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Found 78 clinical trials
Left Atrial Appendage Occlusion for AF Patients Unable to Use Oral Anticoagulation Therapy

Up to 5% of Atrial Fibrillation (AF) patients may have or develop contraindications to use oral anticoagulation (OAC). Randomized controlled trial (RCT) data suggest that Left Atrial Appendage Occlusion (LAAO) may provide a non-inferior alternative for cardioembolic stroke protection in patients tolerant to OAC. However, RCT data for LAAO is …

  • 0 views
  • 03 Mar, 2021
  • 1 location
PREvention of STroke in Intracerebral haemorrhaGE Survivors With Atrial Fibrillation

Atrial fibrillation (AF) is the most common form of irregular heart rhythm. In people with AF, blood clots often form in the heart, which can travel to the brain. Blockage of brain arteries by these clots is a major cause of stroke. This type of stroke is called an ischaemic …

warfarin
apixaban oral tablet
rivaroxaban
edoxaban
anticoagulants
  • 13 views
  • 25 Feb, 2021
  • 28 locations
Vitamin K to Slow Progression of Cardiovascular Disease Risk in Hemodialysis Patients

been growing interest in the vitamin K-dependent matrix Gla protein (MGP) and its role in inhibiting vascular calcification. Animal studies have revealed that the vitamin K-dependent protein MGP may

cardiovascular disease
nephropathy
renal failure
chronic disease
vitamins
  • 73 views
  • 23 Jan, 2021
  • 1 location
Treatment of Intracerebral Hemorrhage in Patients on Non-vitamin K Antagonist

Novel, non-vitamin K antagonist oral anticoagulants (NOAC) target selected players in the coagulation cascade as the direct thrombin inhibitor dabigatran and the factor Xa-inhibitors apixaban

hematoma
noac
rivaroxaban
apixaban
anticoagulants
  • 19 views
  • 25 Jan, 2021
  • 1 location
The Clinical Effect of Vitamin K Administration in Type 2 Diabetic Patients

The aim of this study is to examine the possible clinical effects associated with vitamin K supplementation on the glycemic control, insulin sensitivity and lipid profile of type II diabetic

insulin sensitivity
fasting blood glucose
fasting
  • 2 views
  • 23 Jan, 2021
  • 1 location
Rivaroxaban and Vitamin K Antagonists for the Anticoagulation for the Implantation of Vena Cava Filters

The purpose of this study is to evaluate the efficacy and safety of new oral anticoagulants and vitamin K antagonists for the anticoagulation for the implantation of vena cava filters in

vitamin k
warfarin
deep vein thrombosis
rivaroxaban
vitamin k antagonist
  • 0 views
  • 25 Jan, 2021
  • 7 locations
Compare Apixaban and Vitamin-K Antagonists in Patients With Atrial Fibrillation (AF) and End-Stage Kidney Disease (ESKD)

The Study is an open-labeled, randomized controlled trial, phase IIIb. Its objective is to assess the safety of the factor Xa inhibitor apixaban versus the vitamin-K antagonist (VKA

fibrillation
dialysis
nephropathy
atrial flutter
embolism
  • 6 views
  • 25 Jan, 2021
  • 3 locations
Use of Warfarin After the First Trimester in Pregnant Women With APS

Evaluation of shifting to oral vitamin K antagonist after the first trimester instead of using low molecular weight heparin (LMWH) throughout pregnancy in pregnant women with antiphospholipid

vitamin
warfarin
antiphospholipid syndrome
early pregnancy
vitamin k antagonist
  • 135 views
  • 24 Jan, 2021
  • 2 locations
The Association of Warfarin Dosage and Plasma Enantiomer Concentration With the Gene Polymorphisms of CYP and VKOR

metabolism of warfarin. The vitamin K epoxide redutase (VKOR) is a liver enzyme associated with the reuse of the oxidative hydroquinone form of vitamin K. The VKOR enzyme is the target of warfarin

  • 9 views
  • 07 Nov, 2020
Avoiding Anticoagulation After IntraCerebral Haemorrhage

). However, these RCTs excluded patients with prior intracerebral haemorrhage (ICH). Therefore, guidelines are unable to recommend whether oral anticoagulant drugs, in particular non-vitamin K antagonist

left atrial appendage closure
fibrillation
vitamin k
electrocardiogram
vitamin k antagonist
  • 0 views
  • 25 Jan, 2021
  • 2 locations