Found 146 clinical trials
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Pediatrics/Neonatology
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Currently Recruiting
Prophylaxis of Thromboembolic Complications Trial: Thromboprophylaxis Needed in Below Knee Plaster Cast Immobilization for Ankle and Foot Fractures
Objective: The purpose of this study is to determine the need for thromboprophylaxis in patients with a fracture of the lower extremity being treated conservatively in a below-knee plaster cast and to assess if both of the two tested prophylactic treatments are effective for this indication. Hypothesis: Nadroparine and Fondaparinux …
- 30 views
- 07 Nov, 2020
- 2 locations
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Multi-country trial
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Heparin Anticoagulation in Septic Shock
This study is a pragmatic open-label international randomized trial comparing therapeutic dose intravenous unfractionated heparin (UFH) to standard care venous thromboprophylaxis in patients diagnosed with septic shock.
- 121 views
- 04 Feb, 2021
- 50 locations
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Phase 2 trial
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Accepting pediatric ages
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Accepting Seniors
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10s of participants
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An interventional trial
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For all genders
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Cardiology/Vascular Diseases
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Currently Recruiting
Oral Anticoagulant Apixaban for Treatment of Venous Thromboembolism
Patients who have developed a venous thrombosis will receive apixaban to treat and prevent a secondary thromboembolism.
- 2 views
- 26 Jan, 2021
- 1 location
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Cardiology/Vascular Diseases
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Currently Recruiting
Impact of Early Debriefing and Enhanced Educative Components on Direct Oral Anticoagulant Adherence After Venous Thromboembolism.
Venous thromboembolism (VTE) is a frequent multifactorial and potential life-threatening disease. Once VTE has been diagnosed, anticoagulation should be started and prolonged for at least three
- 1 views
- 26 Jan, 2021
- 15 locations
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Cardiology/Vascular Diseases
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Currently Recruiting
Role of Statin in Venous Dysfunction in Patients With Venous Thromboembolism Event
Participants between the ages of 19 and 70 who were initially diagnosed with venous thromboembolism and were accompanied by dyslipidemia (LDL> = 100 mg / dl) were enrolled.
- 13 views
- 23 Jan, 2021
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Hematology
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Currently Recruiting
A Study of Dabigatran Etexilate as Primary Treatment of Malignancy Associated Venous Thromboembolism
This trial aims at determining if dabigatran is effective in the treatment of malignancy associated VTE. Tolerance and safety of dabigatran will also be assessed. This is a single armed trial of dabigatran in patients with malignancy associated VTE. The target recruitment is 99 consecutive patients with active malignancy and …
- 31 views
- 22 Jan, 2021
- 1 location
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Cardiology/Vascular Diseases
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Currently Recruiting
Rivaroxaban and Vitamin K Antagonists for the Anticoagulation for the Implantation of Vena Cava Filters
The purpose of this study is to evaluate the efficacy and safety of new oral anticoagulants and vitamin K antagonists for the anticoagulation for the implantation of vena cava filters in patients with deep venous thrombosis.
- 0 views
- 25 Jan, 2021
- 7 locations
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Cardiology/Vascular Diseases
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Currently Recruiting
Medically Ill Hospitalized Patients for COVID-19 THrombosis Extended ProphyLaxis With Rivaroxaban ThErapy: The MICHELLE Trial
The Michelle trial is expected to provide high-quality evidence around the role of extended thromboprophylaxis in COVID-19 and will help guide medical decisions in clinical practice.
- 0 views
- 27 Jan, 2021
- 1 location
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Multi-country trial
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Phase 3 trial
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Accepting pediatric ages
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Cardiology/Vascular Diseases
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Currently Recruiting
Pilot Feasibility and Safety of Administering Weight Adjusted Fixed LMWH Dose
Background Enoxaparin is a commonly used low molecular weight heparin (LMWH) for the treatment of neonatal and children thrombosis that is monitored with anti-factor Xa (anti-Xa) levels. However, this therapeutic range of anti-Xa (0.5 - 1.0 u/ml) was extrapolated from adult studies. The burden of pain to neonates due to …
- 9 views
- 24 Jan, 2021
- 4 locations
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Phase 1 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For females only
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Cardiology/Vascular Diseases
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Currently Recruiting
Apixaban vs Enoxaparin Following Microsurgical Breast Reconstruction-An RCT
Subcutaneous enoxaparin is currently the gold standard for VTE chemoprophylaxis. However, the efficacy of chemoprophylaxis with subcutaneous enoxaparin is affected by patient-level factors, thus, resulting in VTE events despite guideline-compliant prophylaxis. A population at particular risk is the growing number of patients who undergo autologous breast reconstruction. Direct oral anticoagulants …
- 0 views
- 26 Jan, 2021
- 1 location