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Found 73 clinical trials
Characterization of Acute and Recent HIV-1 Infections in Zurich: a Long-term Observational Study

. After one year of suppressed HIV-plasma viremia (< 50 copies/ml) patients can chose to stop cART. Patients who have not chosen to undergo early-cART, respectively will stop cART after one year will

cobicistat
hiv-1 infection
lamivudine
darunavir
antiretroviral agents
  • 9 views
  • 07 Nov, 2020
  • 1 location
A Study of a Nucleoside Sparing Regimen in HIV-1 Infected Patients With Detectable Viremia

Research ipotesis is to assess the efficacy and safety of a nucleos(t)ide sparing regimen of atazanavir/ritonavir 300 mg /100 mg QD + Dolutegravir 50 mg QD for the management of virological failure in HIV-1 infected patients. The Primary Objective is to explore the 24-week efficacy of a nucleos(t)ide sparing regimen …

  • 0 views
  • 08 Nov, 2020
  • 1 location
Monitored Antiretroviral Pause in Chronic HIV-Infected Subjects With Long-Lasting Suppressed Viremia

Prospective, open-label, single arm, non-randomized, proof-of-concept study. Eligible patients will sign a written informed consent and will be followed-up at screening, baseline (ART interruption) and at 1, 2, 3, 4, 6, 8, 10, 12, 16, 24, 32, 40, 48 weeks thereafter or at ART resumption. The study visits will include: …

  • 5 views
  • 08 Nov, 2020
  • 1 location
Multicenter Randomized Two-arms Study Evaluating the BK Viral Clearance in Kidney Transplant Recipients With BK Viremia.

recent cohorts, BKVN concerns up to 10% of kidney transplant recipients and early signs of BK virus (BKV) infection as development of asymptomatic viruria and viremia are even much more frequent (40% and

  • 18 views
  • 08 Nov, 2020
  • 1 location
Treatment of BK Virus Infection With CTL Cells in Immunocompromised Transplant Patients

with BK virus viremia and BK virus-associated symptoms post-allogeneic hematopoietic stem cell transplantation (HSCT), renal transplantation, and chemotherapy.

  • 0 views
  • 08 Mar, 2020
  • 1 location
Switch From Dual Regimens Based on Dolutegravir Plus a Reverse Transcriptase Inhibitor to E/C/F/TAF in Virologically Suppressed HIV-1 Infected Patients (Be-OnE)

), lowers the exposure to Residual Viremia (and hence the risk of viral rebound), without increasing treatment toxicity.

  • 5 views
  • 08 Nov, 2020
  • 1 location
Immunogenicity and Safety of the Yellow Fever Vaccine in HIV Infected Individuals

of neutralizing antibodies are associated with CD4 lymphocyte counts, CD8 lymphocyte counts, CD4 nadir, HIV viral load and use of antiretroviral therapy. To assess the yellow fever vaccine viremia at

hiv viral load
antiretroviral agents
HIV Vaccine
viremia
antiretroviral therapy
  • 6 views
  • 08 Nov, 2020
  • 1 location
Ezetimibe as a Safe and Efficacious Treatment for Chronic Hepatitis C

for the treatment of chronic HCV. The investigators predict that when administered as monotherapy ezetimibe will reduce HCV viremia perhaps allowing for viral clearance and that when included in

diabetes
liver disease
antiviral drugs
chronic hepatitis
  • 93 views
  • 28 Oct, 2020
  • 1 location
Brief Acceptance-Based Retention Intervention for Newly Diagnosed HIV Patients

The overall aim of this program of research is to test a newly developed intervention, Acceptance-Based Behavior Therapy (ABBT), to improve HIV patients' commitment to medical care. The purpose of the proposed project is to establish the efficacy of ABBT and examine its mechanisms of action. To achieve the specific …

behavior therapy
  • 0 views
  • 27 Sep, 2020
  • 1 location
Conversion to Envarsus Post Kidney Transplant Protects Against BK Infection

The purpose of this study is to assess if the use of Envarsus in place of Tacrolimus-immediate release (IR) in rapid metabolizers post kidney transplant will reduce incidence of BK infection. Efficacy evaluations will include measurement of urine and serum BK values at specified time points and review of any …

  • 2 views
  • 07 May, 2020
  • 1 location