Found 78 clinical trials
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Phase 2 trial
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Accepting adults
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10s of participants
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An interventional trial
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For females only
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Cardiology/Vascular Diseases
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Currently Recruiting
RAMBLE - Rivaroxaban vs. Apixaban for Heavy Menstrual Bleeding
A large proportion of women with menstruating potential with newly diagnosed VTE or atrial fibrillation, treated with apixaban will have less menstrual blood loss than patients randomized to rivaroxaban.
- 210 views
- 23 Jan, 2021
- 2 locations
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Cardiology/Vascular Diseases
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Currently Recruiting
Treatment of Post-STEMI Left Ventricular Thrombus With Optimized Anticoagulant
Left ventricular thrombus is a common complication subsequent to ST-segment elevation myocardial infarction (STEMI) that related to increased embolic events. This study aims to assess the efficacy and safety outcomes of Rivaroxaban on the treatment of post-STEMI left ventricular thrombus.
- 0 views
- 24 Jan, 2021
- 1 location
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Cardiology/Vascular Diseases
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Currently Recruiting
Aspirin Plus Rivaroxaban Versus Rivaroxaban Alone for the Prevention of Venous Stent Thrombosis in Patients With PTS
To show if a combination therapy of rivaroxaban plus Aspirin is more efficient (superiority testing) as rivaroxaban alone in the prevention of early venous stent thrombosis in patients suffering from post-thrombotic syndrome in the first 6 months following endovascular therapy To demonstrate tolerability of combination therapy of Aspirin plus rivaroxaban …
- 51 views
- 24 Jan, 2021
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Cardiology/Vascular Diseases
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Currently Recruiting
A Nurse-coordinated Integrated Care Model for Patients With Atrial Fibrillation
This study aims to evaluate the effects of a nurse-coordinated, empowerment-based integrated care model on self-care behaviors and psychosocial outcomes in patients with atrial fibrillation (AF), and to explore how this intervention affects the self-care behaviors and quality of life from the patients' perspective. Stroke prevention by oral anticoagulants (OAC) …
- 1 views
- 27 Jan, 2021
- 1 location
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Phase 1 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Hepatology (Liver, Pancreatic, Gall Bladder)
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Currently Recruiting
Biliary Tissue Sampling Using a Cytology Brush or the GIUM Catheter
Introduction In patients with a biliary obstruction, tissue is acquired immediately before drainage during endoscopic retrograde cholangio-pancreatography (ERCP). This is performed by passing a brush inside the bile duct stricture. However, brush cytology has a modest sensitivity (30-57%) for the diagnosis of cancer. A device, called the "G.I.U.M." catheter, allows …
- 43 views
- 07 Nov, 2020
- 3 locations
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Phase 2 trial
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Accepting pediatric ages
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
The Preterm Infants' Paracetamol Study
Present randomized, controlled, double-blind trial investigates the efficacy and safety of early (<24 h) intravenous paracetamol therapy for pain medication in very small premature infants. This phase 2 drug study focuses on the efficacy and safety of short-term use. The pharmacokinetics and pharmacodynamics of paracetamol, as well as the long-term …
- 0 views
- 26 Jan, 2021
- 1 location
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Accepting Seniors
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Accepting adults
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1000s of participants
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An observational study
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For all genders
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Hematology
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Currently Recruiting
An Observational Cohort Study to Investigate the Risk of Thromboembolic Events in Patients Receiving Kcentra or Plasma to Reverse Vitamin K Antagonist (VKA) Therapy in the Setting of Acute Major Bleeding
major bleeding in which patients are treated for Vitamin K antagonist reversal, the risk of thromboembolic events (TEE) in patients treated with Kcentra and in patients treated with plasma will be
- 13 views
- 24 Jan, 2021
- 1 location
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Accepting Seniors
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Accepting adults
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An observational study
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For all genders
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Currently Recruiting
Stroke Prevention in Atrial Fibrillation Patients Between 2004 and 2020
Prevention of thromboembolic complications is an important part in the management of patients with atrial fibrillation (AF). European and American guidelines recommend the use of non-vitamin K
- 0 views
- 29 Jan, 2021
- 2 locations
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Accepting Seniors
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Accepting adults
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100s of participants
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An observational study
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For all genders
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Currently Recruiting
Risk of Recurrent Venous Thromboembolism After Provoked Venous Thromboembolism
further by prolonged anticoagulation is outweighed by the bleeding risk. However, the newer direct oral anticoagulants are potentially associated with a lower bleeding risk than vitamin K antagonists
- 0 views
- 23 Jan, 2021
- 1 location
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Accepting Seniors
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Accepting adults
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1000s of participants
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An observational study
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For all genders
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Cardiology/Vascular Diseases
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Currently Recruiting
Benefit/Risk in Real Life of New Oral Anticoagulants and Vitamin K Antagonists in Patients Aged 80 Years and Over
(DOA) and with anti vitamin K (VKA) in older adults ( 80 years) suffering from non valvular atrial fibrillation and living in community or nursing home settings. An observational multicenter
- 3 views
- 23 Jan, 2021
- 2 locations