Found 37 clinical trials
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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1000s of participants
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An interventional trial
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For all genders
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Neurology
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Currently Recruiting
Early Rivaroxaban for Acute Ischemic Stroke or TIA Patients With Atrial Fibrillation
European guidelines recommend that the timing of the initiation of non-vitamin K antagonist oral anticoagulants (NOACs) for AF patients with cerebral infarction or TIA is association with stroke severity
- 13 views
- 11 Feb, 2021
- 1 location
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Multi-country trial
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Phase 3 trial
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Accepting pediatric ages
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Pulmonary/Respiratory Diseases
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Currently Recruiting
Hokusai Study in Pediatric Patients With Confirmed Venous Thromboembolism (VTE)
This is an event driven Phase 3, prospective, randomized, open-label, blinded endpoint evaluation (PROBE) parallel group study in subjects with confirmed VTE. This study is designed to evaluate the pharmacokinetics (PK) and pharmacodynamics (PD) of edoxaban and to compare the efficacy and safety of edoxaban against standard of care in …
- 0 views
- 28 Jan, 2021
- 170 locations
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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1000s of participants
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An interventional trial
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For all genders
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Pediatrics/Neonatology
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Currently Recruiting
Left Atrial Appendage CLOSURE in Patients With Atrial Fibrillation Compared to Medical Therapy
The study goal is to determine the clinical benefit of percutaneous catheter-based left atrial appendage (LAA) closure in patients with non-valvular atrial fibrillation (NVAF) at high risk of stroke (CHA2DS2-VASc Score 2) as well as high risk of bleeding as compared to best medical care (including a [non-vitamin K] oral …
- 13 views
- 23 Jan, 2021
- 32 locations
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Pediatrics/Neonatology
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Currently Recruiting
Comparison of LAA-Closure vs Oral Anticoagulation in Patients With NVAF and Status Post Intracranial Bleeding.
Atrial fibrillation is the most common cardiac arrhythmia. In atrial fibrillation, there is a risk that clots can form in the heart, especially in the left atrium. If these clots come loose, there is a risk of stroke. To prevent strokes, patients with atrial fibrillation and status post ICB can …
- 0 views
- 24 Jan, 2021
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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1000s of participants
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An interventional trial
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For all genders
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Currently Recruiting
API-CAT STUDY for APIxaban Cancer Associated Thrombosis
The main objective is to determine whether a low-dose regimen of apixaban (2.5 mg bid) is non inferior to a full-dose regimen of apixaban (5 mg bid) for the prevention of recurrent venous thromboembolism (VTE) in patients with active cancer who have completed at least 6 months of anticoagulant therapy …
- 8 views
- 29 Jan, 2021
- 70 locations
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Multi-country trial
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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1000s of participants
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An interventional trial
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For all genders
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Neurology
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Currently Recruiting
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop new-onset post-operative atrial fibrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery. All patients with a qualifying …
- 112 views
- 24 Feb, 2021
- 76 locations
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Treatment of Intracerebral Hemorrhage in Patients on Non-vitamin K Antagonist
Novel, non-vitamin K antagonist oral anticoagulants (NOAC) target selected players in the coagulation cascade as the direct thrombin inhibitor dabigatran and the factor Xa-inhibitors apixaban
- 19 views
- 25 Jan, 2021
- 1 location
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Phase 4 trial
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Accepting adults
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100s of participants
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An interventional trial
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For females only
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Family Medicine
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Currently Recruiting
Use of Warfarin After the First Trimester in Pregnant Women With APS
Evaluation of shifting to oral vitamin K antagonist after the first trimester instead of using low molecular weight heparin (LMWH) throughout pregnancy in pregnant women with antiphospholipid
- 135 views
- 24 Jan, 2021
- 2 locations
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Pediatrics/Neonatology
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Currently Recruiting
Compare Apixaban and Vitamin-K Antagonists in Patients With Atrial Fibrillation (AF) and End-Stage Kidney Disease (ESKD)
The Study is an open-labeled, randomized controlled trial, phase IIIb. Its objective is to assess the safety of the factor Xa inhibitor apixaban versus the vitamin-K antagonist (VKA
- 6 views
- 25 Jan, 2021
- 3 locations
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Pediatrics/Neonatology
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Currently Recruiting
Avoiding Anticoagulation After IntraCerebral Haemorrhage
). However, these RCTs excluded patients with prior intracerebral haemorrhage (ICH). Therefore, guidelines are unable to recommend whether oral anticoagulant drugs, in particular non-vitamin K antagonist
- 0 views
- 25 Jan, 2021
- 2 locations