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Found 440 clinical trials
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Enhanced Bioscaffold for Volumetric Muscle Loss

This is a prospective, single center study conducted at the University of Pittsburgh designed to test the applicability and utility of XenMatrix AB Surgical Graft in the restoration of function in the setting of volumetric muscle loss after soft tissue trauma.

  • 0 views
  • 27 Jan, 2021
  • 1 location
None
Vestibular Rehabilitation Verses Virtual Reality on Dizziness Balance and Gait in Subacute Stroke

There is paucity of literature in studying the comparative effects of Vestibular Rehabilitation and Virtual Reality. This study will determine the effects of these interventions on dizziness, balance and gait. This study will also deduce the role of vestibular rehabilitation and Virtual reality in subacute stroke patients

  • 0 views
  • 18 Nov, 2021
  • 1 location
None
Nutrition and Exercise in Critical Illness

This study proposes a novel early intervention combining Intravenous (IV) amino acids plus in-bed cycle ergometry exercise to improve physical outcomes in critically ill patients. The investigators hypothesize that this innovative approach will improve short-term physical functioning outcomes (primary outcome), as well as amino acid metabolism, body composition, and patient-reported …

critical illness
mechanical ventilation
  • 38 views
  • 12 Sep, 2021
  • 6 locations
None
Mechanical Insufflation -Exsufflation in Children With NMD and Weak Cough

Neuromuscular diseases (NMD) in children are severe, possibly life-threatening orphan conditions. The children are vulnerable and often subject to rapid deterioration of pulmonary function due to impaired ability to clear airway secretions. The use of mechanical cough augmentation with insufflation-exsufflation (MIE) is a strategy to treat and prevent. Possible major …

  • 0 views
  • 25 Jan, 2021
  • 4 locations
None
Altitude Related Adverse Health Effects (ARAHE) in Patients With Precapillary Pulmonary Hypertension During 30h Exposure to 2500m

The interest of journeys to high altitude regions for recreational or professional purposes is increasing, also among potentially vulnerable groups including patients with chronic cardiopulmonary diseases such as pulmonary hypertension (PH). In Switzerland and many other regions worldwide, many settlements and alpine resorts are at altitudes above 1500m and alpine …

  • 0 views
  • 11 Nov, 2021
  • 1 location
None
Adolescent Anterior Knee Pain: ARP Wave Therapy vs. Physical Therapy

Accelerated Recovery Performance (ARP) Wave therapy is an electromyostimulation therapy designed to enhance neuromuscular control in order to rehabilitate patients with musculoskeletal pathology. The outcomes of this technology have not been assessed under the rigors of clinical science. This prospective randomized crossover study will assess ARP Wave to both shorten …

neurological therapy
larsen
patellofemoral syndrome
rigors
fat pad syndrome
  • 15 views
  • 11 Feb, 2021
  • 1 location
None
Tranexamic Acid to Prevent OpeRation in Chronic Subdural Hematoma

Rationale: Chronic subdural hematoma (cSDH) is a frequently occurring disease, occurring mainly in the elderly. Surgical evacuation is effective, but also associated with life-threatening risks. In these old, often frail, patients with multi-comorbidity, surgery also comes with significant risks for future cognitive functioning and therefore, loss of independency. In five …

  • 8 views
  • 20 Jun, 2021
  • 1 location
None
The SAFE Trial. Sterile Amniotic Fluid Filtrate Epidural Injection.

There is a large population of patients with lumbosacral radicular pain due to spinal stenosis who do not respond to physical therapy or oral medication management, yet wish to avoid spinal surgery or are simply not candidates due to medical co-morbidity. Given the natural history of lumbar spinal stenosis, these …

  • 2 views
  • 23 Oct, 2021
  • 1 location
None
Efficacy of Adaptogens in Patients With Long COVID-19

The aim of this clinical trial of a fixed combination of standardized extracts from Rhodiola rosea roots, Schisandra chinensis berry and Eleutherococcus senticosus root (ADAPT-232) in COVID-19 patients is to demonstrate possible efficacy of adjuvant treatment with ADAPT-232 in decreasing the duration of the convalescence, alleviation of fatigue, headache, attention …

  • 0 views
  • 28 Sep, 2021
  • 1 location
None
A Study of TAK-079 in People With Generalized Myasthenia Gravis

Myasthenia gravis is an autoimmune condition that causes muscle weakness. Autoimmune means the body makes antibodies that attack its own cells and tissues. These types of antibodies are also

serologic test
immunosuppressive agents
cholinesterase inhibitors
tacrolimus
corticosteroids
  • 26 views
  • 02 Apr, 2021
  • 59 locations