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Found 12 clinical trials
Arrhythmic Risk Stratification in Nonischemic Dilated Cardiomyopathy

Nonischemic dilated cardiomyopathy is a heterogeneous disease often associated with increased rates of sudden cardiac death. Although many algorithms have been proposed, risk stratification remains suboptimal, and implantable cardioverter-defibrillators are currently recommended only in patients with poor left ventricular function. However, most cases of sudden cardiac death occur at earlier …

  • 09 May, 2021
  • 1 location
Radiosurgery for the Treatment of Refractory Ventricular Extrasystoles and Tachycardias

Patients with refractory ventricular extrasystoles or tachycardia not eligible for catheter ablation will receive single fraction stereotactic body radiation therapy (cardiac radiosurgery) with

implantable cardioverter-defibrillators
catheter ablation
premature ventricular contractions
heart disease
  • 27 Jan, 2021
  • 3 locations
TAES for FPVCs: a Pragmatic Randomized Controlled Trial

This prospective, pragmatic, randomized controlled trial aims to evaluate the efficacy and safety of transcutaneous acupoint electrical stimulation (TAES) for patients with frequent premature ventricular contractions (FPVCs). Ninety participants will be randomized to TAES group and sham-TAES group with the ratio of 1:1. They will receive TAES plus usual care …

  • 26 Jan, 2021
  • 1 location
Elimination of VPB With Ablation Versus Anti-arrhythmic Drug Treatment

The ECTOPIA trial is a randomized, multicenter, clinical trial to assess elimination of ventricular premature beats (VPB) with catheter ablation versus optimal anti-arrhythmic drugs (AAD) treatment with flecainide/verapamil or sotalol.

  • 23 Jan, 2021
  • 1 location
LLTS to Treat Premature Ventricular Contractions

This randomized control trial is designed to explore the effect of low-level tragus stimulation in patients with frequent premature ventricular contractions.

  • 30 Jun, 2021
  • 1 location
Use of Adenosine to Determine the Electrophysiological Mechanism of Premature Ventricular Contractions

Unblinded, controlled, non-randomized, mechanistic study to determine whether physiological mechanisms underlying PVC are sensitive to adenosine. One hundred subjects undergoing clinically-indicated, standard-of-care cardiac electrophysiology study (EPS) procedure for PVCs will receive adenosine and/or verapamil to learn if their arrhythmias are inducible similarly to sustained ventricular tachycardia.

  • 04 Jun, 2021
  • 1 location
Angiotensin Receptor-Neprilysin Inhibition in Chagas Cardiomyopathy With Reduced Ejection Fraction: ANSWER-HF.

Chagas disease is considered by the World Health Organization (WHO) as one of the most neglected tropical diseases in the world, having relevance in many Latin America countries. In addition, it already affects North America, Europe, Asia and Oceania. Some studies suggest that chagasic heart failure has a worse prognosis, …

  • 15 May, 2021
  • 1 location
Mobile Cardiac Telemetry and Advanced Multi-Parameter Monitoring in Patients

To determine the associations among biometric data, arrhythmias, subject-reported symptoms and subject wellness.

  • 12 Jun, 2021
  • 20 locations
SHERLOCK 3CG Diamond Tip Confirmation System

This study is a single-arm, prospective, multi-center study to assess clinical performance of the SHERLOCK 3CG Diamond Tip Confirmation System (TCS) with MODUS II software for confirming correct tip position of peripherally inserted central catheters (PICCs) in adult subjects with altered cardiac rhythm.

ventricular extrasystoles
atrial fibrillation
12 lead ECG
  • 29 Jan, 2021
  • 11 locations
Personalized Treatment for Patients With Premature Ventricular Beats

Frequent premature ventricular beats (PVBs) are common, negatively affects the quality of life for many patients, and can lead to impaired contractile function. Rule-out of structural heart disease is key in the assessment of PVBs. Cardiac MR has a high sensitivity for structural heart disease, but the diagnostic gain from …

  • 26 Jan, 2021
  • 1 location