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Found 479 clinical trials
Comparison of Recovery Profile After TIVA Between Remimazolam With Flumazenil and Propofol

This prospective, randomized, single-blinded study is designed to compare the recovery profile between propofol-based total intravenous anesthesia (TIVA) and remimazolam-based TIVA in patients undergoing thyroidectomy. In the remimazolam group, its antagonist, flumazenil, is administered at the end of surgery. We hypothesize that remimazolam-based TIVA antagonized by flumazenil can significantly shorten …

  • 0 views
  • 22 Mar, 2022
  • 1 location
Protein Delivery in Intermittent and Continuous Enteral Nutrition in ICU Patients (ProBoNo)

Acute skeletal muscle wasting in ICU patients is associated with functional impairment and with increased risk of death. Of what we know today, physical disability can persist up to 5 years. Adequate nutrition is the basis for an optimal recovery for ICU patients and for prevention of muscle wasting. Today, …

Accepts healthy volunteers
  • 0 views
  • 02 Jul, 2022
  • 1 location
Phase I Study of CPI-300 in Patients With Advanced Tumors

This is a prospective, open-label, single arm, non-randomized study of CPI-300 in patients with advanced tumors. CPI-300 is administered via intravenous infusion using an accelerated titration method followed by a conventional 3 + 3 study design to identify the maximum tolerated dose (MTD).

  • 0 views
  • 10 Aug, 2021
  • 2 locations
Human Absorption, Distribution, Metabolism, and Excretion Study of [14C]Adavosertib (ADME)

This is a non-randomised study in patients with advanced solid malignancies

  • 0 views
  • 03 Jun, 2022
  • 1 location
Effect of Preoperative Carbohydrate Loading on Post-operative Insulin Resistance After Donor Hepatectomy.

It's a randomized control trial to compare the effect of preoperative carbohydrate loading versus fasting on post operative insulin resistance after donor hepatectomy in terms of donor outcomes. Investigator will analyze the data and elucidate the value of post operative insulin resistance in reducing the occurrence of complications, length of …

Accepts healthy volunteers
  • 0 views
  • 07 Apr, 2022
  • 1 location
Phase I Study of RiMO-301 With Radiation in Advanced Tumors

This is a prospective, open-label, single arm, non-randomized study of RiMO-301 with radiation in patients with advanced tumors. A single escalation dose of RiMO-301 is intratumorally injected in a 3 + 3 study design to identify the recommended dose and dosing volumes. Condition or Disease: Patient with advanced tumor which …

  • 0 views
  • 21 Mar, 2022
  • 2 locations
Optimizing the Previs Device for Prediction of Postoperative Ileus

The research proposed in this study will develop a noninvasive prototype device that will capture intestinal sounds, process signals, and display predictive information in real-time at the point-of-care using algorithms already developed at this institution.

colorectal surgery
postoperative ileus
vomiting
nausea
flatus
  • 25 views
  • 03 Mar, 2022
  • 1 location
Study of CPI-100 in Patients With Advanced Tumors

This is a prospective, open-label, 2-arm, non-randomized study of CPI-100 in patients with advanced tumors. CPI-100 is administered via intravenous infusion in a 3 + 3 study design to identify the maximum tolerated dose (MTD).

  • 5 views
  • 24 Mar, 2022
  • 3 locations
Role of Preoperative Transdermal Buprenorphine Patch in Reducing Postoperative Opioids Consumption in Patients Undergoing Total Knee Arthroplasties - A Randomised Controlled Trial.

This study will help us in understanding the role of transdermal buprenorphine patch in reducing consumption of opioids in patients undergoing total knee replacement. The objective of our study is to investigate the role of preoperative TDB patch in reducing postoperative opioids consumption in patients undergoing total knee arthroplasties. Patients …

  • 0 views
  • 22 Apr, 2022
  • 1 location
Vaped Marijuana to Attenuate Naloxone-Precipitated Withdrawal

The goal of the proposed, proof-of-concept study is to test the combined effects of vaporized marijuana [Delta-9-tetrahydracannabinol (THC)] with NLX as a proof of concept towards the possible development of a combined overdose reversal agent with improved tolerability.

  • 0 views
  • 08 Dec, 2021
  • 1 location