Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 46 clinical trials
None
Endotracheal Tubes to Prevent Ventilator-Associated Pneumonia

Researchers are looking at two different types of breathing tubes to see if one is better than the other at preventing pneumonia. One of the tubes has a design features to prevent leakage of fluids from the mouth and the back of the throat into the lower airways and lungs. …

intubation
  • 0 views
  • 29 May, 2021
  • 2 locations
None
Study Comparing Inhaled Amikacin Versus Placebo to Prevent Ventilator Associated Pneumonia

The objective of the study is to prove that after the third day of invasive mechanical ventilation a three-day course of inhaled amikacin reduces the incidence of subsequent VAP. Parallel two group double blind randomized controlled clinical trial. Individual randomization, performed on day 4 of invasive mechanical ventilation, will be …

antibiotics
mechanical ventilation
antibiotic therapy
  • 3 views
  • 01 Mar, 2021
  • 42 locations
None
Efficacy, Safety, and Tolerability of ATM-AVI in the Treatment of Serious Infection Due to MBL-producing Gram-negative Bacteria

intra-abdominal infections (cIAI), nosocomial pneumonia (NP) including hospital acquired pneumonia (HAP) and ventilator associated pneumonia (VAP), complicated urinary tract infections (cUTI), or

  • 3 views
  • 13 Dec, 2021
  • 11 locations
None
Evaluation of Early CRRT InTerventions in Patients With ECMO(ELITE)

Extracorporeal membrane oxygenation (ECMO) is of great value in supporting patients with cardiac shock. More than 80% ECMO patients will develop renal catastrophe that continuous renal replacement therapy (CRRT) is required. The evidence is conflict as to whether early CRRT improves outcomes. Early CRRT before a definite indication developed may …

  • 0 views
  • 23 Jan, 2021
  • 1 location
None
Pharmacokinetics of Nebulized Amikacin in Patients With Pneumonia Undergoing Mechanical Ventilation

Inclusion of patients undergoing mechanical ventilation and presenting a pneumonia in order to determine serum pharmacokinetics of nebulized amikacin. The primary aim is to determine the dose of amikacin to be nebulized in order to observe amikacin serum concentrations close to but inferior to those observed after standart intravenous amikacin …

mechanical ventilation
  • 1 views
  • 07 Nov, 2020
  • 2 locations
None
Nurses-driven Capnography-guided Protocol Weaning From the Mechanical Ventilation at Bedside: A Feasibility Study

safety evaluation with report of hospital mortality, ventilator associated-pneumonia, autoextubation, length of stay and the number of ABG/patient/day during the study period. Inclusion critera: all

  • 0 views
  • 21 Aug, 2021
  • 1 location
None
Comparison of Time-restricted Feeding and Continuous Feeding in Critically Ill Patients

In the nutrition guideline (A.S.P.E.N guideline), there was no recommendation about the feeding type in enteral feeding of critically ill patients. Continuous feeding is the most popular feeding type in ICU because of its less nursing burden and reducing the aspiration incidence theoretically. However, some previous studies demonstrated that there …

  • 1 views
  • 25 Jan, 2021
  • 1 location
None
A Single Site Safety and Tolerability Study of HBOC-201 in Trauma Subjects

The main purpose of this study is to determine if HBOC-201 is safe and tolerable to trauma subjects, when given to treat the inadequate supply of blood and nutrients to tissues and organs.

traumatic brain injury
systolic blood pressure
  • 208 views
  • 07 Nov, 2020
  • 1 location
None
A Study to Determine the Efficacy, Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI) ± Metronidazole (MTZ) Versus Meropenem (MER) ± Colistin (COL) for the Treatment of Serious Infections Due to Gram Negative Bacteria.

A Phase 3 comparative study to determine the efficacy, safety and tolerability of Aztreonam-Avibactam (ATM-AVI) ± Metronidazole (MTZ) versus Meropenem (MER) ± Colistin (COL) for the treatment of serious infections due to Gram negative bacteria.

metronidazole
chest x-ray
ATM
antibiotic therapy
colistin
  • 959 views
  • 19 Jan, 2022
  • 175 locations
None
Safety Tolerability and Pharmacokinetics of Cefiderocol in Hospitalized Pediatric Patients

complicated urinary tract infection (cUTI), hospital-acquired pneumonia (HAP), or ventilator-associated pneumonia (VAP).

antibiotics
pneumonia
renal function
  • 43 views
  • 07 Aug, 2021
  • 21 locations