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Found 3 clinical trials
A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma

Historically, medulloblastoma treatment has been determined by the amount of leftover disease present after surgery, also known as clinical risk (standard vs. high risk). Recent studies have shown that medulloblastoma is made up of distinct molecular subgroups which respond differently to treatment. This suggests that clinical risk alone is not …

primitive neuroectodermal tumor
residual tumor
medulloblastoma
tumor cells
corticosteroids
  • 144 views
  • 25 May, 2022
  • 1 location
Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

This phase II trial studies how well vismodegib, focal adhesion kinase (FAK) inhibitor GSK2256098, and capivasertib work in treating patients with meningioma that is growing, spreading, or

tumor cells
vismodegib
gsk2256098
  • 4 views
  • 17 Jun, 2022
  • 517 locations
Safety and Efficacy of ASN-002 Combined With a Hedgehog Pathway Inhibitor

The primary objectives are to: Evaluate the safety and tolerability of intralesional ASN-002 when administered in combination with oral vismodegib in patients with Basal Cell

carcinoma
hedgehog pathway inhibitor
asn-002
punch biopsy
platelet count
  • 0 views
  • 25 Mar, 2022
  • 5 locations