Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 33 clinical trials
Catalysing the Containment of COVID-19

COVID-19 due to SARS-CoV-2 infection is a rapidly escalating global pandemic for which there is no proven effective treatment. COVID-19 is multi-dimensional disease caused by viral cytopathic effects and host-mediated immunopathology. Therapeutic approaches should logically be based on interventions that have direct anti-viral effects and favourably modulate the host immune …

ebola virus disease
nitazoxanide
organ failure
antihypertensive drugs
interferon
  • 42 views
  • 25 Jan, 2021
  • 1 location
Assessement of Viral Shedding Duration After a Respiratory Tract Infection in Oncology and Hematology Patients

The purpose of this study is to assess the duration of the viral shedding in hematology and oncology patients after a respiratory tract viral infection. This duration has not been much studied

  • 1 views
  • 24 Jan, 2021
  • 1 location
Oral Camostat Compared With Standard Supportive Care in Mild-Moderate COVID-19 Patients

This study will evaluate the efficacy of oral Foipan (camostat mesilate) compared with the current standard of care in reducing the duration of viral shedding of SARS-CoV-2 virus in patients

  • 0 views
  • 26 Jan, 2021
  • 1 location
Effects of Surgical Mask Use on Peak Torque Total Work and Interset Fatigability During Isokinetic Strength Testing

are recommended at all levels for source control as a simple barrier to help prevent respiratory droplet transmission. It is important to remember that increased viral shedding occurs during elevated

  • 0 views
  • 27 Jan, 2021
  • 1 location
NNITS-Nitazoxanide for Norovirus in Transplant Patients Study

prolonged therapy with nitazoxanide, lack of interactions with common post-transplant medications, putative antiviral activity and prolonged duration of viral shedding we are assessing 56 doses of therapy

  • 82 views
  • 27 Jan, 2021
  • 13 locations
Convalescent Plasma to Limit SARS-CoV-2 Associated Complications

oropharyngeal viral shedding.

coronavirus infection
anosmia
fever
oropharyngeal
SARS
  • 0 views
  • 27 Jan, 2021
  • 29 locations
The Containing Coronavirus Disease 19 (COVID-19) Trial

type 1 interferon (IFN) can potentially eliminate the spread of SARS-CoV-2. IFN could reduce the period of viral shedding by ~1 week. Since pre-symptomatic shedding of virus can start up to 5 days

  • 0 views
  • 26 Jan, 2021
  • 1 location
Hydroxychloroquine Efficacy and Safety in Preventing SARS-CoV-2 Infection and COVID-19 Disease Severity During Pregnancy

It still unclear how SARS-CoV-2 affects pregnant women and their offspring, as well as which factors may influence obstetrical disease and outcomes, including the timing of maternal viral exposure by gestational age, the effects of parity, age, host immune responses, coexisting medical and obstetrical conditions and the effects of treatment …

anosmia
myalgia
headache
hydroxychloroquine
fever
  • 251 views
  • 27 Jan, 2021
  • 4 locations
Control of COVID-19 Outbreaks in Long Term Care

To address the need to intervene to prevent the spread of COVID-19 in long-term care homes, we propose a randomized clinical trial of chemoprophylaxis in long-term care homes experiencing COVID-19 outbreaks. LTCH units experiencing an outbreak of COVID-19 will be randomized to chemoprophylaxis with favipiravir or placebo in a 1:1 …

covid-19
favipiravir
post-exposure prophylaxis
  • 0 views
  • 26 Jan, 2021
  • 1 location
Efficacy & Safety of rAd-IFN Administered With Celecoxib & Gemcitabine in Patients With Malignant Pleural Mesothelioma

This study will evaluate intrapleural administration of Adenovirus-Delivered Interferon Alpha-2b (rAd-IFN) in combination with Celecoxib and Gemcitabine in patients with histologically confirmed Malignant Pleural Mesothelioma (MPM) who have failed a minimum of 1 treatment regimen and a maximum of 2 treatment regimens, 1 of which must have been an anti-folate …

anticoagulation therapy
international normalized ratio
neutrophil count
platelet count
treatment regimen
  • 24 views
  • 26 Jan, 2021
  • 53 locations