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Found 151 clinical trials
Venetoclax and Vincristine Liposomal in Treating Patients With Relapsed or Refractory T-cell or B-cell Acute Lymphoblastic Leukemia

This phase Ib/II clinical trial studies the side effects and best dose of venetoclax and how well it works when given together with vincristine liposomal in treating patients with T-cell or B

vincristine
mercaptopurine
steroid therapy
arrhythmia
flow cytometry
  • 0 views
  • 07 Mar, 2021
  • 3 locations
EphB4-HSA Fusion Protein and Cytarabine /or Liposomal Vincristine in Patients With Recurrent or Refractory Acute Leukemia

This phase I trial studies the side effects and best dose of recombinant EphB4-HSA fusion protein when given together with cytarabine or vincristine liposomal in treating participants with acute

myeloid leukemia
myeloproliferative disorder
hysterectomy
acute leukemia
blast cells
  • 31 views
  • 22 Jan, 2021
  • 1 location
A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma

This phase III trial studies if selumetinib works just as well as the standard treatment with carboplatin/vincristine (CV) for subjects with NF1-associated low grade glioma (LGG), and to see if

metastatic disease
seizure
vincristine
absolute neutrophil count
ejection fraction
  • 214 views
  • 08 Mar, 2021
  • 42 locations
Ciclophosphamide Vincristine Myocet and Prednisone With Rituximab in 1st-Line Treatment for Patients With No-Hodgkin B Lymphoma and Cardiovascular (CV) Risk

The purpose of this study is to evaluate the efficacy (and safety) of the following treatment squeme:Ciclophosphamide, Vincristine, lyposomal Doxorrubicine (Myocet) and Prednisone

  • 2 views
  • 07 Nov, 2020
  • 5 locations
Ibrutinib Rituximab Etoposide Prednisone Vincristine Sulfate Cyclophosphamide and Doxorubicin Hydrochloride in Treating Patients With HIV-Positive Stage II-IV Diffuse Large B-Cell Lymphomas

This phase I trial studies the side effect and best dose of ibrutinib in combination with rituximab, etoposide, prednisone, vincristine sulfate, cyclophosphamide, and doxorubicin hydrochloride

  • 50 views
  • 25 Feb, 2021
  • 18 locations
Vincristine Sulfate Liposome Injection (Marqibo ) in Combination With UK ALL R3 Induction Chemotherapy for Children Adolescents and Young Adults With Relapsed ALL

This is a pilot study utilizing Marqibo (vincristine sulfate liposome injection) combined with dexamethasone, mitoxantrone and asparaginase (UK ALL R3) for relapsed acute lymphoblastic leukemia

vincristine
dexamethasone
rituximab
ejection fraction
minimal residual disease
  • 0 views
  • 24 Jan, 2021
  • 33 locations
Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS Malignancies

Investigators are testing new experimental drug combinations such as the combination of vorinostat, vincristine, irinotecan, and temozolomide in the hopes of finding a drug that may be effective

bone marrow procedure
pegfilgrastim
chemotherapeutic agents
nitrosoureas
solid tumour
  • 3 views
  • 24 Jan, 2021
  • 1 location
PO Ixazomib in Combination With Chemotherapy for Childhood Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma

This is a phase 1/2 study of a drug called Ixazomib in combination with cytotoxic chemotherapy consisting of Vincristine, Dexamethasone, Asparaginase, and Doxorubicin (VXLD).

vincristine
doxorubicin
dexamethasone
ejection fraction
total body irradiation
  • 3 views
  • 25 Jan, 2021
  • 15 locations
A Phase II Study of Venetoclax in Combination With Dose-adjusted EPOCH-R or R-CHOP for Patients With Richter's Syndrome

drugs involved in this study are: Venetoclax R-EPOCH: Rituximab Etoposide Prednisone Vincristine Sulfate (Oncovin)

  • 16 views
  • 29 Jan, 2021
  • 4 locations
Pembrolizumab in Combination With Chemotherapy for Patients With Untreated B Cell Lymphoma

regimen (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone) therapy.

  • 0 views
  • 27 Jan, 2021
  • 1 location