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Found 150 clinical trials
Impact of an Orthotic Intervention in Children With Peripheral Neuropathy

This research study will investigate the effect of two orthotic (brace) devices for the ankle and foot on walking and ankle flexibility in children with cancer not involving the brain or spinal cord.

peripheral neuropathy
spinal cord
cancer
  • 120 views
  • 24 Jan, 2021
  • 2 locations
Clinical Study the Efficacy and Safety of Rh-EPO in the Treatment of Anemia in Lymphoma

The incidence of lymphoma and anemia is high and the clinical harm is great.However, it has not yet attracted enough clinical attention, and domestic rHuEPO (trade name: Ebio).Shenyang Sansheng Pharmaceutical Co., Ltd.) for lymphoma and anemia patients are less clinical studies.Therefore, a prospective, open-label, multicenter clinical study of recombinant human …

chemotherapy regimen
erythropoietin
anemia
lymphoma
  • 0 views
  • 13 Jun, 2021
  • 1 location
Lenalidomide Combined With Modified DA-EPOCH and Rituximab (EPOCH-R2) in Primary Effusion Lymphoma or KSHV-associated Large Cell Lymphoma

Background Primary effusion lymphoma (PEL) is a rare disease with no standard treatment. Researchers want to see if a drug called lenalidomide along with common chemotherapy drugs may be effective in treating PEL. Objective To test a new treatment for PEL. Eligibility People ages 18 and older with PEL. Design …

rituximab
cancer chemotherapy
vincristine
doxorubicin
methotrexate
  • 9 views
  • 13 Jun, 2021
  • 1 location
Early Detection of Neuropathy and Cognitive Impairment Following Treatment for Haematological Malignancies

Chemotherapy-induced peripheral neuropathy (CIPN) is a common, but not well understood complication to treatment with chemotherapy. In this study the investigators will investigate a novel method for early detection of CIPN and compare it to other methods in patients treated for haematological cancers.

lenalidomide
peripheral neuropathy
cancer
bortezomib
vincristine
  • 0 views
  • 25 Jan, 2021
  • 1 location
Diagnostic of Chemotherapy Induced Neuropathy in Children

The purpose of this study is to determine the diagnostic accuracy of a newly developed tool (Electrochemical Skin Conductances (ESC) measurement) easy-to-perform, non-invasive, highly reproductible and not requiring specific training, to identify pediatric chemotherapy-induced-peripheral-neuropathies (CIPN). CIPN are a frequent (20 to 75% depending on the drug), early and potentially severe …

taxane
alkaloids
bortezomib
oxaliplatin
carboplatin
  • 0 views
  • 26 Jan, 2021
  • 1 location
International PPB/DICER1 Registry

Pleuropulmonary blastoma (PPB) is a rare malignant neoplasm of the lung presenting in early childhood. Type I PPB is a purely cystic lesion, Type II is a partially cystic, partially solid tumor, Type III is a completely solid tumor. Treatment of children with PPB is at the discretion of the …

initial diagnosis
sarcoma
cancer
solid tumor
  • 37 views
  • 02 May, 2021
  • 1 location
A Prospective Study of Low-dose Decitabine Combined With COP Regimen in the Treatment of Relapsed and Refractory DLBCL

first-line chemotherapy regimen using Rituximab+Cyclophosphamide+Doxorubicin +Vincristine+BonisoneR-CHOPsignificantly increases the remission rate and disease-free survival of patients with DLBCL, but

  • 0 views
  • 22 Jan, 2021
  • 1 location
Tyrosine Kinase Inhibitors and Low Intensity Chemotherapy in Ph+ ALL

chemotherapy alone. The combination of imatinib, vincristine and dexamethasone is a well tolerated regimen in aged patients and is also associated with a high CR rate of 80% to 90% in patient aged 55 years and

dasatinib
tyrosine
imatinib
vincristine
dexamethasone
  • 8 views
  • 22 Jan, 2021
  • 3 locations
Long Term Implications of Rare Brain Tumours'

Patients diagnosed with oligodendroglioma with a specific molecular profile represent rare tumour groups (about 10% of adult gliomas) with relatively favourable prognosis (median survival between 8 and 12 years). These patients are often treated with surgery, chemotherapy and/or radiotherapy. However, as patients live for a long period of time, they …

  • 0 views
  • 03 Feb, 2021
  • 2 locations
The Potential of Patient-reported Outcome Measures in Detection of Relapse in Diffuse Large B-cell Lymphoma

Annually some 450 patients are diagnosed with Diffuse Large B-cell Lymphoma (DLBCL), in Denmark. The majority of these patients are cured with immunochemotherapy, but up to 30 % will relapse, pointing to the need for targeted surveillance and follow-up strategy. However, this strategy is constantly under debate illustrated by the …

  • 0 views
  • 18 Feb, 2021
  • 1 location