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Found 69 clinical trials
Treatment of Post-STEMI Left Ventricular Thrombus With Optimized Anticoagulant (EARLYmyo-LVT)

Left ventricular thrombus is a common complication subsequent to ST-segment elevation myocardial infarction (STEMI) that related to increased embolic events. This study aims to assess the efficacy and safety outcomes of Rivaroxaban on the treatment of post-STEMI left ventricular thrombus.

clopidogrel
angiography
stemi
troponin
warfarin
  • 0 views
  • 01 Mar, 2022
  • 1 location
Residual Anti-Xa Activity After Last Treatment Dose of Enoxaparin

The main objective of this study is to determine the time interval following the last treatment dose of enoxaparin at which the amount of anti-Xa level activity is reliably less than 0.2IU/mL in patients presenting for elective surgery.

enoxaparin
elective surgery
  • 6 views
  • 24 Dec, 2021
  • 1 location
Phase II Trial of Disulfiram With Copper in Metastatic Breast Cancer

The aim of the study is to establish clinical evidence for introducing disulfiram and cooper as an active therapy for metastatic breast cancer upon failure of conventional systemic and/or locoregional therapies. Analyses of the following objectives will be performed in the population of patients with metastatic breast cancer: Primary efficacy …

breast cancer
biomarker analysis
metastasis
dna damage
serum copper
  • 21 views
  • 19 May, 2021
  • 1 location
Ultrasound-guided Axillary Versus Conventional Cephalic Venous Access for Implantation of Cardiac Devices

The implantation of cardiac electronic devices is a common procedure in the Electrophysiology Laboratory. The most commonly used venous access sites are the cephalic, the axillary and the subclavian vein. Studies comparing these options have been conducted in the past. Axillary venous access can be achieved either through axillary vein …

  • 0 views
  • 20 Jul, 2021
  • 1 location
EHR-Embedded Decision Support to Prevent Stroke in Patients With AF

Background and Significance - Atrial fibrillation (AF) is the most common significant cardiac rhythm disorder and is a powerful common risk factor for stroke. Randomized trials have demonstrated that anticoagulation can reduce the risk of stroke in patients with AF. Yet, there continues to be widespread underutilization of this therapy. …

atrial flutter
stroke
anticoagulant therapy
fibrillation
anticoagulation therapy
  • 0 views
  • 16 Mar, 2022
  • 1 location
New Designed ePTFE Valved Conduits for Surgical Reconstruction of Right-ventricular Outflow Tract

Valved conduits used for the reconstruction of right-ventricular outflow tract are applied in the surgical repair of complex congenital heart disease(CHD) such as pulmonary atresia(PA), truncus arteriosus, severe tetralogy of Fallot(TOF) for their significant roles in reducing pulmonary valve regurgitation and preserving right ventricle function. With a rising cases of …

pulmonary insufficiency
complex congenital heart disease
regurgitation
tetralogy of fallot
  • 0 views
  • 31 Oct, 2021
  • 3 locations
Androgen Excess as a Cause for Adipogenic Dysfunction in PCOS Women

The purpose of this research study is to collect specimen samples and study medical information from women with Polycystic Ovary Syndrome (PCOS) and women without PCOS. The goal is to learn more about the changes that take place in the body that result in PCOS. We anticipate that 32 women …

dual-energy x-ray absorptiometry
glucose tolerance test
ovarian dysfunction
Accepts healthy volunteers
hirsutism
  • 1033 views
  • 23 May, 2022
  • 1 location
SBRT in Chagas Disease Ventricular Tachycardia

This is an observational study of 10 Chagas Disease patients with Ventricular Tachycardia that have failed prior catheter ablation or have this procedure contraindicated due to clinical status. Those patients will underwent to Stereotactic Body Radiation Therapy (SBRT) targeting the area of the heart of the VT circuits. Radioablation target …

MRI
anesthesia
ventricular tachycardia
antiarrhythmic drug
heart disease
  • 0 views
  • 08 Aug, 2021
  • 1 location
Implementation of Point-of-Care Pharmacogenomic Decision Support Accounting for Minority Disparities

incorporating minority-specific pharmacogenomic information; (b) To determine whether clinical outcomes for the drug warfarin are improved in African Americans through the availability of pharmacogenomics-based

  • 2 views
  • 26 Mar, 2022
  • 1 location
Precision Medicine Platform for Novel Oral Anticoagulants

prescription of new oral anticoagulants (NOAC) has increasingly and largely replaced warfarin in accordance of better efficacy and safety, there are still adverse effects, including incidental minor and major

  • 1 views
  • 15 Feb, 2022
  • 1 location