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Found 1436 clinical trials
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Parkinson's Research With Inclusion, Diversity and Equity (PRIDE)

The purpose of this study is to identify the health and healthcare needs of LGBTQIA+ and non LGBTQIA+ communities living with Parkinson's disease.

Accepts healthy volunteers
  • 24 Oct, 2022
  • 1 location
C-FLASH (Cigarillo Flavor and Abuse Liability, Attention, and Substitution in youtH)

The purpose of this research is to understand how flavor affects young adult's perceptions of little cigar or cigarillo use.

  • 09 Jul, 2022
  • 1 location
An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia (PEDZ-K)

approximately 46 sites in locations including but not limited to Europe and North America for this study. Treatment will include 3 phases: the CP, MP, and LTMP. Enrolment will start in 2 cohorts, ages 6 to &lt

  • 11 Oct, 2022
  • 18 locations
A Phase 3, Open-Label, Randomized Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer After Osimertinib Failure (MARIPOSA-2)

pemetrexed (CP), respectively, in participants with locally advanced or metastatic epidermal growth factor receptor (EGFR) Exon 19del or Exon 21 L858R substitution non-small cell lung cancer (NSCLC) after

epidermal growth factor receptor
measurable disease
brain metastases
  • 23 Oct, 2022
  • 217 locations
Evaluating Effects of Integrating ECD Activities Into Bangladesh Government's Urban Lactating Mothers Allowance Program for the Poor on Children's Cognition and Behavior in Rangpur City Corporation, Bangladesh

patchy and fragmented. The poor urban people, especially mothers have little access to government health facilities. The health care platform is not well designed in primary health care delivery for

Accepts healthy volunteers
  • 24 Mar, 2022
  • 1 location
Implementation of Shared Decision Making in Rheumatoid Arthritis: A Stepped Wedge, Cluster-randomized Trial (RAiSeD)

disparities, however there is little evidence to inform effective ways to implement this practice in the care of Veterans with RA. The purpose of this project is to evaluate the effectiveness of a multi

  • 21 Oct, 2022
  • 3 locations
A Multi-center, Open-label Study to Determine the Dose and Safety of Oral Asciminib in Pediatric Patients With Philadelphia Chromosome Positive Chronic Myeloid Leukemia in Chronic Phase (Ph+ CML-CP), Previously Treated With One or More Tyrosine Kinase Inhibitors

The aim of this study is to support development of asciminib in the pediatric population (1 to <18 years) previously treated with one or more TKIs. Full extrapolation of the efficacy of asciminib from adult to pediatric patients will be conducted. Full extrapolation is based on the concept that CML …

  • 20 Oct, 2022
  • 24 locations
The Role of Emotional and Orientation Support in Prevention of Postoperative Delirium Among Elderly Surgical Patients

Postoperative delirium is common and associated with significant adverse outcomes. Its etiology is unknown, and little is known about associated risk factors. The investigatorea aim to test

  • 28 Jun, 2022
  • 1 location
Emergency Department-Initiated Buprenorphine Validation Network Trial

Withdrawal Scale (COWS) scores < 8 in a case series to potentially expand the eligibility of patients in the larger RCT to those presenting with little to no opioid withdrawal symptoms. Finally, the

  • 22 Oct, 2022
  • 17 locations
HElping Alleviate the Longer-term Consequences of COVID-19 (HEAL-COVID)

little work evaluating treatments in the convalescent phase of COVID-19. HEAL-COVID aims to evaluate the impact of treatments on longer-term morbidity, mortality, re-hospitalisation, symptom burden and

  • 02 Aug, 2021
  • 1 location