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Found 152 clinical trials
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AEWS1031: A Phase III Randomized Trial of Adding Vincristine-Topotecan-Cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-Metastatic Ewing Sarcoma

AEWS1031: A Phase III Randomized Trial of Adding Vincristine-Topotecan-Cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-Metastatic Ewing Sarcoma

  • 376 views
  • 08 Nov, 2020
  • 1 location
featured
N0577 (CODEL) Phase III Intergroup Study of Radiotherapy with Concomitant and Adjuvant Temozolomide versus Radiotherapy with Adjuvant PCV Chemotherapy in Patients with 1p/19q co-deleted Anaplastic Glioma or Low Grade Glioma

PCV (Procarbazine, CCNU, and Vincristine) or radiation with temozolomide during and after radiation, to see which is better.  

brain tumor
oligodendroglioma
vincristine
brain tumors
temozolomide
  • 10 views
  • 24 Jun, 2021
  • 1 location
Combination Chemotherapy in Treating Young Patients With Nonmetastatic Rhabdomyosarcoma

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. It is not yet known which combination chemotherapy regimen is more …

dactinomycin
doxorubicin
combination chemotherapy
etoposide
carboplatin
  • 103 views
  • 07 Nov, 2020
  • 9 locations
Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more …

lymphoid leukemia
asparaginase
cyclophosphamide
combination chemotherapy
cytarabine
  • 1 views
  • 07 Nov, 2020
  • 5 locations
Chemotherapy Before and After Surgery in Treating Children With Wilm's Tumor

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving combination chemotherapy before surgery may shrink the tumor so it can be removed during surgery. Giving more chemotherapy after surgery may kill any remaining tumor cells. It is not …

cyclophosphamide
conventional surgery
nephroblastoma
tumor cells
  • 9 views
  • 07 Nov, 2020
  • 1 location
Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation Radiation Therapy and/or Surgery in Treating Patients With Ewing's Sarcoma

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy and kill more tumor cells. It is …

dactinomycin
doxorubicin
combination chemotherapy
etoposide
conventional surgery
  • 410 views
  • 07 Nov, 2020
  • 4 locations
Biomarker Driven Intensified ChemoImmunotherapy With Early CNS Prophylaxis

This study is testing whether stratification of the patients according to biological risk factors for different treatment groups will improve the outcome of patients with clinically high diffuse large B-cell lymphoma (DLBCL).

transformed lymphoma
follicular lymphoma
t-cell lymphoma
large cell lymphoma
burkitt's lymphoma
  • 32 views
  • 23 Jan, 2021
  • 18 locations
Combination Chemotherapy With or Without Filgrastim Before Surgery High-Dose Chemotherapy and Radiation Therapy Followed by Isotretinoin With or Without Monoclonal Antibody in Treating Patients With Neuroblastoma

RATIONALE: Colony-stimulating factors such as filgrastim may increase the number of immune cells found in bone marrow or peripheral blood and may help a person's immune system recover from the side effects of chemotherapy. Combining chemotherapy with peripheral stem cell transplant may allow the doctor to give higher doses of …

cyclophosphamide
vincristine
etoposide
stem cell transplantation
isotretinoin
  • 46 views
  • 07 Nov, 2020
  • 15 locations
Risk-Adjusted Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. A donor stem cell transplant may replace the patient's immune cells …

prednisone
lymphoid leukemia
asparaginase
cyclophosphamide
combination chemotherapy
  • 0 views
  • 07 Nov, 2020
  • 1 location
Observation Combination Chemotherapy Radiation Therapy and/or Autologous Stem Cell Transplant in Treating Young Patients With Neuroblastoma

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving combination chemotherapy may kill more tumor cells. Radiation therapy uses high-energy x-rays to kill tumor cells. An autologous stem cell transplant may …

vindesine
cyclophosphamide
vincristine
etoposide
stem cell transplantation
  • 30 views
  • 07 Nov, 2020
  • 28 locations