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Found 29 clinical trials
Vinblastine for Leukoreduction in Newly Diagnosed AML and Hyperleukocytosis

Vinblastine can leukoreduce patients with newly diagnosed AML and hyperleukocytosis but clinical trials are lacking.

induction chemotherapy
hydroxyurea
  • 0 views
  • 24 Oct, 2021
Randomization of Cytarabine Monotherapy Versus Standard-of-Care Vinblastine/Prednisone for Frontline Treatment of Langerhans Cell Histiocytosis (TXCH LCH0115)

-care vinblastine/prednisone are used as front-line therapy while cytarabine therapy has been used as therapy for patients who develop recurrence. No alternate treatment strategy has been developed for

  • 12 views
  • 22 Sep, 2022
  • 9 locations
A Phase 3 Study of Selumetinib (NSC# 748727) or Selumetinib in Combination With Vinblastine for Non-NF1, Non-TSC Patients With Recurrent or Progressive Low-Grade Gliomas (LGGs) Lacking BRAFV600E or IDH1 Mutations

This phase III trial investigates the best dose of vinblastine in combination with selumetinib and the benefit of adding vinblastine to selumetinib compared to selumetinib alone in treating

  • 0 views
  • 15 Sep, 2022
  • 34 locations
A Study Comparing the Effects on Melanoma With High Dose IFN Alone vs Cisplatin Velban DTIC IL2 IFN and G CSF

What is the overall survival and disease-free survival between patients with high risk melanoma who recieve high dose interferon Alphe 2b versus Cisplatin, Vinblastine, DTIC plus IL-2 and

vinblastine
filgrastim
dacarbazine
interferon
  • 12 views
  • 07 Nov, 2020
  • 1 location
A Phase II Study to Determine Pembrolizumab as Frontline Treatment of Patients With Hodgkin Lymphoma

this disease and are unsuitable for standard treatment (adriamycin, bleomycin, vinblastine, dacarbazine ABVD).

chemotherapy regimen
vinblastine
bleomycin
adriamycin
dacarbazine
  • 4 views
  • 14 Dec, 2021
  • 6 locations
A Phase II/III Trial of MEDI4736 (Durvalumab) and Chemotherapy for Patients With High Grade Upper Tract Urothelial Cancer Prior to Nephroureterectomy

, vinblastine, doxorubicin, cisplatin, and gemcitabine work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading

  • 0 views
  • 21 Sep, 2022
  • 74 locations
Nivolumab in Combination With Metronomic Chemotherapy in Paediatrics Refractory / Relapsing Solid Tumors

controlled balanced 1:1 open-label trial comparing the efficacy of the metronomic chemotherapy regimen selected at the end of the previous stage (arm C: cyclophosphamide, capecitabine, vinblastine), with or

  • 0 views
  • 14 Jun, 2022
  • 7 locations
Pediatric Classical Hodgkin Lymphoma Consortium Study: cHOD17

-risk and intermediate- risk patients will be treated with bendamustine, etoposide, Adriamycin® (doxorubicin), bleomycin, Oncovin® (vincristine), vinblastine, and prednisone (BEABOVP) chemotherapy. High

chemotherapy regimen
pulse oximetry
renal function
bleomycin
etoposide
  • 12 views
  • 10 Aug, 2022
  • 6 locations
Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy (PLGG - MEKTRIC)

years independently from the chemotherapeutic scheme. The two current standard therapies are carboplatin plus vincristine during 81 weeks or a weekly IV administration of vinblastine during 70 weeks

  • 0 views
  • 28 Jul, 2022
  • 1 location
Phase II Study of Vinorelbine for Children With Recurrent Anaplastic Large Cell Lymphoma

The purpose of this study is to assess the efficiency and safety of vinorelbine in the treatment of relapsed / advanced ALCL in children and adolescents.

cancer
stem cell transplantation
  • 6 views
  • 18 Sep, 2022
  • 1 location