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Found 104 clinical trials
A Randomised Trial of S-ICD Implantation With and Without Defibrillation Testing

This study will test the hypothesis that implantation of a subcutaneous implantable cardioverter defibrillator (S-ICD) without performing a defibrillation test is non-inferior to S-ICD implant with a defibrillation test with regards to the primary endpoint failed first shock in a spontaneous arrhythmia episode when implant position is confirmed with PRAETORIAN …

  • 25 Jan, 2021
  • 41 locations
Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias Following Acute Myocardial Infarction (PROTECT-ICD)

information on myocardial viability, scar size and tissue heterogeneity. It has an emerging role as a predictor of mortality and spontaneous ventricular arrhythmia in patients with a previous MI. A

  • 23 Jan, 2021
  • 36 locations
Incidence of Ventricular Arrhythmias in Patients With Chronic Total Occlusion Recanalization

is related to ventricular arrhythmias (VA) is unknown. The purpose of this pilot study is to evaluate the incidence of VA after successful CTO recanalization, failed CTO recanalization and untreated

  • 11 Feb, 2021
  • 1 location
Epicardial Ablation in Brugada Syndrome to Prevent Sudden Death

A total of 150 patients will be randomized to perform catheter ablation or not in a 2:1 fashion in selected patients with Brugada-related symptoms (Ablation+ICD arm 105 patients vs ICD only 45 patients).

  • 24 Jan, 2021
  • 1 location
Myocardial Characterization of Arrhythmogenic Mitral Valve Prolapse (STAMP: STretch and Myocardial Characterization in Arrhythmogenic Mitral Valve Prolapse)

hemodynamic consequences of the mitral regurgitation. More recently, detection of myocardial fibrosis among patients with MVP and severe ventricular arrhythmia has been identified. Fibrosis could

  • 26 Jan, 2021
  • 1 location
Anakinra Versus Placebo for the Treatment of Acute MyocarditIS

. ANAKINRA, an IL-1 Blocker, is a new treatment that has never been evaluated in myocarditis. The benefit for the patient could be important with a reduction of heart failure and ventricular arrhythmias.

  • 27 Jan, 2021
  • 3 locations
Exercise Training in Patients With Cardioverter-Defibrillators

benefit from a cardiovascular training in terms of improved quality of life and reduction of ventricular arrhythmia. The data on feasibility, risk and therapeutic effects of exercise training

ventricular arrhythmia
left ventricular dysfunction
implantable cardioverter-defibrillators
heart failure
  • 07 Nov, 2020
  • 1 location
Influence of Sacubitril/Valsartan on Autonomic Cardiac Nervous System in Heart Failure Patients: an Exploratory Study

to have antiarrhythmic properties as it has been shown to significantly reduce ventricular arrhythmias in patients with implantable cardioverter defibrillators. Patients suffering from heart

  • 26 Jan, 2021
  • 1 location
Interleukin-1 Blockade for Treatment of Cardiac Sarcoidosis

, lymph nodes and the heart. In this latter case, cardiac sarcoidosis (CS) can lead to atrioventricular (AV) blocks, ventricular arrhythmias, heart failure (HF) and sudden cardiac death. Similar to other

  • 26 Jan, 2021
  • 2 locations
The Nordic Baltic Chronic Total Occlusion (CTO) Arrhythmia Study

In patients with a chronic total coronary occlusion (CTO ), clinically significant arrhythmia seems to be an important and a poorly investigated problem. The arrhythmia prevalence in an all-comer CTO-population is unknown, but in ICD-populations with ischemic heart disease, a CTO may be found in half of patients with life-threatening …

  • 18 Mar, 2021
  • 1 location