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Found 12 clinical trials
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Long-term Mitapivat Dosing in Subjects With Stable Sickle Cell Disease: An Extension of a Phase I Pilot Study of Mitapivat

will repeat some of the screening tests during the study. Participants will complete 6-minute walk tests to measure mobility and function. They will have transthoracic echocardiograms to measure

a hemoglobin
platelet count
acute pain
  • 15 May, 2022
  • 1 location
Xeomin® and Gait Related Mobility After Stroke

The aim of the present pilot study is to evaluate the association between change in gait related mobility in ambulatory male and female adult hemiparetic patients before and 4-6-weeks after Xeomin® injection into the upper limb, using two standardized tests of physical function in outpatient rehabilitation that are widely used; …

  • 11 May, 2022
  • 1 location
CO2-Patterns During Hyperoxia and Physical Exercise in COPD

The aim of the study is to investigate a possible correlation between the change in PCO2 during a hyperoxia-test and the change in PCO2 during walking in people with COPD

  • 24 Jul, 2021
  • 1 location
Increasing Physical Activity in COPD Through Rhythmically Enhanced Music

The VA cares for nearly one million Veterans with COPD at a cost of more than $5.5 billion annually. COPD profoundly impairs quality of life as it limits ability to work, to maintain physical exertion and to engage in social activities. Hospital-based rehab can decrease the need for inpatient and …

  • 12 Mar, 2022
  • 1 location
Border Region Area Lifestyle Intervention Study for Healthy Neurocognitive Ageing Diabetes

The objective is to evaluate a culturally tailored adaptation of The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) protocol targeted for individuals with Type 2 diabetes mellitus (DM) living in the border areas of Ireland. The primary research question to be addressed is; what is the …

  • 07 Apr, 2022
  • 1 location
Pedometers and Walking Tests for Pulmonary Hypertension Patients

Concordance between walking tests and pedometer data may seem like a logical outcome for pulmonary hypertension (PH) patients. However, many individuals have discordant results: results much worse or better during an in-hospital walking test as compared to real life activity. The primary objective of this study is: to determine variables …

  • 02 Dec, 2021
  • 1 location
Muscle Wasting in Cancer (MWIC) (MWIC)

) scans (this study will not require any additional scans for patients). The Investigators also aim to assess how their muscles function, by asking them to perform walk tests and wear a physical activity

Accepts healthy volunteers
muscle wasting
  • 29 Jan, 2022
  • 1 location
Activity, Balance and COPD (ABCOPD) (ABCOPD)

This research project incorporates a series of studies to investigate the relationship between physical performance (e.g. tests of strength, balance and walking distance) and physical activity (activity measured in day to day life) in people with COPD and other chronic lung diseases.

Accepts healthy volunteers
  • 23 Apr, 2022
Comparison of Dual-Task Timed Up and Go Test (Cognitive) and 3-m Backwards Walk Test

Two balance assessment tools that have been used recently have attracted considerable attention: the Dual-Task Timed Up and Go Test (cognitive) (DTUG) and the 3-m Backward Walk Test (3MBWT). The aim of this study is to compare the psychometric properties of two clinically proven balance assessment tools.

Accepts healthy volunteers
  • 24 Mar, 2022
  • 1 location
Assessing the Reliability and Validity of 4-meter and 10-meter Walking Test

The 4-meter walk test and 10-meter walk test is currently applied to assess gait speed.These tools are frequently used in clinical trials and were also shown to be reliable measurement methods. There are ocassions where it is not possible to have a long corridor to measure gait speed. It is …

  • 07 Oct, 2021
  • 1 location