patients will present monthly for …

Accepts healthy volunteers
  • 12 views
  • 24 Mar, 2022
  • 1 location
Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and Adolescents

Acute lymphoblastic leukemia (ALL) is the most common cancer diagnosed in children. The cancer comes from a cell in the blood called a lymphocyte. Normal lymphocytes are produced in the bone marrow (along with other blood cells) and help fight infections. In ALL, the cancerous lymphocytes are called lymphoblasts. They …

asparaginase
dasatinib
lymphoid leukemia
pegaspargase
corticosteroids
  • 26 views
  • 20 Jun, 2022
  • 9 locations
Blue Light Therapy in Reducing Inflammation During Sepsis

. The outcome of interest is change in the inflammatory response after surgery for appendicitis or diverticulitis as measured by the following parameters: white blood cell count, heart rate, the

pneumonia
white blood cell count
colon resection
sepsis
abscess
  • 119 views
  • 10 Mar, 2022
  • 1 location
A Phase I Study of MozobilTM in the Treatment of Patients With WHIMS

neutropenia. Objectives To evaluate whether Mozobil is safe and effective to treat neutropenia (low white blood cell count) in patients with WHIMS

HIV Infection
immune globulin
white blood cell count
bone marrow transplant
severe infection
  • 112 views
  • 14 Sep, 2022
  • 1 location
A Phase I/II Study Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients

their white blood cell count. This will be a shot or injection under the skin. Participants will recover in the hospital for 1-2 weeks. They will have lab and blood tests. Participants

fludarabine
leucovorin
systemic therapy
cancer treatment
NRAS
  • 31 views
  • 14 Sep, 2022
  • 1 location
A Phase I Study of HERV-E TCR Transduced Autologous T Cells in Patients With Metastatic Clear Cell Renal Cell Carcinoma

tube) inserted into a vein in the chest. Get the changed cells via catheter. Get a drug to increase white blood cell count and one to make the cells active. Recover for

platelet count
chemotherapy drugs
white blood cell count
tumor cells
treatment regimen
  • 73 views
  • 22 Sep, 2022
  • 1 location