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Found 147 clinical trials
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AEWS1031: A Phase III Randomized Trial of Adding Vincristine-Topotecan-Cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-Metastatic Ewing Sarcoma

AEWS1031: A Phase III Randomized Trial of Adding Vincristine-Topotecan-Cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-Metastatic Ewing Sarcoma

  • 376 views
  • 08 Nov, 2020
  • 1 location
featured
N0577 (CODEL) Phase III Intergroup Study of Radiotherapy with Concomitant and Adjuvant Temozolomide versus Radiotherapy with Adjuvant PCV Chemotherapy in Patients with 1p/19q co-deleted Anaplastic Glioma or Low Grade Glioma

(Procarbazine, CCNU, and Vincristine) or radiation with temozolomide during and after radiation, to see which is better.  

brain tumor
oligodendroglioma
vincristine
temozolomide
brain tumors
  • 10 views
  • 22 Dec, 2020
  • 1 location
High Risk Neuroblastoma Study 1.8 of SIOP-Europe (SIOPEN)

of induction should receive 2 TVD (Topotecan, Vincristine, Doxorubicin) cycles. After Rapid COJEC induction, localized patients will proceed to consolidation. Patients aged 12-18 months at

granulocyte colony stimulating factor
metastatic neuroblastoma
isotretinoin
carboplatin
dinutuximab
  • 288 views
  • 28 Oct, 2020
  • 126 locations
Combination Chemotherapy in Treating Young Patients With Nonmetastatic Rhabdomyosarcoma

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. It is not yet known which combination chemotherapy regimen is more …

vinorelbine
doxorubicin
conventional surgery
carboplatin
cancer chemotherapy
  • 103 views
  • 07 Nov, 2020
  • 9 locations
Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more …

dexamethasone
lymphoid leukemia
asparaginase
cytarabine
combination chemotherapy
  • 1 views
  • 07 Nov, 2020
  • 5 locations
Chemotherapy Before and After Surgery in Treating Children With Wilm's Tumor

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving combination chemotherapy before surgery may shrink the tumor so it can be removed during surgery. Giving more chemotherapy after surgery may kill any remaining tumor cells. It is not …

tumor cells
conventional surgery
cyclophosphamide
nephroblastoma
  • 9 views
  • 07 Nov, 2020
  • 1 location
Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation Radiation Therapy and/or Surgery in Treating Patients With Ewing's Sarcoma

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy and kill more tumor cells. It is …

doxorubicin
ewing's sarcoma
conventional surgery
cancer chemotherapy
combination chemotherapy
  • 410 views
  • 07 Nov, 2020
  • 4 locations
Study in Localized and Disseminated Ewing Sarcoma

Ewing Sarcoma Primary objectives: Standard Risk R1: in a randomised trial, to examine whether add-on treatment with zoledronic acid in addition to induction and maintenance chemotherapy improves event-free survival in patients with localised Ewing sarcoma and good histological response or with initial tumour volume <200 mL compared to no add-on …

melphalan
metastasis
zoledronic acid
sarcoma of bone
  • 27 views
  • 08 Nov, 2020
  • 1 location
Biomarker Driven Intensified ChemoImmunotherapy With Early CNS Prophylaxis

This study is testing whether stratification of the patients according to biological risk factors for different treatment groups will improve the outcome of patients with clinically high diffuse large B-cell lymphoma (DLBCL).

da-epoch
burkitt's lymphoma
transformed lymphoma
t-cell lymphoma
large cell lymphoma
  • 32 views
  • 08 Mar, 2020
  • 16 locations
Combination Chemotherapy With or Without Filgrastim Before Surgery High-Dose Chemotherapy and Radiation Therapy Followed by Isotretinoin With or Without Monoclonal Antibody in Treating Patients With Neuroblastoma

RATIONALE: Colony-stimulating factors such as filgrastim may increase the number of immune cells found in bone marrow or peripheral blood and may help a person's immune system recover from the side effects of chemotherapy. Combining chemotherapy with peripheral stem cell transplant may allow the doctor to give higher doses of …

isotretinoin
carboplatin
monoclonal antibodies
stem cell transplantation
melphalan
  • 46 views
  • 07 Nov, 2020
  • 15 locations