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A Biomarker-Driven Master Protocol for Previously Treated Squamous Cell Lung Cancer (Screening Step) Lung-MAP Study

A Biomarker-Driven Master Protocol for Previously Treated Squamous Cell Lung Cancer (Screening Step) Lung-MAP Study

lung carcinoma
lung cancer
cancer
  • 28 views
  • 23 Nov, 2020
  • 1 location
Adjuvant Vinorelbine Plus Cisplatin (NP) Versus NP Plus Endostar in Patients With Completely Resected Stage IB-IIIA Non-small Cell Lung Cancer

This study was designed to determine whether adjuvant vinorelbine plus cisplatin and endostar prolongs overall survival compare to vinorelbine plus cisplatin alone among patients with

kidney function test
serum bilirubin level
vinorelbine
carcinoma
adjuvant chemotherapy
  • 4 views
  • 07 Nov, 2020
  • 1 location
A Study to Evaluate Vinorelbine Plus Capecitabine Combined With Trastuzumab for HER2 Positive Patients Following Neoadjuvant Chemotherapy

This study aims to evaluate vinorelbine plus capecitabine combined with trastuzumab versus trastuzumab alone as the adjuvant Treatment of HER2 positive patients following neoadjuvant

immunostimulant
chromogenic in situ hybridization
vinorelbine
trastuzumab
carcinoma
  • 3 views
  • 15 Mar, 2020
  • 1 location
Multicenter Randomized Controlled Trial Adjuvant Chemotherapy vs Observation in pStage Ib Lung Adenocarcinoma

vinorelbine plus cisplatin will be admitted for 4 cycles. Also the three days before and the after the estimated day are permitted as allowance. Intravenous administration of vinorelbine (25mg

  • 10 views
  • 08 Nov, 2020
  • 1 location
Study of IMMU-132 in HR+/HER2- MBC (TROPICS-02)

This is an open-label, randomized, multicenter Phase 3 study to compare the efficacy and safety of Sacituzumab Govitecan versus TPC in subjects with metastatic or locally recurrent inoperable HR+/HER2- MBC, after failure of at least 2, and no more than 4, prior chemotherapy regimens for metastatic disease.

capecitabine
vinorelbine
eribulin
cancer chemotherapy
HER2
  • 66 views
  • 05 Oct, 2020
  • 105 locations
Combination Chemotherapy in Treating Young Patients With Nonmetastatic Rhabdomyosarcoma

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. It is not yet known which combination chemotherapy regimen is more …

tumor cells
vinorelbine
ifosfamide
combination chemotherapy
conventional surgery
  • 103 views
  • 07 Nov, 2020
  • 9 locations
Vinorelbine in Advanced BRAF-like Colon Cancer

microtubule outgrowth from the kinetochores, thereby inducing spindle perturbations, providing an explanation for the observed mitotic defects. Vinorelbine mimics RANPB2 silencing in BRAF-like and BRAFV600E

platelet count
KRAS
liver metastasis
metastasis
BRAF
  • 5 views
  • 08 Nov, 2020
  • 1 location
Vinorelbine Cisplatin Disulfiram and Copper in CTC_EMT Positive Refractory Metastatic Breast Cancer.

This is a proof-of-concept study to define efficacy of vinorelbine, cisplatin, disulfiram and copper in CTC_EMT positive refractory metastatic hormone receptor positive, HER2 negative breast

breast cancer
bone metastases
neutrophil count
liver metastasis
endocrine therapy
  • 0 views
  • 16 Feb, 2020
  • 1 location
Safety and Efficacy of Toripalimab in HER2- Metastatic Breast Cancer Patients Treated With Metronomic Vinorelbine

The investigators hypothesize that the administration of Toripalimab (anti-PD-1 antibody, JS001) combined to metronomic Vinorelbine may be an interesting therapeutic option for female patients

breast cancer
neutrophil count
vinorelbine
liver metastasis
metastasis
  • 0 views
  • 07 Sep, 2020
  • 2 locations
Mocetinostat With Vinorelbine in Children Adolescents & Young Adults With Refractory and/or Recurrent Rhabdomyosarcoma

This phase I trial studies the side effects and best dose of mocetinostat when given together with vinorelbine to see how well it works in treating children, adolescents, and young adults with

neutrophil count
vinorelbine
metastasis
cancer
measurable disease
  • 0 views
  • 30 Jul, 2020
  • 1 location