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Found 34 clinical trials
Clinical Trial of Solriamfetol for Excessive Sleepiness Related to Shift Work Disorder

In this research study the investigators want to learn more about whether the medication Solriamfetol improves daytime sleepiness in workers who start work at very early times (between 3 and 6am).

Accepts healthy volunteers
  • 04 Jun, 2022
  • 1 location
Examining Sex-based Differences in Metabolic and Mechanistic Responses to Disuse Induced Muscle Atrophy

The purpose of the proposed research is to define whether there are differences between females and males (i.e. sex-based differences) in the metabolic and mechanistic regulation of disuse-induced muscle atrophy in vivo in humans.

Accepts healthy volunteers
  • 03 Jul, 2022
  • 1 location
Sleep Intervention in Young Boys With Duchenne Muscular Dystrophy (DMD)

This project will systematically plan and evaluate the implementation of the Transdiagnostic Sleep and Circadian Intervention for youth (TranS-CY). As an early stage study, investigators will focus on recruitment strategies to reach the target population and collection of preliminary data on primary and secondary effects of the TranS-CY. Weekly remote …

muscular dystrophy
duchenne muscular dystrophy
  • 28 Jul, 2022
  • 1 location
Implementation of a 12-week Adapted Physical Activity (APA) Program in People Suffering From Chronic Insomnia.

One third of men and women are not satisfied with their sleep. A non-drug countermeasure to improve sleep in insomniacs could be adapted physical activity (APA). However, research is needed because the literature is limited and the few studies are most often based on subjective data with a great methodological …

  • 25 Apr, 2022
  • 1 location
Emergent Microsurgical Intervention in Acute Stroke Patients After Mechanical Thrombectomy Failure Trial (EMIAS)

With all of the gains that have been achieved with endovascular mechanical thrombectomy revascularization and intravenous thrombolysis logistics, there is still a subgroup of patients with salvageable brain tissue for whom persistent emergent large vessel occlusion (ELVO) portends a catastrophic outcome. Study aims to test the safety and efficacy of …

  • 25 Mar, 2022
  • 2 locations
Health Wellbeing and Performance in Law Enforcement Workers

This study aims to assess current health and fitness of law enforcement workers in various roles, and to evaluate the impact of an exercise intervention on markers on physical and mental wellbeing in this population. The intervention will consist of an exercise programme specifically targeted at improving, physical fitness and …

glycosylated hemoglobin
  • 25 Jan, 2021
  • 1 location
Effects of the Transcranial Stimulation on Prevention of Cognitive Dysfunction in Cardiac Surgery (tDCS)

Postoperative cognitive dysfunction (POCD) is a contrary event observed between 20 to 83%, especially on elderly and patients submitted to cardiac surgery. The prevention and rehabilitation on cases of POCD can improve the quality of life and decrease the mortality in surgical patients. The effect of the noninvasive cerebral stimulation, …

cognitive impairment
brain injury
heart surgery
  • 03 Mar, 2022
  • 1 location
Construal Level as a Novel Pathway for Affect Regulation and Cancer Control

The objective of the proposed research is to conduct a longitudinal experiment on the neurocognitive pathways and individual differences in high-level construal for affect regulation and smoking cessation. The population is adult smokers aged 25-55 who have tried and failed to quit multiple times and who are experiencing poverty. The …

smoking cessation
tobacco smoke
primary cancer
  • 23 Mar, 2022
  • 2 locations
Anesthesiologic Management Effect on Perioperative Outcome in Scoliosis Surgery (SCOL)

the time to wake up from general anaesthesia after hours-long surgery. BIS monitoring allows optimizing the depth of anaesthesia and leads to improve quality and interpretation of motor evoked

  • 11 Mar, 2022
  • 1 location
The Pediatric Anesthesia Quality Improvement Project (WUS)

The Study is designed to collect information about adverse events that occur in children undergoing anesthesia in participating hospitals. Demographic information will be collected on all anesthetics. An analysis of each adverse event will be performed and entered into the database. From this information we will devise strategies to prevent …

  • 27 May, 2022
  • 38 locations