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Found 146 clinical trials
Prophylaxis of Thromboembolic Complications Trial: Thromboprophylaxis Needed in Below Knee Plaster Cast Immobilization for Ankle and Foot Fractures

Objective: The purpose of this study is to determine the need for thromboprophylaxis in patients with a fracture of the lower extremity being treated conservatively in a below-knee plaster cast and to assess if both of the two tested prophylactic treatments are effective for this indication. Hypothesis: Nadroparine and Fondaparinux …

immobilisation
nadroparin
thromboembolism
fondaparinux
  • 30 views
  • 07 Nov, 2020
  • 2 locations
Heparin Anticoagulation in Septic Shock

This study is a pragmatic open-label international randomized trial comparing therapeutic dose intravenous unfractionated heparin (UFH) to standard care venous thromboprophylaxis in patients diagnosed with septic shock.

lactic acid
vasoconstrictor
norepinephrine
systolic blood pressure
vasopressin
  • 121 views
  • 04 Feb, 2021
  • 50 locations
Oral Anticoagulant Apixaban for Treatment of Venous Thromboembolism

Patients who have developed a venous thrombosis will receive apixaban to treat and prevent a secondary thromboembolism.

direct bilirubin
thrombosis
venous thromboembolism
renal function
clot
  • 2 views
  • 26 Jan, 2021
  • 1 location
Impact of Early Debriefing and Enhanced Educative Components on Direct Oral Anticoagulant Adherence After Venous Thromboembolism.

Venous thromboembolism (VTE) is a frequent multifactorial and potential life-threatening disease. Once VTE has been diagnosed, anticoagulation should be started and prolonged for at least three

apixaban
anticoagulation therapy
anticoagulants
  • 1 views
  • 26 Jan, 2021
  • 15 locations
Role of Statin in Venous Dysfunction in Patients With Venous Thromboembolism Event

Participants between the ages of 19 and 70 who were initially diagnosed with venous thromboembolism and were accompanied by dyslipidemia (LDL> = 100 mg / dl) were enrolled.

cholesterol level
rosuvastatin 20 mg
pulmonary embolism
fasting
blood test
  • 13 views
  • 23 Jan, 2021
A Study of Dabigatran Etexilate as Primary Treatment of Malignancy Associated Venous Thromboembolism

This trial aims at determining if dabigatran is effective in the treatment of malignancy associated VTE. Tolerance and safety of dabigatran will also be assessed. This is a single armed trial of dabigatran in patients with malignancy associated VTE. The target recruitment is 99 consecutive patients with active malignancy and …

tinzaparin
thrombosis
venous thromboembolism
doppler ultrasound
dabigatran
  • 31 views
  • 22 Jan, 2021
  • 1 location
Rivaroxaban and Vitamin K Antagonists for the Anticoagulation for the Implantation of Vena Cava Filters

The purpose of this study is to evaluate the efficacy and safety of new oral anticoagulants and vitamin K antagonists for the anticoagulation for the implantation of vena cava filters in patients with deep venous thrombosis.

rivaroxaban
vena cava filter
vitamin k antagonist
anticoagulation therapy
nadroparin
  • 0 views
  • 25 Jan, 2021
  • 7 locations
Medically Ill Hospitalized Patients for COVID-19 THrombosis Extended ProphyLaxis With Rivaroxaban ThErapy: The MICHELLE Trial

The Michelle trial is expected to provide high-quality evidence around the role of extended thromboprophylaxis in COVID-19 and will help guide medical decisions in clinical practice.

  • 0 views
  • 27 Jan, 2021
  • 1 location
Pilot Feasibility and Safety of Administering Weight Adjusted Fixed LMWH Dose

Background Enoxaparin is a commonly used low molecular weight heparin (LMWH) for the treatment of neonatal and children thrombosis that is monitored with anti-factor Xa (anti-Xa) levels. However, this therapeutic range of anti-Xa (0.5 - 1.0 u/ml) was extrapolated from adult studies. The burden of pain to neonates due to …

pulmonary embolism
ct scan
enoxaparin
thrombosis
deep vein thrombosis
  • 9 views
  • 24 Jan, 2021
  • 4 locations
Apixaban vs Enoxaparin Following Microsurgical Breast Reconstruction-An RCT

Subcutaneous enoxaparin is currently the gold standard for VTE chemoprophylaxis. However, the efficacy of chemoprophylaxis with subcutaneous enoxaparin is affected by patient-level factors, thus, resulting in VTE events despite guideline-compliant prophylaxis. A population at particular risk is the growing number of patients who undergo autologous breast reconstruction. Direct oral anticoagulants …

apixaban 2.5 mg
anesthesia
enoxaparin 40mg/0.4ml prefilled syringe
apixaban
enoxaparin
  • 0 views
  • 26 Jan, 2021
  • 1 location