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Found 150 clinical trials
Tafasitamab + Lenalidomide + R-CHOP Versus R-CHOP in Newly Diagnosed High-intermediate and High Risk DLBCL Patients

lenalidomide in addition to R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) versus R-CHOP in previously untreated, high-intermediate and high-risk patients with newly-diagnosed

  • 0 views
  • 03 Jun, 2021
  • 268 locations
Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

This randomized phase III trial studies how well combination chemotherapy (vincristine sulfate, dactinomycin, cyclophosphamide alternated with vincristine sulfate and irinotecan hydrochloride or

neutrophil count
vincristine
platelet count
cancer
vinorelbine
  • 292 views
  • 13 Jun, 2021
  • 291 locations
Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia

. The purpose of Phase 2 of this study is to compare the rate of complete response (CR) of carfilzomib in combination with vincristine, dexamethasone, PEG asparaginase, daunorubicin (VXLD

  • 125 views
  • 16 May, 2021
  • 79 locations
Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery

or hepatocellular carcinoma. Drugs used in chemotherapy, such as cisplatin, doxorubicin, fluorouracil, vincristine sulfate, carboplatin, etoposide, irinotecan, sorafenib, gemcitabine and oxaliplatin

abdominal compartment syndrome
vincristine
oxaliplatin
cancer therapy
cancer
  • 178 views
  • 13 Jun, 2021
  • 137 locations
A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

tumors (FHWT) that have come back (relapsed). Drugs used in chemotherapy regimens such as UH-3 (vincristine, doxorubicin, cyclophosphamide, carboplatin, etoposide, and irinotecan) and ICE/Cyclo/Topo

  • 0 views
  • 31 May, 2021
  • 53 locations
A Randomized Multicenter Phase III Trial Comparing Treatment With R-mini-CHOP With R-mini-CHP + Polatuzumab Vedotin in Patients With Diffuse Large Cell B Cell Lymphoma

for this population, R-miniCHOP, or an experimental regimen, R-pola-miniCHP, where vincristine is substituted by an immunoconjugate, polatuzumab vedotin. The duration of the screening period is up to

vincristine
high grade b-cell lymphoma
b-cell lymphoma
follicular lymphoma
indolent lymphoma
  • 0 views
  • 27 Jan, 2021
  • 47 locations
Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma

radiation from x-rays to kill cancer cells and shrink tumors. Drugs used in chemotherapy, such as cisplatin, vincristine sulfate, cyclophosphamide and lomustine, work in different ways to stop the growth of

platelet count
cyclophosphamide
cancer
x-rays
tumor cells
  • 119 views
  • 03 Jun, 2021
  • 135 locations
A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

. Drugs used in chemotherapy, such as vincristine, dexamethasone, prednisone, prednisolone, pegaspargase, methotrexate, cytarabine, mercaptopurine, doxorubicin, cyclophosphamide, and thioguanine, work in

pegaspargase
lymphoma
cyclophosphamide
cancer
mercaptopurine oral suspension
  • 84 views
  • 13 Jun, 2021
  • 119 locations
Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma

incidence and/or severity of acute vincristine-induced peripheral neuropathy can be reduced by decreasing the dosage of vincristine in patients with the high-risk CEP72 TT genotype or by shortening the

pegaspargase
vorinostat
lymphoma
cyclophosphamide
consolidation therapy
  • 230 views
  • 29 Jan, 2021
  • 7 locations
High Risk Neuroblastoma Study 1.8 of SIOP-Europe (SIOPEN)

of induction should receive 2 TVD (Topotecan, Vincristine, Doxorubicin) cycles. After Rapid COJEC induction, localized patients will proceed to consolidation. Patients aged 12-18 months at

high-risk neuroblastoma
filgrastim
cyclophosphamide
metastatic neuroblastoma
dinutuximab
  • 288 views
  • 26 Jan, 2021
  • 126 locations