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Found 76 clinical trials
Extra-Corporeal Carbon Dioxide Removal in Exacerbations of Chronic Obstructive Pulmonary Disease

Cannula Oxygen Therapy (HFNCOT), potentially reducing the risk of ventilator induced lung injury, improving patient's comfort and probably allowing the adoption of a more physiologically "noisy" pattern

  • 0 views
  • 23 Jan, 2021
  • 1 location
Assessment of Regional Lung Ventilation Distribution During Supraglottic and Subglottic Jet Ventilation by EIT.

Objective: To estimate regional lung volume changes by electrical impedance tomography (EIT) during supra- and subglottic jet ventilation via the jet laryngoscope and LaserJet catheter for performing laryngotracheal surgery. Design: A monocentric, prospective, randomized study. Patients: Patients who require elective micro laryngo-tracheal surgery under jet ventilation. Interventions: Patients undergoing elective …

  • 0 views
  • 10 Sep, 2021
  • 1 location
Careful Ventilation in Acute Respiratory Distress Syndrome (COVID-19)

This is a multicenter randomized controlled clinical trial with an adaptive design assessing the efficacy of setting the ventilator based on measurements of respiratory mechanics (recruitability and effort) to reduce Day 60 mortality in patients with acute respiratory distress syndrome (ARDS). The CAVIARDS study is also a basket trial; a …

positive end expiratory pressure
mechanical ventilation
covid-19
acute respiratory distress
pao2
  • 17 views
  • 23 Jul, 2021
  • 23 locations
Pressure Support Ventilation During Laparoscopic and Abdominal Robotic Surgery.

This study is a single-center, blind, prospective, randomized, controlled trial of pressure support ventilation (PSVpro) versus pressure control ventilation - volume guaranteed (PCV - VG) during laparoscopic and robotic abdominal surgery.

  • 0 views
  • 02 Apr, 2021
  • 1 location
Assessing Ventilator Safety in Patients on Pressure-Support Ventilation

ASOP is a prospective cohort study comparing three methods for assessing risk of self-induced lung injury in patients with acute respiratory failure being managed with pressure-support ventilation. We will describe the relationship between three different assessment methods for risk of self-induced lung injury and compare them to a gold standard …

mechanical ventilation
  • 0 views
  • 27 Dec, 2021
  • 1 location
Enhanced Lung Protective Ventilation With ECCO2R During ARDS

Acute Respiratory Distress Syndrome (ARDS) is associated with a mortality rate of 30 - 45 % and required invasive mechanical ventilation (MV) in almost 85 % of patients[1]. During controlled MV, driving pressure (i.e., the difference between end-inspiratory and end-expiratory airway pressure) depends of both tidal volume and respiratory system …

renal replacement therapy
aeration
acute respiratory distress syndrome
acute respiratory distress
FIO2
  • 17 views
  • 25 Feb, 2021
  • 1 location
Clinical Decision Support Tool in PARDS Pilot Study

Previous clinical trials in adults with acute respiratory distress syndrome (ARDS) have demonstrated that ventilator management choices can improve Intensive Care Unit (ICU) mortality and shorten time on mechanical ventilation. This study seeks to scale an established Clinical Decision Support (CDS) tool to facilitate dissemination and implementation of evidence-based research …

acute respiratory distress
mechanical ventilation
assisted breathing
  • 0 views
  • 16 Aug, 2021
  • 8 locations
Effects of Large Tidal Volumes Despite Minimal Inspiratory Support in Spontaneously Ventilated Intubated Resuscitation Patients. Pathophysiological Exploratory Study.

Some ICU ventilated patients might present with large tidal volume despite very low or inexistant presser support. Patient-Self Inflicted Lung Injury (P-SILI) might appear related with large alveolar stretch an distension. Two clinical presentations are observed: patients with or without respiratory distress signs such as supra-clavicular depression and thoracic-abdominal asynchronies. …

positive end expiratory pressure
mechanical ventilation
  • 0 views
  • 06 Oct, 2021
  • 1 location
Mid and Standard Frequency Ventilation in Infants With Respiratory Distress Syndrome

ventilator-free days after randomization and reduce the risk of ventilator induced lung injury.

lung injury
pulmonary surfactant
ventilator-induced lung injury
respiratory distress
  • 43 views
  • 02 Nov, 2021
  • 2 locations
Impact of Decreasing Respiratory Rate on Lung Injury Biomarkers in ARDS Patients

rate, close to 40%. Mechanical ventilation is a fundamental therapy to improve gas exchange, however, it can also induce further lung injury, a phenomenon known as ventilator induced lung injury (VILI

  • 0 views
  • 26 Jan, 2021
  • 1 location