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Found 136 clinical trials
A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma

This phase III trial studies if selumetinib works just as well as the standard treatment with carboplatin/vincristine (CV) for subjects with NF1-associated low grade glioma (LGG), and to see if

cancer
tumor growth
gilbert disease
selumetinib
giant cell astrocytoma
  • 274 views
  • 12 May, 2022
  • 55 locations
Ibrutinib, Rituximab, Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin Hydrochloride in Treating Patients With HIV-Positive Stage II-IV Diffuse Large B-Cell Lymphomas

This phase I trial studies the side effect and best dose of ibrutinib in combination with rituximab, etoposide, prednisone, vincristine sulfate, cyclophosphamide, and doxorubicin hydrochloride

  • 130 views
  • 19 Apr, 2022
  • 15 locations
Vincristine Sulfate Liposome Injection (Marqibo®) in Combination With UK ALL R3 Induction Chemotherapy for Children, Adolescents, and Young Adults With Relapsed ALL

This is a pilot study utilizing Marqibo (vincristine sulfate liposome injection) combined with dexamethasone, mitoxantrone and asparaginase (UK ALL R3) for relapsed acute lymphoblastic leukemia

ara-c
lymphoma
philadelphia chromosome
hydroxyurea
mitoxantrone
  • 0 views
  • 27 Jan, 2022
  • 16 locations
Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS Malignancies (NYMC195)

Investigators are testing new experimental drug combinations such as the combination of vorinostat, vincristine, irinotecan, and temozolomide in the hopes of finding a drug that may be effective

colony stimulating factor
biological factors
bone marrow procedure
biologic agent
temozolomide
  • 3 views
  • 01 Mar, 2022
  • 1 location
A Study of N9 Chemotherapy in Children With Neuroblastoma

different times - Cyclophosphamide, topotecan, and vincristine (CTV), Ifosfamide, carboplatin, and etoposide (ICE), Cyclophosphamide, doxorubicin, and vincristine (CDV).

carboplatin
topotecan
cyclophosphamide
shortening fraction
vincristine
  • 0 views
  • 18 Aug, 2021
  • 1 location
PO Ixazomib in Combination With Chemotherapy for Childhood Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma

This is a phase 1/2 study of a drug called Ixazomib in combination with cytotoxic chemotherapy consisting of Vincristine, Dexamethasone, Asparaginase, and Doxorubicin (VXLD).

mercaptopurine
lymphoma
hydroxyurea
anthracyclines
lymphoblastic lymphoma
  • 3 views
  • 08 Feb, 2022
  • 15 locations
A Phase II Study of Venetoclax in Combination With Dose-adjusted EPOCH-R or R-CHOP for Patients With Richter's Syndrome

drugs involved in this study are: Venetoclax R-EPOCH: Rituximab Etoposide Prednisone Vincristine Sulfate (Oncovin)

  • 16 views
  • 28 Jan, 2022
  • 2 locations
Testing the Addition of Duvelisib or CC-486 to the Usual Treatment for Peripheral T-Cell Lymphoma

This phase II trial studies the effect of duvelisib or CC-486 and usual chemotherapy consisting of cyclophosphamide, doxorubicin, vincristine, etoposide, and prednisone in treating patients with

measurable disease
cancer
peripheral t-cell lymphoma
cyclophosphamide
etoposide
  • 0 views
  • 28 Apr, 2022
  • 10 locations
Pembrolizumab in Combination With Chemotherapy for Patients With Untreated B Cell Lymphoma

regimen (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone) therapy.

  • 0 views
  • 27 Jan, 2021
  • 1 location
A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma

This feasibility trial studies how well daratumumab in combination with dose-adjusted etoposide, prednisone, vincristine sulfate, cyclophosphamide, and doxorubicin hydrochloride (DA-EPOCH) works

  • 14 views
  • 25 Feb, 2022
  • 5 locations