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Found 37 clinical trials
The Safety of Molnupiravir (EIDD-2801) and Its Effect on Viral Shedding of SARS-CoV-2 (END-COVID)

Designed as a multi-center, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of EIDD-2801 on SARS-CoV-2 Virus Shedding in Newly Hospitalized Adults with polymerase chain reaction (PCR)-Confirmed COVID-19.

dyspnea
fever
cough
PCR test
anosmia
  • 40 views
  • 24 Feb, 2021
  • 12 locations
Talimogene Laherparepvec for the Treatment of Peritoneal Surface Malignancies

from gastrointestinal or recurrent, platinum-resistant ovarian tumors. The secondary objectives are to evaluate the pharmacokinetic profile and viral shedding of TVEC by measuring viral load in serum

  • 18 views
  • 17 Feb, 2021
  • 3 locations
Clinical Trial of Novel OPV2 Vaccine

newborns Viral Shedding To assess trate of fecal viral shedding at fixed time points following one and two doses of nOPV2 vaccine candidate 1 in newborns To assess duration of fecal viral

  • 0 views
  • 27 Jan, 2021
  • 1 location
Effects of Surgical Mask Use on Peak Torque Total Work and Interset Fatigability During Isokinetic Strength Testing

are recommended at all levels for source control as a simple barrier to help prevent respiratory droplet transmission. It is important to remember that increased viral shedding occurs during elevated

  • 0 views
  • 31 Jan, 2021
  • 1 location
Steam Inhalations in COVID-19 Patients

inhalation for at least 20 min (4 cycles of 5 min) daily, for 10 days. The objective of the study is to reduce the viral shedding using steam inhalations.

  • 0 views
  • 15 Feb, 2021
  • 1 location
COVID-19 Treatment in South Africa

This exploratory study is a randomized, single center, open label study of four different experimental treatment arms versus standard of care for the treatment of SARS-CoV-2 infection in symptomatic outpatients with mild disease at the time of enrollment.

  • 117 views
  • 29 Jan, 2021
  • 1 location
Detection of SARS-CoV-2 in Semen of COVID-19 Positive Males

The objectives of the study, are to describe detection of SARS-CoV-2 in the semen of COVID-19 positive patients, the duration of positive semen and to investigate the impact on semen quality, thereby providing insights into the early impact on male reproductive function.

nasopharyngeal swab
covid-19
SARS
  • 0 views
  • 26 Jan, 2021
  • 1 location
A Clinical Study of T3011 in Patients With Advanced Cutaneous or Subcutaneous Malignancies

A phase 1, open-label, first-in-human study of T3011 monotherapy to evaluate the safety and tolerability of T3011 in patients with advanced cancers with cutaneous or subcutaneous tumor deposits who have progressed while receiving standard of care therapy or who will not benefit from such therapy.

cancer
cancer treatment
serum pregnancy test
measurable disease
screening procedures
  • 7 views
  • 15 Feb, 2021
  • 8 locations
Safety and Tolerability Study of RSV Prophylactic Drug for Immunocompromised Children

Study D5290C00008 is a Phase 2, open-label, uncontrolled, single-dose study to evaluate the safety and tolerability, PK, occurrence of ADA, and efficacy of nirsevimab in immunocompromised Japanese children who are 24 months of age at the time of dose administration. Approximately 30 subjects will be enrolled. Subjects will be followed …

tacrolimus
corticosteroid therapy
immunodeficiency
HIV Infection
methotrexate
  • 15 views
  • 03 Feb, 2021
  • 4 locations
Treatment With Investigational Convalescent Plasma and Measure Antibody Levels in Patients Hospitalized With COVID-19

This is an open label pilot study designed to provide access to treatment with investigational convalescent plasma and assess the relationship between NAb titers in the investigational convalescent plasma compared to changes in NAb levels in the recipient in hospitalized patients with COVID-19.

respiratory symptom
covid-19
  • 77 views
  • 25 Jan, 2021
  • 1 location