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Found 141 clinical trials
Chemotherapy Induced Peripheral Neuropathy Natural History Study (EPIPHANY) (EPIPHANY)

This is a prospective natural history study of CIPN in approximately 200 participants receiving taxanes (paclitaxel, docetaxel) for breast cancer or vincristine for lymphoma. Participants will

peripheral neuropathy
lymphoma
paclitaxel
nf-l
treatment regimen
  • 19 views
  • 16 Mar, 2022
  • 6 locations
Primary Mediastinal Large B-cell Lymphoma (PMBCL): Multicenter Retrospective Study

The present study consists of a retrospective multicentric collection of all consecutive patients with PMBCL diagnosed over the time period considered (13 years, from 2007 to 2019 inclusive).

  • 0 views
  • 19 Jun, 2022
  • 32 locations
PET Adapted Treatment of Patients With Limited Stage DLBCL and no Risk Factors

Prospective, multicenter, phase IV study, of real-life evidence destined to evaluate the feasibility and efficacy of performing a treatment adapted to PET-CT in patients with stage I and II DLBCL, without poor prognostic factors.

  • 0 views
  • 20 Oct, 2021
  • 2 locations
Early Detection of Neuropathy and Cognitive Impairment Following Treatment for Haematological Malignancies

Chemotherapy-induced peripheral neuropathy (CIPN) is a common, but not well understood complication to treatment with chemotherapy. In this study the investigators will investigate a novel method for early detection of CIPN and compare it to other methods in patients treated for haematological cancers.

cancer
peripheral neuropathy
vincristine
bortezomib
lenalidomide
  • 0 views
  • 25 Jan, 2021
  • 1 location
Diagnostic of Chemotherapy Induced Neuropathy in Children

The purpose of this study is to determine the diagnostic accuracy of a newly developed tool (Electrochemical Skin Conductances (ESC) measurement) easy-to-perform, non-invasive, highly reproductible and not requiring specific training, to identify pediatric chemotherapy-induced-peripheral-neuropathies (CIPN). CIPN are a frequent (20 to 75% depending on the drug), early and potentially severe …

neuralgia
carboplatin
bortezomib
vincristine
oxaliplatin
  • 0 views
  • 15 Dec, 2021
  • 1 location
International PPB/DICER1 Registry

Pleuropulmonary blastoma (PPB) is a rare malignant neoplasm of the lung presenting in early childhood. Type I PPB is a purely cystic lesion, Type II is a partially cystic, partially solid tumor, Type III is a completely solid tumor. Treatment of children with PPB is at the discretion of the …

cancer
initial diagnosis
solid tumor
cancer chemotherapy
Accepts healthy volunteers
  • 37 views
  • 24 Feb, 2022
  • 1 location
Impact of Chemotherapy on Urinary Biomarkers and Non-Invasive Urodynamics in Children

The over-arching aim of this study is to evaluate the effects of two specific anti-cancer chemotherapies, vincristine and doxorubicin, on bladder function and urine composition.

  • 0 views
  • 14 Aug, 2021
  • 1 location
A Prospective Study of Low-dose Decitabine Combined With COP Regimen in the Treatment of Relapsed and Refractory DLBCL

first-line chemotherapy regimen using Rituximab+Cyclophosphamide+Doxorubicin +Vincristine+BonisoneR-CHOPsignificantly increases the remission rate and disease-free survival of patients with DLBCL, but

  • 0 views
  • 22 Jan, 2021
  • 1 location
Tyrosine Kinase Inhibitors and Low Intensity Chemotherapy in Ph+ ALL

chemotherapy alone. The combination of imatinib, vincristine and dexamethasone is a well tolerated regimen in aged patients and is also associated with a high CR rate of 80% to 90% in patient aged 55 years and

philadelphia chromosome
remission
nilotinib
imatinib
dexamethasone
  • 8 views
  • 22 Jan, 2021
  • 3 locations
RWE of Pediatric-like Protocol for AYA Patients With Ph-negative ALL

This is a multicenter, observational real world clinical trial with prospective follow up that will evaluate the treatment outcome of adolescent and young patients with ph-negative acute lymphoblastic leukemia with first-line pediatric-like protocol in Argentina.

  • 0 views
  • 26 Nov, 2021
  • 1 location